DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Su(var)2-HP2 and Muc18B

DIOPT Version :9

Sequence 1:	NP_610972.2	Gene:	Su(var)2-HP2 / 36621	FlyBaseID:	FBgn0026427	Length:	3257	Species:	Drosophila melanogaster
Sequence 2:	NP_001285431.1	Gene:	Muc18B / 32913	FlyBaseID:	FBgn0031000	Length:	308	Species:	Drosophila melanogaster

Alignment Length:	195	Identity:	46/195 - (23%)
Similarity:	69/195 - (35%)	Gaps:	41/195 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   498 NRGATMEEKSANCRDGEGEPVKRKR-GRPRKIIPKEEAKTAETENTIESLNTNVPLSID--TSKE 559
            |...:..||.|....|..|.|.... |...|:       |.|...|.|.:.|..|.:.:  |::.
  Fly    95 NLDESTTEKPATEAPGTTEKVTTAAPGTTEKV-------TTEAPGTTEKITTEAPGTTEKITTEA 152

  Fly   560 NPETETVNLEVPIKQDELVSDLDNAKELTGSTNLPQDDIEMASNHQETDLKCAPDRVALDKSEST 624
            ...||.:..|.|...:::.:      |..|:|..|..|....:....||   ||.  ..:|||:|
  Fly   153 PGTTEKITTEAPGTTEKITT------EAPGTTEKPATDAPGTTEKPATD---APG--TTEKSETT 206

  Fly   625 PKVEEEQLCKVDTPSDTALDESKVSESAKNHIELEDKDKDKEETQKESPNGNSKETNENSVIVTN 689
                       |.|..|  |:|.......:       :....||..:.||..:.|:.|.:.|..|
  Fly   207 -----------DAPGTT--DKSDTDAPITD-------EPSTAETSTDEPNTETTESGEETTIEDN 251

Fly 690 689
Fly 252 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)2-HP2	NP_610972.2	MDN1	<596..845	CDD:227596	22/94 (23%)
		PTZ00449	<739..1091	CDD:185628
		PTZ00108	<1132..1374	CDD:240271
		PTZ00121	<1720..>2291	CDD:173412
Muc18B	NP_001285431.1	CBM_14	26..72	CDD:279884
Muc18B	NP_001285431.1	MCLC	<77..177	CDD:283562	21/94 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1181
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900