Protein Alignment Su(var)2-HP2 and Cp190

DIOPT Version :9

• Sequence 1: NP_610972.2
• Gene: Su(var)2-HP2 / 36621
• FlyBaseID: FBgn0026427
• Length: 3257
• Species: Drosophila melanogaster
• Sequence 2: NP_524359.2
• Gene: Cp190 / 41848
• FlyBaseID: FBgn0000283
• Length: 1096
• Species: Drosophila melanogaster
• Alignment Length: 1198
• Identity: 221/1198 - (18%)
• Similarity: 412/1198 - (34%)
• Gaps: 318/1198 - (26%)

  Fly    75 DRRRRPPSPSSSDESNDALEALFCGKSSQSKLSKRRERYESFDSVDDLGEALMRPSHRLTVPKPS 139
            :|::|||||                     |..:||       :|......|  |..|:..|.|.
  Fly   130 NRQQRPPSP---------------------KGIRRR-------TVGQPSSGL--PQQRVLGPSPQ 164

  Fly   140 TSQAGSKKSQDAAPHRSISNSSSSNIAMSSGQTYACPKNKKTNSVANKTAVSANGDKWASGKNKT 204
            :....:..:|.|...|   .|:.:.::.:||.:...|....:|.   |...::..::...|.|..
  Fly   165 SRNVATPIAQRANTQR---GSTGNTMSRTSGGSNRSPYGDSSNV---KQEPTSPFEQLRKGYNNN 223

  Fly   205 VTIVKPQKTD-LRPSRLEPKTDPL-----------NLGDLYGDSDS--DSSYEYESDFYGDQDSD 255
               .:|.:|. |.|...:|..:.:           .:...|||:|.  |....|:....||.|.|
  Fly   224 ---KRPAQTSLLSPPSKKPSLEEVKEFAEQQRMRKQIAAEYGDNDPEYDGGMLYDDVHAGDDDDD 285

  Fly   256 EEDEPVIDISTDTSRTTSVADTVTPVVSDDEGQEPQSELNQ-RHANDQESFLSSTYERLQSYLSN 319
            :                     :.|..|..:.|.||....| .|.       |:|.     .|..
  Fly   286 D---------------------MPPQPSTSKQQSPQGTQTQLEHG-------STTI-----ILKQ 317

  Fly   320 LSSAEPPPIYKKQNSARKSRSNEKKPSSSQQVKH-------------ANEQSAASDKEANKKERD 371
            .|.::.|.|..|.:|..|....:......:|..|             .|..:|.::|.|   ...
  Fly   318 DSPSQTPTIIVKDSSNAKLNHTKIIAEVLRQYPHIVKGHKNIKLKIMPNTPAAPTEKSA---PAT 379

  Fly   372 LEPPEASSSAKSSASKASGSRKLYDVANNATLEAVERMSLDLAEQIMEIDVERSYEFEKRSASKS 436
            ::||...|||.:|..|     ||:
  Fly   380 VKPPANQSSATTSPHK-----KLH----------------------------------------- 398

  Fly   437 RSLSRSKIPADSSTSQLGHVRKLTYSSERLDQPEPLGTQLRRSKSESLPKRGRPRGQKQR---KN 498
                 ....||.||..:...:|...|.::....:..|.|    .:.:.|.......||:|   |.
  Fly   399 -----VSFKADKSTPLITAQQKAASSQQKSGTSQTTGNQ----GTGANPPANTAAAQKRRIDSKT 454

  Fly   499 RGATMEEKSAN------C-RDG-EGEPVK--RKRGRPRKII--PKEEAKTAETENT-IESLNTNV 550
            ..|.:.:.:.|      | |.| .|.|:.  ..||..|.:|  .||....|..|:. ..|:| |.
  Fly   455 MHALIAQGAENTTGPWLCLRCGVNGRPISIPSYRGFRRHLINTHKETIDPALCEHCGWRSVN-NR 518

  Fly   551 PLSIDTSKENPETETVNLEVPIKQDELVSDLDNAK-ELTGSTNLPQDDIEMASNHQETDLKCAPD 614
            .|......|:   :|.:|.....:..|.:.....| ||....|    ::....|.|:. :.|
  Fly   519 ELHFHMYMEH---QTKSLLYTFAECALCNQSYRTKGELEAHIN----EVHTDDNKQQC-IYC--- 572

  Fly   615 RVALDKSESTPKVEEEQL----CKVDTPSDTALDESKVSESAKNHIELEDKDKDKEETQKESPNG 675
                      .||.|::|    .......:.||::..:.|:.:..:..:|::::.|..:::.|..
  Fly   573 ----------NKVFEQELQLYRHMKSYHKEQALEDGIIDETDEEFLGSQDEEEEAEGDEEQEPEQ 627

  Fly   676 NSKETNENSVIVTNEVELPAKKA--EAKAEAGNIVEESDSQLAEDFKLAEEILAAEVGKGVEANE 738
            ..|      |.:.:::.|||..|  ..:|:...:.||...|:.::.|..          |.:.||
  Fly   628 TGK------VRILSDISLPATSAITVQQAQQEQLQEEDVEQVQQEVKFV----------GADGNE 676

  Fly   739 VSVTSVQGEQNPVIEIVKELEQE----TISEVV------PAQNDQSSVEDQTLADKENPVEKPSP 793
            |.:|..|.:     ||:.:|.|:    |...||      .|::.:...::::||..|...:....
  Fly   677 VELTDEQRK-----EILSQLNQQQAGATAGGVVMVLSEPEAEHVKQETDEKSLAGTEEEYDDSQI 736

  Fly   794 VKAPSSSKDEPPAEENLPAPDQDPIEQQKTPVAKNQQHDKEHNEAPK--------AESL------ 844
            .....::.....|::|:....::.|:..:.......:.:::.|:.||        :|.|
  Fly   737 YSELGAADSVESAKKNIADESKESIDNLEWAENLIAESEEQSNKEPKSDKPRDDISEKLKELTGD 801

  Fly   845 --------SVSDIPSSSVTPSKKRNHSSPANTPKKSKEIEALQSSVPRRALRSDKATPQNLRESR 901
                    .|.|.|:::...|:..|........::..:|:.        ||:|....|:...|.:
  Fly   802 WTEDENDDDVDDKPATAELASELANKDPEPTVHEEEDDIDL--------ALQSLHKGPEEATEEK 858

  Fly   902 SKRTLKTELTLLMDDTMRRSSPRLGRSPAESHSSHERSPMEKKVTVSKLAKDLITIDKEKEIELK 966
            :..    |.....||.: .:.|.:...|       |:..::.:....|.:|..:.|.||.|:|..
  Fly   859 ASE----ESVTSADDAV-DAVPNINSQP-------EKMDVDSEAADEKASKAEVQIKKEAELEND 911

  Fly   967 SLPDASETKDVKITKTTTASDTSILTDENPSSSKTEMKKLKGKPLKAKKMSRTSETEVKKAIADS 1031
            ......|...:..:.:......::...|.......|...:: |.|..:.::...:.:.:|.|..|
  Fly   912 QEEFIKEDSPIPHSDSVAELREAVTASEGEDDVHLEADNIR-KELLDELIAEAEKPDQEKDIVQS 975

  Fly  1032 NEDIPSIFSIKCVEEHLTSSESEQKDEKEELLCPKPQIDCTNTDLEQSTAIETDTEQVEEKRSNR 1096
                         ||:.|:...::....|:.|.|..|:.....::::..|         ||.:..
  Fly   976 -------------EENATTEALDRSVTDEDDLVPPTQVSTEQMEIDEPAA---------EKAAEN 1018

  Fly  1097 RKSRRIRNEKFKTETDTLSDHLDAKKAENASLEISMRPKCTLETQQSDPVTAKNKRNSGRLSR-- 1159
            .:..|..:||...|           ...|.:.:::...|.|||:.:     |.::..||..:.
  Fly  1019 NEDTRTADEKEAVE-----------DKPNQTQDVTTAEKPTLESAK-----AGDEATSGEAASVD 1067

  Fly  1160 KEKSVINA-AKSEKDKSPSAISQSTERK 1186
            |.||:|:. ...::|:..:.:|.:.:.:
  Fly  1068 KVKSLISEWGDDDEDEDENGVSAAAKEE 1095

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)2-HP2	NP_610972.2	MDN1	<596..845	CDD:227596	49/286 (17%)
		PTZ00449	<739..1091	CDD:185628	62/383 (16%)
		PTZ00108	<1132..1374	CDD:240271	13/58 (22%)
		PTZ00121	<1720..>2291	CDD:173412
Cp190	NP_524359.2	BTB	20..122	CDD:279045
		BTB	31..127	CDD:197585
		C2H2 Zn finger	540..568	CDD:275371	6/31 (19%)
		C2H2 Zn finger	569..586	CDD:275371	5/30 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1181
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900