Protein Alignment Adgf-E and MAPDA

DIOPT Version :10

• Sequence 1: NP_610977.1
• Gene: Adgf-E / 36627
• FlyBaseID: FBgn0033952
• Length: 539
• Species: Drosophila melanogaster
• Sequence 2: NP_001311295.1
• Gene: MAPDA / 161823
• HGNCID: 31853
• Length: 355
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 77/284 - (27%)
• Similarity: 113/284 - (39%)
• Gaps: 46/284 - (16%)

  Fly   251 NALKEFYADGVQYLEVRSVLPQLYSLDGSRMPKRETVQIYKDTLERFKKEHPGFIDSKLIYAPIR 315
            :.:|||..|||:|||:||. |:..:..|  |.|:..|:...:.:::.|:|:.. ||.:.:.|..|
Human    89 DVIKEFADDGVKYLELRST-PRRENATG--MTKKTYVESILEGIKQSKQENLD-IDVRYLIAVDR 149

  Fly   316 HVQPELVGEYIKECTELNKEFPSFVVGFDLVGQEDVG------HPLSNFAAELLKLPDHIHFYFH 374
            ...|.:..|.:|...|........|:|.||.|...||      .||.......|||..|:
Human   150 RGGPLVAKETVKLAEEFFLSTEGTVLGLDLSGDPTVGQAKDFLEPLLEAKKAGLKLALHL----- 209

  Fly   375 AGQTNWYGSHV------DQNLLDAIVLGTKRIGHGYTITKHP----VLMRLAKYLNIALEVCPVS 429
                    |.:      .|.|||.:   ..|||||..:....    .|:...:...|.||:|..|
Human   210 --------SEIPNQKKETQILLDLL---PDRIGHGTFLNSGEGGSLDLVDFVRQHRIPLELCLTS 263

  Fly   430 NQVLQLGSDYRSHPAATLIAENVPMVIASGSPGFWRAAPLSHDFYMA---FLGIAPMNADLKFLK 491
            |...|....|..|......:...|.||.:...|.: |..||.::.:|   |........||.:
Human   264 NVKSQTVPSYDQHHFGFWYSIAHPSVICTDDKGVF-ATHLSQEYQLAAETFNLTQSQVWDLSY-- 325

  Fly   492 RTAKNSIKYSSLKDEAKAEAMEKW 515
                .||.|....|..::|..:||
Human   326 ----ESINYIFASDSTRSELRKKW 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adgf-E	NP_610977.1	adm_rel	52..527	CDD:273620	77/284 (27%)
MAPDA	NP_001311295.1	ADA_AMPD	18..345	CDD:238250	75/282 (27%)