Protein Alignment Adgf-E and YBR284W

DIOPT Version :10

• Sequence 1: NP_610977.1
• Gene: Adgf-E / 36627
• FlyBaseID: FBgn0033952
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_009843.3
• Gene: YBR284W / 852587
• SGDID: S000000488
• Length: 797
• Species: Saccharomyces cerevisiae
• Alignment Length: 496
• Identity: 100/496 - (20%)
• Similarity: 170/496 - (34%)
• Gaps: 145/496 - (29%)

  Fly    28 HNPEKMTLLEMLGTTNLRKSTPKDYRILREI-FNSFERYSGVGNDIQLTLPERAANELIMCEKKR 91
            |:.|:|        ...:|...||:...|:| .|..  .||..:..|||       |.|..:.::
Yeast   257 HSKEEM--------RQSKKVPHKDFYNCRKIDLNLL--LSGCFSQWQLT-------EFIWTKLRK 304

  Fly    92 EYEKGIMDPSKFAPGHHIFQVLTKVKKSPLFQILRRMPKGAALKAHDTSMCSSRVVIEIT----Y 152
            |.::.|  ...|...|.....|.||......|...      .||..|.|......||.:.    .
Yeast   305 EPDRVI--HQAFNGSHITLSQLFKVNFEETGQFFN------GLKIIDDSFLEWYKVIYLAKYHLV 361

  Fly   153 RDNLWVCTTQNGCRVEEFRFAKDKPKDVSFENGEWQPMEKLRELRGEENLRKYL--QMRFSMYPL 215
            .|.:.:.|..:|.::..:..||...:..::.|||:     |.||     |:.:|  ....|.|.|
Yeast   362 NDEMEIHTGSHGKQLRYYLIAKTFLEFDNYINGEY-----LAEL-----LKTFLIKPQEESKYQL 416

  Fly   216 ASFTTNAHAWRHMMGIFGLLDGLLQYAPVWGDYYYNALKEFYADGVQY-LEVRSVLPQLYSLDGS 279
            ...:.:...:.|...  ..:|........|.::|     ..:::.::: :.:..:.|:||
Yeast   417 CQLSVDFQFYLHYDN--SDVDNWWMVFANWLNHY-----NIFSNNIRWNIRISRIYPELY----- 469

  Fly   280 RMPKRETVQIYKDTLERFKKEHPGFIDS-----KLIYAPIRHVQPELVGEYI-KECTELNKEFPS 338
                                 |.|.:.:     .||:.|:.:.:     .|: |....:..:|.|
Yeast   470 ---------------------HTGKVKNFQEYLNLIFKPLFNAE-----NYLHKSLGPILLKFLS 508

  Fly   339 FVVGFDLVGQEDVGHPLSNFAAELLKLP------------DHIHFYFHAGQTNWYGSHVDQNLLD 391
            .|...||..|:...:...||.| :..||            ....:|.:...|..  :|:.|.|
Yeast   509 QVSSIDLCIQDTDNYIWKNFTA-VSCLPKDWTSGGDNPTISQYMYYVYVNLTKL--NHIRQAL-- 568

  Fly   392 AIVLGTKRIGHGYTITKHPVLMRLAKYLNIALEVCPVS-NQVLQLGS--DYRSHPAATLIAENVP 453
                      |..|.|             :.....|.| |:..|..:  ::..|..|  |..|
Yeast   569 ----------HQNTFT-------------LRSSCSPTSMNRTSQFSNTLNFTEHTEA--ILNN-- 606

  Fly   454 MVIASGSPGF------WRAAP-LSHDFYMAFLG--IAPMNA 485
            .::|.|  ||      |.|.| |.:.||::.:.  :||:|:
Yeast   607 FLLACG--GFLNAENLWNAPPSLVYLFYLSQIPMVVAPLNS 645

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adgf-E	NP_610977.1	adm_rel	52..527	CDD:273620	94/472 (20%)
YBR284W	NP_009843.3	metallo-dependent_hydrolases	219..791	CDD:469705	100/496 (20%)