DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adgf-E and Adal

DIOPT Version :9

Sequence 1:	NP_610977.1	Gene:	Adgf-E / 36627	FlyBaseID:	FBgn0033952	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	XP_011238139.1	Gene:	Adal / 75894	MGIID:	1923144	Length:	396	Species:	Mus musculus

Alignment Length:	371	Identity:	87/371 - (23%)
Similarity:	140/371 - (37%)	Gaps:	99/371 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   199 EENLRKYLQMRFSMYP-LASFTTNAHAWRHMMGIFGLLDGLLQYAPVWGDYYYNALKEFYADGVQ 262
            ::..::.||..|.|:. :...||:|             :.:|....       :.:|||..|||:
Mouse    55 DKGKKRTLQECFQMFQVIHQLTTSA-------------EDILMVTK-------DVIKEFADDGVK 99

  Fly   263 YLEVRSVLPQLYSLDGSRMPKRETVQIYKDTLERFKKEHPGFIDSKLIYAPIRHVQPELVGEYIK 327
            |||:||. |:..:..|  |.::..|:...:.:::.|:|:.. ||.:.:.|..|...|.:.    :
Mouse   100 YLELRST-PREENATG--MTRKTYVESVLEGIKQCKQENLD-IDVRYLMAIDRRGGPTIA----R 156

  Fly   328 ECTELNKEF----PSFVVGFDLVGQEDVG------HPLSNFAAELLKLPDHIHFYFHAGQTNWYG 382
            |..||.|||    .:.|:|.||.|...:|      .||.......|||..|:....:..:.|
Mouse   157 ETVELAKEFFLSTENTVLGLDLSGDPTIGQANDFLEPLLEAKKAGLKLALHLAEIPNREKEN--- 218

  Fly   383 SHVDQNLLDAIVLGTKRIGHG--------------------------------YTITKHPVLMR- 414
                |.||..:   ..|||||                                |.....|:|:|
Mouse   219 ----QMLLSLL---PDRIGHGTFLSASEAGALDQVDFVRQHQIPLVLEANAELYMCRAGPLLLRH 276

  Fly   415 -------LAKYLNIALEVCPVSNQVLQLGSDYRSHPAATLIAENVPMVIASGSPGFWRAAPLSHD 472
                   .::.:||..|:|..||...|....|..|......:...|.||.:...|.: |..||.:
Mouse   277 IPTQNKSTSQVMNILWELCLTSNIKSQTVPSYDQHHFGFWYSIAHPSVICTDDKGVF-ATYLSQE 340

  Fly   473 FYMA--FLGIAPMNA-DLKFLKRTAKNSIKYSSLKDEAKAEAMEKW 515
            :.:|  ...:.|... ||.:      .||.|....|..::|..::|
Mouse   341 YQLAAETFNLTPFQVWDLSY------ESINYIFACDNTRSELRKRW 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adgf-E	NP_610977.1	A_deaminase_N	46..125	CDD:285627
		adm_rel	52..527	CDD:273620	87/371 (23%)
		ADGF	105..519	CDD:238646	87/371 (23%)
Adal	XP_011238139.1	ADA_AMPD	17..380	CDD:238250	86/369 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1816
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R23
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840