Protein Alignment Su(var)2-HP2 and CHS5

DIOPT Version :10

• Sequence 1: NP_610972.2
• Gene: Su(var)2-HP2 / 36621
• FlyBaseID: FBgn0026427
• Length: 3257
• Species: Drosophila melanogaster
• Sequence 2: NP_013434.1
• Gene: CHS5 / 851041
• SGDID: S000004322
• Length: 671
• Species: Saccharomyces cerevisiae
• Alignment Length: 696
• Identity: 148/696 - (21%)
• Similarity: 254/696 - (36%)
• Gaps: 182/696 - (26%)

  Fly   356 EQSAASDKEANKKERD-LEPPEASSSAKSSASK-ASGSRKLYDVANNATLEAVERMSLDLAE--- 415
            :...:.:.|..||:|: .:..:|....|....| .|...|:.:|...:.:.|.:.:.|..|:
Yeast    46 KMQVSQNLEEEKKQRNHFKSIQAKILEKYGTHKPESPVLKIVNVTQTSCVLAWDPLKLGSAKLKS 110

  Fly   416 ----------------------QIMEIDVERSYEFEKRSASKSRSLSRSKIPADSSTSQLGHVRK 458
                                  :|..:.|:..|||:.:..:.|.:|...|:..  .|.::..:..
Yeast   111 LILYRKGIRSMVIPNPFKVTTTKISGLSVDTPYEFQLKLITTSGTLWSEKVIL--RTHKMTDMSG 173

  Fly   459 LTYSSERLDQPEPLGTQLRRSKSESLPKRG-RPRGQKQRKNRGATMEEKSANCRDGEGEPVKRKR 522
            :|.....||   ||........|:.|...| ||      ..|...::.....|.|.:.|....:.
Yeast   174 ITVCLGPLD---PLKEISDLQISQCLSHIGARP------LQRHVAIDTTHFVCNDLDNEESNEEL 229

  Fly   523 GRPR----KIIPKEEAKTAETENTI-----------ESLNTNV---PLS---IDTSKEN------ 560
            .|.:    .|:..|..:..|.|..|           :|:..|.   |::   :..||||
Yeast   230 IRAKHNNIPIVRPEWVRACEVEKRIVGVRGFYLDADQSILKNYTFPPVNEEELSYSKENEPVAEV 294

  Fly   561 ------PETETVNLEVPIKQDELVSDLDNAK---ELTGSTNLPQDDIE-----MASNHQETDLKC 611
                  || :|.::|.....::..|:...||   |.:|....|...:|     ..:...||.::.
Yeast   295 ADENKMPE-DTTDVEQVASPNDNESNPSEAKEQGEKSGHETAPVSPVEDPLHASTALENETTIET 358

  Fly   612 APDRVALDKSE--STPKVEEEQLCKVDTPSDTALDE--SKVSESAKNHIELEDKDKDKEETQKES 672
            ....|...|||  .||.:||.   |.|:.::..::|  ..|:||:.|......|.:|.:.
Yeast   359 VNPSVRSLKSEPVGTPNIEEN---KADSSAEAVVEEPNEAVAESSPNEEATGQKSEDTDT----- 415

  Fly   673 PNGNSKETNENSVIVTNEVELPAKKAEAKAEAGNIVEESDSQLAEDFKLAEEILAAEVGKGVE-A 736
               :|.|..:|..:.|.||   |:.......||...|.:|....|..:...||...||.:.:| |
Yeast   416 ---HSNEQADNGFVQTEEV---AENNITTESAGENNEPADDAAMEFGRPEAEIETPEVNESIEDA 474

  Fly   737 NEVSVTSVQGEQNPVIEIVKELEQETISEVVPAQNDQSSVED--QTLADKENPVEKPS-PVK--- 795
            ||                             ||::....|||  :.:.|...|||..: ||:
Yeast   475 NE-----------------------------PAEDSNEPVEDSNKPVKDSNKPVEDSNKPVEDSN 510

  Fly   796 APSSSKDEPPAEENLPAPD-QDPIEQQKTPV------------AKNQQHDKEHNEAPKAESLSVS 847
            .|....::|..:.|.|..| .:|:|....||            .::|:.|.|....||..:.||:
Yeast   511 KPVEDSNKPVEDANEPVEDTSEPVEDAGEPVQETNEFTTDIASPRHQEEDIELEAEPKDATESVA 575

  Fly   848 DIPSS-SVTPSKKRNH-------------SSPANTPKKSKEIEALQSSVPRRALRSDKATPQNLR 898
            ..||: .|.|.:|.:.             |..:.|.:|::...:|:||    |:..::.|
Yeast   576 VEPSNEDVKPEEKGSEAEDDINNVSKEAASGESTTHQKTEASASLESS----AVTEEQET----- 631

  Fly   899 ESRSKRTLKTELTLLMDDTMRRSSPRLGRSPAESHSSHERSPMEKK 944
                     ||..:..||.:  |:....::...|:|:.:::...||
Yeast   632 ---------TEAEVNTDDVL--STKEAKKNTGNSNSNKKKNKKNKK 666

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)2-HP2	NP_610972.2	PspC_subgroup_1	<503..>842	CDD:468201	91/403 (23%)
		PTZ00449	<739..1091	CDD:185628	49/239 (21%)
		PTZ00108	<1132..1374	CDD:240271
		PRK05901	1624..>1822	CDD:235640
		PTZ00121	<1671..2360	CDD:173412
CHS5	NP_013434.1	Chs5_N	4..76	CDD:260117	6/29 (21%)
		fn3_2	77..165	CDD:435634	15/89 (17%)
		BRCT_CHS5_like	172..255	CDD:349373	19/91 (21%)
		PRK08581	290..>599	CDD:236304	82/352 (23%)
		rne	<446..618	CDD:236766	46/200 (23%)