Protein Alignment Had2 and HADH

DIOPT Version :9

• Sequence 1: NP_610974.1
• Gene: Had2 / 36624
• FlyBaseID: FBgn0033949
• Length: 315
• Species: Drosophila melanogaster
• Sequence 2: NP_001171634.3
• Gene: HADH / 3033
• HGNCID: 4799
• Length: 331
• Species: Homo sapiens
• Alignment Length: 273
• Identity: 68/273 - (24%)
• Similarity: 119/273 - (43%)
• Gaps: 24/273 - (8%)

  Fly     6 IGIVGSGLIGRAWAMLFAAAGYRVQLYDILESQLATALQELDKDLHRLEEQSALRGNIRASEQF- 69
            :.::|.||:|...|.:.||.|:.|.|.|..|..||.:.:.:::.|.::.::. ...|::|.::|
Human    30 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKK-FAENLKAGDEFV 93

  Fly    70 ----ALIGVTTRLEELTREAVHIQECVPEVLHLKKSLYSQLDELLEEQTVVASSTSTFMPSLYSE 130
                :.|..:|....:......:.|.:.|.|.:|..|:.:||:...|.|:.||:||:...:..:.
Human    94 EKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIAN 158

  Fly   131 GLQKRQQMLVAHPLNPPYFIPLVEIVPAPWTSPSAVERTRDLMLSLGQRPVTLKREIQGFATNRI 195
            ...::.:....|..||...:.|||::..|.||....|...|...:||:.||:.| :..||..||:
Human   159 ATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGKHPVSCK-DTPGFIVNRL 222

  Fly   196 QYAILNEVWRLV----------GSGI-------LSVADVDRVLSQGLGLRYALLGSLETAHLNAP 243
            ....|.|..||.          .||:       .|..|:|..:..|.|........|:...|:..
Human   223 LVPYLMEAIRLYERDFQTCGDSNSGLGFSLKGDASKEDIDTAMKLGAGYPMGPFELLDYVGLDTT 287

  Fly   244 GGVADYFQRFGGE 256
            ..:.|.:.....|
Human   288 KFIVDGWHEMDAE 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Had2	NP_610974.1	PRK06129	5..312	CDD:235706	68/273 (25%)
		3HCDH_N	5..184	CDD:280833	48/182 (26%)
		3HCDH	189..>256	CDD:279114	18/83 (22%)
HADH	NP_001171634.3	FadB	27..330	CDD:224170	68/273 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1250
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	1.028321	Normalized mean entropy	S3790
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.760