Protein Alignment Su(var)2-HP2 and Rp1

DIOPT Version :9

• Sequence 1: NP_610972.2
• Gene: Su(var)2-HP2 / 36621
• FlyBaseID: FBgn0026427
• Length: 3257
• Species: Drosophila melanogaster
• Sequence 2: XP_008761780.1
• Gene: Rp1 / 681377
• RGDID: 1596713
• Length: 2150
• Species: Rattus norvegicus
• Alignment Length: 2158
• Identity: 412/2158 - (19%)
• Similarity: 729/2158 - (33%)
• Gaps: 545/2158 - (25%)

  Fly   264 ISTDTSRTTSVADTVTPVVSDDEGQEPQSELNQRHAN--DQESFLSS---------------TYE 311
            :|:..|.|.|.:.::..:.| .|||.|....|..|..  .:.||..|               :::
  Rat    22 VSSKMSETPSTSFSMIRLTS-SEGQVPSRHSNVTHPTVAKRISFYKSGDPQFGGVRVVVNPRSFK 85

  Fly   312 RLQSYLSNLSSAEPPPIYKKQNSARKSRSN-----EKKPSSSQQVKHANEQSAASDKEANKKERD 371
            ...:.|.|||...|.|...:..|..:.|.:     |.:...|....|..:.......:|.::.|
  Rat    86 TFDALLDNLSRKVPLPFGVRNISTPRGRHSITKLEELEDGESYVCSHNKKVLPVDLDKARRRPR- 149

  Fly   372 LEPPEASSSAKSSASKASGSRKLYDVANNATLEAVERM--------------------------S 410
               |..||.:.|:..|...:.............|..|:                          .
  Rat   150 ---PWLSSRSISTHVKLRSATATMPTTAPGLFRAPRRLVVFRNGDPKTRRVVLLSRRITQSFEAF 211

  Fly   411 LDLAEQIMEIDVERSYEFEKRSASKSRSL---SRSKIPADSSTSQLGHVR--------KLTYSSE 464
            |....|:|:..|.:.|..:.|.....:::   |.:.:.|.....:.|:..        ||...|.
  Rat   212 LQYLTQVMQYPVAKLYATDGRKVPSLQAVILSSGAVVAAGREPFKPGNYDIQKYLLPVKLPGISH 276

  Fly   465 RLDQPEPLGTQLRRSKSESLPKRGRPRGQKQRKNRGATMEEKSANC-RDGEGEPVKRKRGRPRKI 528
            |:.:......:.|:..:.|:|          |....:...||:.:| .|....|
  Rat   277 RVHRKGKAKIEKRKMSTHSVP----------RPQTDSLASEKTYDCFSDFSVAP----------- 320

  Fly   529 IPKEEAKTAETENTIESLNT-----NVPLSIDTSKENPETETVNLEVPIKQDELV-------SDL 581
               |.....||.:: ::|:|     .|..||..:::...|..:.:...||::.:.       :||
  Rat   321 ---ENYLALETHDS-QTLSTYPSEDGVEKSIVFNQDGTMTVVMKVRFKIKEETVKWTTTVNRADL 381

  Fly   582 DNAKELTGSTNLPQDDIEMASNHQETDLKCAPDRVALDKSESTPKVEEEQLCKVDTPSDTALDES 646
            .|..|.:..::.| ...|..|:..:..:.|:......|.::.....|||   ........||..|
  Rat   382 SNDDEKSKISSYP-GKTEDRSSSLKLVVPCSLSEDITDTTQQGSLTEEE---NTQMTEQQALSSS 442

  Fly   647 KVS-ESAKNHIELEDKDKDKEETQKESPNGNSKETNENSVI----VTNEVELPAKKAEAKAEAGN 706
            ... |:|...:.::...|..:...:....|..:...:.|||    |.:|.|:..|:...:.|. .
  Rat   443 SAGWENASMEVGIQGSQKQVKHFYRPPTPGPRRMRQKKSVIGTVTVVSETEVQEKQFSYREER-E 506

  Fly   707 IVEES---------------DSQLAEDFKLAEEILAAEVGK--------GVEANEVSVTSVQGEQ 748
            :.|:|               .::|.:.....|...|.|..|        .:.|..:.:||.:
  Rat   507 VGEKSKYHMFTHSCSKMSSVSNKLVQISSDDERESALERTKESGPLKSHAINAGAIEITSQR--- 568

  Fly   749 NPVIEIVKELEQETISEVVPAQNDQSSVEDQTLADKENPVEKPSPVK------APSSSKDEPPAE 807
                 ::|......::..||   :.|.||:.|   .::.:...:.:|      ..:.|.....|:
  Rat   569 -----VLKMCHNNALASTVP---ENSVVEEGT---DDSAISGKATIKHFRTCGNANDSFSSTTAD 622

  Fly   808 ENLPAPDQDPIEQQKTPVAKNQQHDKEHNEAPKAESLSVSDIPS--SSVT--------------- 855
            ..|.:                      .|..|...  ::|::||  |.|.
  Rat   623 TTLTS----------------------GNNCPNVR--TISEVPSVGSPVLTTGLVNEFAHCGLTE 663

  Fly   856 -PSKKRNHSSPANTPKKSKEIEALQSSVPRRALRSDKATPQNLRESRSKRTLKTELTLLMDDTMR 919
             |...|..|||..:.||.|..:.:.:|..::.:...|..|..:.:.....|: .::.||.|..
  Rat   664 HPGNGRQISSPFASKKKKKSQQRMITSKDKKKVIETKGIPNKVGKIHRAGTI-AQVVLLQDSG-- 725

  Fly   920 RSSPRLGRSPAESHSSHERSPMEKKVTVSKLAKDLITIDKE---KEIELKSLPDASETKDV---- 977
                                                .:|||   :|.||.:.|...|:.|:
  Rat   726 ------------------------------------GLDKEGRVREEELDTSPMVIESHDIFPKG 754

  Fly   978 --KITKTTTASDTSILTDENPSSSKTEMKKLKGKPLKAKKMSRTSETEVKKAIADSNEDIPSIFS 1040
              |.:|  ......:.|.:||.:.|. :.|.|.:|||.|.:....:.|.      ..||  .:|.
  Rat   755 NSKFSK--NFHKNKLNTVQNPKTQKL-LAKRKSRPLKIKSIGELRKQET------GQED--KVFL 808

  Fly  1041 IKCVEEHLTSSESEQKDEKEELLCPKPQIDCTNTDLEQS-TAIETDTE------------QVEEK 1092
                  |..|...|...||:.||.....::.....|.:| :.:||.||            :|.:.
  Rat   809 ------HSESKLCESNLEKQSLLHVFSSLEEDQKALHRSQSQVETVTENWKGMTKKSLVPKVNDL 867

  Fly  1093 RSNRRKSRRIRNEKFKTETDTLSDHLDAKKAENASLEISMRPKCT-------------LETQQSD 1144
            ....|..|:.:..|.|:.......|:..:....|||:   :|..|             ...|..:
  Rat   868 HVTVRNQRKQKGVKLKSGATVSEQHIATRADPLASLK---KPDLTEGIPHHSVKSYIQRWLQNIN 929

  Fly  1145 PVTAKNKRNSGRLSRKEKSVINAAKS--EKDKSPSAISQSTERKQLLNENPSKKDKKTEQSGNKK 1207
            |......|.|..|.:...:|:|...:  .::..|:.   |::.|..|.|:..:|.|.....|||.
  Rat   930 PYPDFEHRKSAPLGQDRSNVVNYNSNGFPENNLPTT---SSKGKSFLMESNKRKTKNANWKGNKN 991

  Fly  1208 EAVVGPLDKTETSSSTNIID------KKSNESFDSAMQPSDRLNQKESAFTKLSSISSP-KKIMK 1265
            :         |||.|..:.|      |.|.||.|.::..|......::.....:||:.| .|...
  Rat   992 Q---------ETSKSLVVKDNGEQPNKHSCESQDESLYDSYLGPLHDNCTLSQTSINDPCTKSHL 1047

  Fly  1266 DQDKDLDALSKGGDSNPTIRDTGED-----SRQTDKKHQENDTKHEEEDSSKLKANIDETKS--- 1322
            ..:|          |.|.::...::     .|||.:...:.||..|......|...:...::
  Rat  1048 STEK----------SRPEVKLVYQEMNFSTKRQTLEVAIQVDTMGENVPKDLLALLLQHLEAFIP 1102

  Fly  1323 SSEKDAEPISK--DSSQDSAKPRLSKPKSRNKRKK-----NEKKPNDSIAESDIEGGFQVNTETV 1380
            :::|....||:  .|..:...|......|.|....     |.|:..:|..:||           .
  Rat  1103 NNQKHQNGISQLPGSLAEVVFPSAIYNSSTNLLLAWLLVLNLKRNMNSFCQSD-----------A 1156

  Fly  1381 QATCSTPSESNK-KDMVKSDETNEEPNLSETEIGRIRKRGQAFHIENPKDDLHITPQNENQSIAG 1444
            ..|.|..||:.. .|::|.....||                       .|||.....|..:|
  Rat  1157 PKTTSRSSETAALLDVLKHVAITEE-----------------------ADDLKAAVANLVES--- 1195

  Fly  1445 VNFEKQVPLPESVESDT-PIMKIPTKTYLM--CTKNKTSLLSASEDPDIVLEPQKLITTSKGDSN 1506
               .|....|...|.|| |...|....:.:  |.:||::..|..::...|          :||..
  Rat  1196 ---TKTCSGPSGREQDTAPANCIAASLHSVDKCKENKSTQKSLLDEGYSV----------RGDCG 1247

  Fly  1507 PDL------DNANNLET-----SSTQDPK-EHEFSDQTFTDNSDIIPSCTKKSQIVFPTTPTKSS 1559
            |:|      ..:||..:     |.|..|| .:..:|..||.|.                :.|.|.
  Rat  1248 PELCVLEMVSKSNNTPSEGHTVSMTYPPKGVNNQNDALFTSND----------------SSTMSQ 1296

  Fly  1560 DQTKN-SFITPNRSPKSKRNVSKEAKRLDNSFEESQNAASESSASKVQKELRTPTASCRKLRVLI 1623
            ..|.| ||:.............|...:.||.:|          |:.:..|...|...|:.:..:.
  Rat  1297 RSTHNASFLGEACLLTDSLCSHKACAQKDNIYE----------AACLSDETHIPIRDCKTIEFVN 1351

  Fly  1624 KRTP--TSSLPTNSRKSIFKKTPAKSKRLTKILESMEKTPSREPSVSLGEVNPDSDPVAAESVAV 1686
            .:..  |.:|..........|.|   |.|..:.:|::|..| :.|.|...||..|......|...
  Rat  1352 SKENKCTDNLELTEEIKTVDKVP---KDLNILADSIDKNES-DISTSSQNVNKLSSQGIFLSKTH 1412

  Fly  1687 LHESDRDL----ESNEIPNEEVFEDTEEASAEDTDNKLKKKEDDHELEVNDICAASKNPITD-DS 1746
            | :||:|.    |....|.:::....:..|::..|:  :..|:...: .|.:.::.:|..:: :|
  Rat  1413 L-DSDKDYSPLEEFQNCPPKKIVNKKKSVSSDKEDS--RTSEEPRSI-TNSVTSSERNATSELES 1473

  Fly  1747 TKDASS-------------NKSTDSDVLQETKDELSNSLINATQGEDTPIKELTEEEVPNNKTVE 1798
            .:::.|             .|:....:.:|::..:|..|||.:.      :.:.|:...|...:|
  Rat  1474 FEESESQDTGIFNMKVRTEEKAAKESMQKESEARMSLELINISG------RNIIEQGRRNTAFLE 1532

  Fly  1799 DESKKQEILKDLEPDNAALEEDTASTAKAAEEMDLYIKEKSNVKSVLAEPETDVTDDEELAQSPI 1863
            ...:.|     :.|.:.....|  |.....:||.:. :.|..||.::...|.:...|..|..:..
  Rat  1533 TTGRGQ-----VTPPSLVFCYD--SNKNTEKEMSVG-ETKMRVKKIVDSMENESYTDSSLNCNKQ 1589

  Fly  1864 PNSSETTSVTDDPEPSTSSVVKRSLR-KREADSSQPDEAAKRKQRQDVEKSLTGKKEQVKP---- 1923
            ..|..|...:|....|.|....::|. :...|:.|..|..:...|:.:|| |.||.|.:||
  Rat  1590 HRSPGTLDWSDYGSDSESRYPCKALSYEHSDDTGQEREYPRGIVRRAIEK-LYGKAEIIKPPFFH 1653

  Fly  1924 --ARRRQLAEVE--ERPSLKRSK-TESEAKSTVQGKYISIIGNETIMSSTTAPIRETNREAASTS 1983
              ..:.|:....  |.|.:|::. .|||.:|.|..:.:|   ..::|.......|::..:|....
  Rat  1654 GSIHKSQVCPYNPVEVPCVKKTHFYESECQSLVSSEQVS---RSSLMLQEFQEERQSEVDANGMG 1715

  Fly  1984 PSARKSAVQEAKHVETTKHIILGPPGKKLLHSDSPAAEVKKPMVQTLLSSTLSLQKPSTLDDGSP 2048
            .|...|:::  |..:.::|      |:..:..                      :|...:|:|..
  Rat  1716 DSFGDSSIE--KVTKPSEH------GRVFMEK----------------------EKGKLIDNGKW 1750

  Fly  2049 LKIRKSL-KKSIADENIDGDQSIFSSSSVLNKNTSVVAPRKVNISVSLLQSKDTQVETAASSSET 2112
            |.....| :.|:.:..:.|:....|..::::|| |:..|..   ....|....|..|  .||||.
  Rat  1751 LLRENHLWRVSLDNPGMYGNADTTSVDTLMDKN-SIEVPYS---HFGELAPGPTMAE--LSSSEI 1809

  Fly  2113 PILTKKEKLK------TQKSTKKPEGNKKTESKKKSLVQGPQMKTQKSEEAVSGPKILNKYLKSE 2171
            ..:|:..::|      ...|..:|.|....:::          .|...:|     ||.|.:.:.:
  Rat  1810 EEMTQPLEVKCNYFNFPHGSDSEPFGEDFLDAQ----------NTNCPKE-----KIPNHHKEEK 1859

  Fly  2172 TES-SRKTVSTVT 2183
            ..| |.:|.:.||
  Rat  1860 RNSPSERTCTPVT 1872

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)2-HP2	NP_610972.2	MDN1	<596..845	CDD:227596	45/282 (16%)
		PTZ00449	<739..1091	CDD:185628	74/397 (19%)
		PTZ00108	<1132..1374	CDD:240271	56/278 (20%)
		PTZ00121	<1720..>2291	CDD:173412	96/496 (19%)
Rp1	XP_008761780.1	DCX	60..135	CDD:176357	14/74 (19%)
		DCX	182..257	CDD:176357	9/74 (12%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1181
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900