DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Adgf-E and adah-1

DIOPT Version :9

Sequence 1:	NP_610977.1	Gene:	Adgf-E / 36627	FlyBaseID:	FBgn0033952	Length:	539	Species:	Drosophila melanogaster
Sequence 2:	NP_501087.1	Gene:	adah-1 / 177469	WormBaseID:	WBGene00015551	Length:	391	Species:	Caenorhabditis elegans

Alignment Length:	285	Identity:	65/285 - (22%)
Similarity:	115/285 - (40%)	Gaps:	47/285 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   250 YNALKEFYADGVQYLEVRSVLPQLYSLDGSRMPKRETVQIYKDTLERFKKEHPGFIDSKLIYAPI 314
            |...::.:.:||.|.|.|.....|...|...:.....|...|...:|.:|:..  |.::.|...|
Worm   125 YELCEDQHNNGVVYFEGRYSPHLLLCNDYPEVTAAHVVAAVKKGFDRGEKQFG--IKARSILCCI 187

  Fly   315 RHVQ---PELVGEYIKECTELNKEFPSFVVGFDLVGQEDVGHPLSNFAAELLKLPD--------H 368
            |.:.   |:|:.:...:..:|.      ||..|:.|        |...|:....|:        |
Worm   188 RGLDKKFPQLILDLATDLKQLG------VVAIDVAG--------SAHGADEQYEPEVVAAFQEAH 238

  Fly   369 ---IHFYFHAGQTNWYGSHVDQNLLDAIV-LGTKRIGHGYTITK--HPVLMRLAKYLNIALEVCP 427
               ||...|||:     |...:.::.||. :..:||||||.:.:  ...|.......|:.||.||
Worm   239 KRGIHRTVHAGE-----SGGPKEVIKAIEDMYAERIGHGYRVMRDEEMYLEHFVNSKNVHLEACP 298

  Fly   428 VSNQVLQLGS---DYRSHPAATLIAENVPMVIASGSPGFWRAAPLSHDFYMAFLGIAPMNADLKF 489
            .|:  :..|:   |:::||.|....::|...::...|..:..:.||.    ..|....:..|:..
Worm   299 YSS--VMTGAVPLDWKNHPIARWAKDDVNFSVSRDDPTCFDNSMLSE----LTLVHKQIGLDVHQ 357

  Fly   490 LKRTAKNSIKYSSLKDEAKAEAMEK 514
            |.:...|:.:...|.::.|||.:::
Worm   358 LWKAQLNAARSCFLPEDEKAELVKR 382

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Adgf-E	NP_610977.1	A_deaminase_N	46..125	CDD:285627
		adm_rel	52..527	CDD:273620	65/285 (23%)
		ADGF	105..519	CDD:238646	65/285 (23%)
adah-1	NP_501087.1	ADA	48..383	CDD:238645	65/285 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R23
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940