DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Su(var)2-HP2 and CG34417

DIOPT Version :9

Sequence 1:	NP_610972.2	Gene:	Su(var)2-HP2 / 36621	FlyBaseID:	FBgn0026427	Length:	3257	Species:	Drosophila melanogaster
Sequence 2:	NP_001259282.1	Gene:	CG34417 / 31591	FlyBaseID:	FBgn0085446	Length:	5182	Species:	Drosophila melanogaster

Alignment Length:	4532	Identity:	830/4532 - (18%)
Similarity:	1424/4532 - (31%)	Gaps:	1550/4532 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 SAPTASS--AGVPRQRRISSDSSNSSSIDADIFQKLFHGKYLDDELLKEGSGSKSQDRRRRPPSP 83
            :||:.|:  :|.||:.:...|.::|.                     :..:|..||.|      |
  Fly   653 NAPSHSTPRSGSPRRSQPRDDYASSP---------------------RGPAGKPSQSR------P 690

  Fly    84 SSSDESNDALEALFCGKSSQSKLSKRRERYESFDSVDDLGEALMRPSHRLTVPKPSTSQAGS--- 145
            |::..|............::.:|.|.||        .|........|.|.:.|..||:..||
  Fly   691 SNTGGSTTTKTTTTSEPLTRRQLQKERE--------VDAAHRAFAASLRSSSPADSTTSVGSHHQ 747

  Fly   146 ------------KKSQDAAPHRSISNSSSSNIAMSSGQTYACPKNKKTNSVANKTAVSANGDKWA 198
                        ::......|.|.:.|.||.|:.::...:....|..:|::..||....   |.|
  Fly   748 TPRSSVSSNRTFRREMREGSHDSQAPSESSRISSTTVTRHTTGGNVTSNTIKTKTTKPV---KTA 809

  Fly   199 S----------GKNKTVTIVKPQKTDLRPSRLEPKT--DPLNLGDLYGDSDSD-SSYEYESDFYG 250
            |          |...|.|.....|:...|:...|.|  .|.:........|:. |.|.|.:...|
  Fly   810 SEPRSPTPKAGGSVTTTTTTITTKSSPSPAPASPTTAAPPTSAPASSAPPDNKLSQYTYTTTKPG 874

  Fly   251 DQDS-------DEEDEPVIDISTDTSRTTSVADTVTPVVSDDEGQEPQSELNQRHANDQESFLSS 308
            |..|       ...:||.:   |.|..||:...|.|...||:....|:
  Fly   875 DIFSLPPTTPPTINNEPTL---TTTRNTTTTTTTTTTATSDNLQNHPK----------------- 919

  Fly   309 TYERLQSYLSNLSSAEPPPIYKKQNSARKSRSNEKKPSSSQQVKHAN------EQSAASDKEANK 367
                 :|.:...:..:..||.|.:.||.:::..|:.|...:|.....      |...:|...|||
  Fly   920 -----KSAIEPATDTDSQPIRKVKLSANEAKVVEEAPCVRRQYYQLGNEGENPETPESSGTPANK 979

  Fly   368 KERDLEPPEASSSAKSSASKASGSRKLYDVANNATLEAVERMSLDLAEQIMEI------------ 420
            |...:..|......:...|..|.|.:...|....|.|. .|:|.|....|.|:
  Fly   980 KPHQMRRPHDEPEPQLRRSSKSPSVEPRQVQRETTFEG-RRVSQDREISIDELILIEETSGAPGS 1043

  Fly   421 -------------DVERSYEFEK-------------------------------------RSASK 435
                         ...||...||                                     ||..|
  Fly  1044 PKIPSPRAQSPGKPATRSQSPEKPQPRATPRQSPEKEQPAFKQTHEVYTPSQPEKQFPRARSPEK 1108

  Fly   436 S----------RSLSRSKIPADSSTSQLGHVRKLTYSSERLDQ---PEP----LGTQL-----RR 478
            :          |.....::|...|..::..||:.:.|..:..:   |:|    .|..|     |:
  Fly  1109 TPGWTQPQVSPRQSPEKQLPRAQSPEKVPAVRQPSVSPRQSPEKQIPDPKTRDQGPGLPRISPRQ 1173

  Fly   479 SKSESLPK----RGRPRGQK--------------------QRKNRGATMEEKSANCRDGEGEPVK 519
            |..:.|||    :.|...:|                    |::......||...|.||.:.:|:.
  Fly  1174 SPEKQLPKDVPQKSRQSPEKDLTNQQRREEEIFRSTITTTQKRTTNNLNEEFITNERDNQNQPIS 1238

  Fly   520 RKRGRPRKIIPKEEAKTAETENTIESLNTNVPLSIDTSKENPETETVNLEVPIKQDE-------- 576
            .|:.:    ||.......:...||||.:...|......:..||.:    |.|..:.:
  Fly  1239 EKKPQ----IPANAEPNTKPSETIESPDGGFPSKTTEVEAQPEVK----ESPTYRKKGLTRRETF 1295

  Fly   577 ---------LVSDLDNAKELTGSTNLPQDDIEMASNHQET-----------DLKCAPDRVA---L 618
                     :..|.|.....|...|..|:|:.::....||           |....|.||.   :
  Fly  1296 EDRCRQILGMEEDGDTQGTYTERPNNEQEDVNVSHTTIETIQVKIEDCPNDDEDDKPRRVTETYV 1360

  Fly   619 DKSESTPKVEEEQLCKV-----------------------------DTPSDTALDES-------- 646
            .:::...|||||....|                             :||.....|:.
  Fly  1361 VRTQPKIKVEEELFVDVTEAEDVEILVNPSKKSPKEEDSPKYPKGPETPKSPRNDQRIPSIPKKG 1425

  Fly   647 ------KVSESAKNHIELEDKDKDKEETQ--KESPNGNSKE-------TNENSVIVTNEVELPAK 696
                  |..|:.:...|.|...|:.|.:|  ||||. |.||       ..|.::::|.|......
  Fly  1426 QSPVQFKTEETPRYPQEQERYPKEPETSQYPKESPR-NPKEDAETININEETTIVITKEGSKSPS 1489

  Fly   697 KAEAKAEAGNIVEESDSQLAEDFKLAEEILAAEVGKGVEANEVSVTSVQGEQNPVIEIVKELEQE 761
            ...:.:....:.:...............:...::...||:|.|:...:......|:|.:.: ...
  Fly  1490 PRWSPSPERRVPKSQQPPSPTASPSVSPVSGRKIPNEVESNFVTEKIIDCRGKTVVEKISQ-RPR 1553

  Fly   762 TISEVVPAQNDQSS---------VEDQTLADKENPVEK-----------------------PSPV 794
            |.|...|.:|.:.|         .|.:...|.|:..:|                       |.|:
  Fly  1554 TPSPTTPKKNTKPSQKIPERVPETESEPEKDSESETKKTTSVSVTKTETERRNSRTTKTKQPLPL 1618

  Fly   795 KAPSSS--KDEPPAEENLPAPDQDPI--------------------------------------- 818
            |.|.|.  ..:.|.:::|....:|.:
  Fly  1619 KEPQSKVPAGKSPRKDSLTGRKRDSLVEETRITTTTTTTRQGRKPSDTNGSPSIKDRLRSSPRKQ 1683

  Fly   819 ----EQQKTPV---AKNQQHD-------------KEHNEAPKAESLSV-SDIPSSSVTP----SK 858
                :|.:||.   .:|.:.|             :..||..::.::|| ::|....:.|    ::
  Fly  1684 KTSPQQTRTPTPAQTRNPEDDVDGDSSSPDASPTRVGNERRRSSNISVHTEIIIDHMAPKSPKTE 1748

  Fly   859 KRNHSSPANTPKKSKEI---EALQSSVPRRALRSDKATPQNLRESRSKRTLK-------TELTLL 913
            :|:.....|.|...:::   |..:|:...|..|.|||  :.:..|.|:..:|       .|::.|
  Fly  1749 RRSQGGTGNVPSPIRKLPVTERKESAPVPRVTRRDKA--EKVTRSTSENIIKMSGTKPHPEMSSL 1811

  Fly   914 -------------MDDTMRRSSPRLGRSP---------AESHSSHERSPMEKKVTVSKLAKDL-- 954
                         ...|:..|..|:..:.         .::.||.|.||  .::..:.:..:|
  Fly  1812 KPGGDRSRPSKCCTTKTINLSEQRINTATDIEGVIIDIQQAKSSREPSP--DRIVPTPVPAELET 1874

  Fly   955 ------------------------ITIDKEK------------------EIELKSLPDASETKDV 977
                                    |.|.:|:                  |:::...|.....|.:
  Fly  1875 GKPRYPDVVQEPDDEPRRKPQVTNIPIFEEESQTYVGCQISELHSSNGIEVDILDNPTVEAPKSL 1939

  Fly   978 KITKTTTASDTSILT-DENPSSSKTEMKKLKGKPL--------------------------KAKK 1015
            .....|..:|.|:|: .|..|......:|:|...:                          |..|
  Fly  1940 DYPVNTPDTDESLLSVHEKVSRFTHSAEKVKEPKVSAPFSREFDVNAKIPENDDCLLSINQKVDK 2004

  Fly  1016 MSRTSETEVKKAIADSNEDI--PSIFSI-------KC---------------------------- 1043
            ..||:|..::.....|..:|  |.:..|       .|
  Fly  2005 FLRTAENVIRPTSLPSRPEIERPGLEEIDEELLRDDCTLSVSQKVHKFIDTAEKLAPTMPQKSPR 2069

  Fly  1044 ----VEEHLT-SSESEQK-DEKEELLCPKPQIDCTNTDLE---QSTAIETDTE------------ 1087
                :|.|:: .||.|:: ||:.|     |::| .:||:|   |::.:||:.|
  Fly  2070 LVANIERHISRQSEPERELDEESE-----PELD-RDTDVEDDDQTSQLETEEEITQTVTKKETLK 2128

  Fly  1088 ----QVEEKRSNRRKSRRIRNEKFKTETDTLSDHLDAKKAENASLEI-SMRPKCTLETQQSDPVT 1147
                |.:|.|..||.|        |.|.:.|.......|.:..|..: ..:.|.:.:..|.:|
  Fly  2129 EFKQQTKETRETRRDS--------KAEPEKLQKKSPQTKVKEESARVPKYQAKVSQKVSQWEP-- 2183

  Fly  1148 AKNKRNSGRLSRKE------KSVINAAKSEKDK----SPSAISQSTERKQLLNENPSKKDKKTEQ 1202
            .|..:...::::||      |..::..|.|.:|    .|....:.::.|  |.|.|.:..|||.|
  Fly  2184 KKQPQREPKVTQKETPLEPKKQPLSKVKDEPEKVNKREPKVPQKESQTK--LKEEPERVTKKTPQ 2246

  Fly  1203 SGNKKEAVVG------------------PLDKTET------------------------------ 1219
            ...:||.:..                  |:.||.|
  Fly  2247 KEPRKEPLRQSEDEPEFSPEEEFDDEPLPMTKTHTTAIEMKRQKDILNRPSVFGQRTPERKSSTT 2311

  Fly  1220 -------------SSSTNII--DKKS-------------NESFDSAMQPSDRLNQKESAFTK-LS 1255
                         |.|||:|  :|:|             .::..||..|:.....|.::.:| :.
  Fly  2312 PSPTKLNGTRGRPSPSTNLITEEKRSYRNQVTNVSKPGTRKTTPSANSPAQSPPPKTTSISKRME 2376

  Fly  1256 SISSPKKIMKDQDKDLDALSKGGDSNPTIRDTGEDSRQTDKKHQENDTKHEEEDSSKLKANIDET 1320
            .||....:::|.|.|::.:.....|:.:.:..|:....|..:......  ....|.:...|::.|
  Fly  2377 QISQQSWVVQDVDVDVEVVGPAPPSHISEKPQGKSPSPTSSRSLSRSP--SRSPSRRTSTNLNTT 2439

  Fly  1321 KSSSEKDAEPISKDSSQDSAKPRLSKPKSRNKRK-KNEKKPNDSIAESDIEGGFQVNTETVQATC 1384
            .:::....|..|      :.|....||.|.|..| :.|..|.:|:.|..|...:..|| |.:...
  Fly  2440 STNTTTTTEHPS------TIKTTTPKPTSTNPSKDEPEIIPIESLTEKSITTTYTTNT-TGRNVA 2497

  Fly  1385 STPS--ESNKKDMVKSDETNEEPNL---SETEIGRIRK------RGQAFHIENPKDDLHITPQNE 1438
            |..:  |...:..|.|:.|...|:.   :::.:..||:      :.......:.:||..:.|:|.
  Fly  2498 SRRNVFEPVHETHVDSEPTGRRPSYMDHTKSSLEHIRRDSLEINKSHYSRKSSMEDDSPVEPRNP 2562

  Fly  1439 NQSIAGVNFEKQVPLPESVE-SDTPIMKIPTKTYLMCTKNKTSLLSASEDPDIVLEPQKLITTSK 1502
            |.|   |.|:  ||...|.. :|.|              .||||....||.|:.||.:::.
  Fly  2563 NSS---VKFD--VPRKSSSRGADEP--------------RKTSLKGKDEDSDLELEIEEIF---- 2604

  Fly  1503 GDSNPDLDNANN-LETSSTQDPKEHEFSDQTFTDNSDI-IPSCTKKSQIVFPTTPTKSSDQTKNS 1565
                 ||..... |||.::.:.:....:.......:.| ..:.|..:.|...|||.|||...|
  Fly  2605 -----DLQRLEKLLETVASYEMRRRIRAQMRLIRKNMINAGTTTTITTITTSTTPGKSSPLPK-- 2662

  Fly  1566 FITPNRSPKSKRNVSKEAKRLDNSFEESQNAAS------------------------ESSASKVQ 1606
             |..::||.....|..:..|...|..:.|....                        |.|||..|
  Fly  2663 -IRRDQSPAGAAEVKTKEVRTTTSRRQQQQRVEQVDSTTPIAPGKTSPHGKPPVKPRERSASPAQ 2726

  Fly  1607 KELRTP----TASCRKLRVLIKRTPTS--------------------------SLP-TNS---RK 1637
            |...:|    :...|......|.|.||                          ::| ||.   ||
  Fly  2727 KRRISPPGKQSPGDRSTTTTTKVTTTSTTRGAPSKPAQGPIWADRSKVLKGHATVPQTNGSTPRK 2791

  Fly  1638 SIFKKTPAKSKRLTKILESMEKTPSREPSVSLGEVNPDSDPVAAE-SVAVLHESD------RDLE 1695
            .....|.:.|.::|:.:.|...|.|...:.:......:.|.:.:. .|....|:.      |.|:
  Fly  2792 GSTSSTTSSSGKITRTMTSSSTTTSSSSTTNTRNKQREEDSITSSYGVGPTDENGLPLFGIRALK 2856

  Fly  1696 SNEI-PNEEVFEDTEEASA---ED---TDNKLKKKEDDHELEVN---DICAASKNPITDDSTKDA 1750
            .... |.||..|..:|.:.   |:   :|||...:.:..||..:   |..||.|..:.|:   |.
  Fly  2857 KKATPPAEEPCETKQEVTGYVIEEQFYSDNKSPPRHERKELIYSSNADELAAIKQQLQDE---DD 2918

  Fly  1751 SSNKSTDSDVLQETK--------------------DELSNSLINATQGEDT--PIKELTEEEVPN 1793
            ||....|:.|::|.|                    .|||...|.......|  ....:.:..|.:
  Fly  2919 SSPPLLDARVVREFKKVESQQSLPEDARYVRRGSVKELSEKFIRKESSSSTHSTHSSIAQSLVRH 2983

  Fly  1794 NKTVEDESKKQEILKDLE-PDNAALEEDTASTAKAAE---------------EMDLYIKEKSNVK 1842
            ....||:|:..::...:| |.....:..|.||.:::.               .:|..::...|..
  Fly  2984 EDETEDDSESNDVCSVIEAPQMRQNQSHTMSTTRSSNTRSFLNSSADQRQVTSVDDVLERMRNAD 3048

  Fly  1843 SVLAEPETDVTDDEEL----------------AQSPIP-----------------------NSSE 1868
            :|  |...|.::|.|.                .:|.:|                       .|..
  Fly  3049 NV--EEPGDSSEDREARALLNKFLGASVIMQGVESMLPPTATGQRLNSQGVKTTRITNTYSKSGN 3111

  Fly  1869 TTSVTDDPEPSTSSVVKRSLRKREADSSQP------------DEAAKRKQRQDVEKSLTGKKEQV 1921
            :||.|::...:|:.|         :.||.|            ||   :..:|.:|::.|.::.:.
  Fly  3112 STSTTNNTSNTTNKV---------SSSSAPVTRTTCDIEEIWDE---QVLKQLLEQASTYEERRK 3164

  Fly  1922 KPARRRQL-AEVEERPSLKRS-KTESEAKSTVQGKYISIIGNETIMS---STTAPIRETNREAAS 1981
            ..||.|:| ||.||:.:||:: |.|.|.:.:...:|..||...|..|   ....|.:|..::...
  Fly  3165 IRARLRELMAEREEQKNLKQAPKEEKEEEESSASEYEEIIEEVTDYSDEEEEVPPKKEEPKKEEV 3229

  Fly  1982 TSPSARKSAVQEAKHVETTKHIILGPPGKKLLHSDSPAAEVKKPMVQTLLSSTLSLQKPSTLDDG 2046
            |.....|..|...:..|..:..:     ||:..:::..::..:.:.:.|....|:....|:..||
  Fly  3230 TKKEVTKKEVTTKQQEEIQQKAV-----KKVEKTETKTSQATESVSKKLAKVELASSSSSSTTDG 3289

  Fly  2047 SPLKIRKSLKKSIADENIDGDQSIFSSSSVLNKNTSVVAPRKVNISVSLLQSKDTQ-------VE 2104
            ..:: .:||..........|.....||||:.::.:|.::..:|:   ::::::|..       ..
  Fly  3290 VQVQ-GESLPAKATKTGATGAAGPVSSSSIGSRKSSSLSSSQVS---TVVRARDKAKPEMMPVAG 3350

  Fly  2105 TAASSSETP------------ILTK------------------KEKLKTQKSTKKPEGNKKTESK 2139
            |.:.|...|            :.:|                  ::.|:.|..:...|.|:....:
  Fly  3351 TGSGSESVPGSGAPNTGSRLSVPSKEDSGTESGEDLRLLAAGLRDTLQQQSGSDASEANRSLVEE 3415

  Fly  2140 --------KKSLVQGPQM-------------------------------KTQKSEEAV------- 2158
                    :.||.||.::                               ||.:.::.|
  Fly  3416 VTDALSRLESSLKQGKELAVDGGQRQALLGLVARLQSGLSAPEKLAEDRKTDECQKEVETGSPEP 3480

  Fly  2159 SGPKILNKYLKSETESSRKTVST-----VTGRKQIGQLEVLKKPE---SRKSEESLVEA-ISRKK 2214
            .|....:::.|....:||.||..     ...|:.:..:.:|:..:   |:....|.|.. :.|..
  Fly  3481 DGDSRQSRFAKRRQRNSRHTVGVSREELADARRYMEDMLILEGKDFALSKTPSSSAVPVQLYRPN 3545

  Fly  2215 Q--SQVQRLSKIDGRKSEGTSLPQPDVSKSETALKAALPKETEFPVQDAEIE-----KMSKGRGH 2272
            |  :|.|:...::.:.:...:||..:.|:.........|...::.|..|..|     :.|...|:
  Fly  3546 QFVAQSQQPQSVNNQPNATQALPTQNQSQLRPNTSNRRPLSGDYAVSFASYEANQNSQNSSPEGN 3610

  Fly  2273 QNAVKNTKTEQPKSKPKTEV----RSLQAEAAT--------ELMDSMDSQSDVSD---------- 2315
            .|:..|:::....|...:..    :.|...|.|        :.|...||.||:.|
  Fly  3611 GNSASNSQSNSNSSSNSSRFGGGKKHLMKRANTIDIPKAKAKYMADCDSDSDLEDDHGPHLGLKR 3675

  Fly  2316 -------------IRATFPESQ------GIFNVPGHMT---------RAISS------------- 2339
                         :....|:::      ...|...|.|         |::|:
  Fly  3676 AVQVSVKRRVHNAVPPFEPKTENDHKFLAFINKQSHQTGLGWSGGGGRSVSNWTHKFGNIKHTFE 3740

  Fly  2340 NRSLA------PTPTP---------------------MSDSQRNASKERFTPVSDQKKPIRES-- 2375
            ..:.|      |.|.|                     |...|....:.:......:::.:||.
  Fly  3741 TGAAATVTKGKPPPVPGHVPGWAKQEQLHHQQLQREQMQREQMQREQYQREQRQREQRELREQLQ 3805

  Fly  2376 -QTLSKRRARGGRNQPLVSKRKAGEAE-------DGTAVINPKRPREMDEEDHPQ---------- 2422
             :...:.:::..:||..:|||:..:.|       ....:...|..||..:.:..|
  Fly  3806 REQYQREQSQRDQNQRELSKREQFQREQLQREQLQREQLQREKLQREQLQREQLQREQLQREQLQ 3870

  Fly  2423 ----QNDHVQESAFAAFPVKI----TAASSVIPQVVRSTGNTVPQNIS-------PRKLCVKINR 2472
                |.:.:|........:::    .||::|  |:.|.....:.:.:.       .|:...::.|
  Fly  3871 REQLQREQLQREQLQRDQLQLQQQQQAAAAV--QIERQRRQELERQLRLEQEARFEREERTRLER 3933

  Fly  2473 RPYNKWLRSTQ---------ERNEEQEGSRNVTSLPLLGETSETDSAAE-----SMSESI---LQ 2520
            ..|.:.|:..|         :|.::::..|.......|....:.:.||:     ...:|:   ::
  Fly  3934 EYYEQQLQRQQVERQQQLDRQRQQQEQMERQRRQEMELRLQQQREQAAQVNNFIHAPQSVFRPIE 3998

  Fly  2521 SQVQSEPAI--------QPLPA--------SQPDSCTLQASDLRIRESSAQLAPIAAYDSPAAND 2569
            ::.|.:|.|        ||.||        |||.           ::|...|.|      .:|..
  Fly  3999 NETQPQPGIYKPIAHKSQPNPAVWKPPTQQSQPP-----------QQSQQHLQP------RSATT 4046

  Fly  2570 SSTSPALDIAPESAQTAKATLNTALCPSTEK-------HLPDEPTLLESSKKVAEP--------- 2618
            .|.:|    :|.|..|:...|.....|..:.       |..:|.:|.::.::..:|
  Fly  4047 YSNTP----SPSSTATSPIGLPWVAKPKVDNSDFRRKAHHFEERSLRDNIEQQQQPTYPNGNNGY 4107

  Fly  2619 -QKLQTFQAKCLPVPIPEVKSEPEDIMDEHSPNEPMPMVAAAP-----ATPQPHAIT---EDAGP 2674
             |:..:.::|. |. :.|.|..|.      .||...|..||.|     |.|.|..|:   .|..|
  Fly  4108 LQRHNSLRSKA-PA-LSEFKKRPS------LPNAMDPGTAAPPRQVYQAPPPPTNISFTYADFPP 4164

  Fly  2675 ----------------------DTIQ--VNTLG---VSTSSRPLELH----------SIPSASDP 2702
                                  |.::  .|.||   |.|||.|..|.          |.|...|.
  Fly  4165 VRRPQGASAHNYRSQPCLTSAVDQVEALTNPLGAPLVLTSSNPTYLPPPGSRRFDYISSPVDVDA 4229

  Fly  2703 DGNPNAIGQTKMYSFLYPKRYKQSYDDVGLDFCCPNLDGPMRAIDFTRLHSKAEVPVLEIPQ--- 2764
            |..||:  .|...:...|.....:.|| .||     ||.     |...|..:||..|:..|:
  Fly  4230 DSPPNS--PTSFMTMPNPTLMTDNTDD-DLD-----LDS-----DNNMLEYRAETKVMRKPRSQT 4281

  Fly  2765 -FLVITTKFISKADKNMPSK-VRAKLELLDKSKE-------------------------RDSSKL 2802
             ..|...:....:|..:..| .||...||...|:                         ..|..|
  Fly  4282 AVRVADRRNAHMSDDEVYGKNSRAAKSLLYTMKQLGGGPGNASVGNSGQRRQPLTAPSSPKSGCL 4346

  Fly  2803 TPTA---TTPTADPTGP--SSFSP--------APASVGPATQPFPSI-------------IQN-- 2839
            :|..   ..|..:|..|  |:|.|        :|.|..||.. .|||             .||
  Fly  4347 SPDGRPYQAPLVEPLFPQLSTFEPKRQPQFANSPMSTPPAVS-MPSINYQANPTYTPPRSNQNSN 4410

  Fly  2840 ----------LLSAPLPDPGLFNHPTTVDPSTS-----TPVVSGSSSS---------------TT 2874
                      :::.||.|.|....|.::..|.|     |...|.:|||               |.
  Fly  4411 SYLGETNTSYVVTYPLDDSGDEPEPESMATSVSQRLRRTSEHSNASSSLSLGSTSWTANPVHNTV 4475

  Fly  2875 ISADLDS----------------------------------LSKQLPR--GTKLIKKSVQQVATN 2903
            .|..|||                                  |..|||:  ..:|.|:..||:...
  Fly  4476 PSVPLDSAMGPPVDRSTKPQVSQPVGPKMPQHVAQKQIPQQLPNQLPQQIPQQLPKQLPQQIPQQ 4540

  Fly  2904 PSLAGTSMVINASPSFIQLPPICPNDKQRVELQARVQMFDLVLQ---TLSRRAANLSVAERQRTI 2965
            ........:....|.  |:||..|.     :|..::...:|..|   .|.|.|..||  .|..||
  Fly  4541 LPQQLPQQLPKQLPQ--QIPPQLPK-----QLPQQIPQPELPQQLPNNLPRHAPKLS--SRSHTI 4596

  Fly  2966 E----------------------EIVRTSSLMAIDV--------DVGTKLLENYVHYLNKAT--- 2997
            :                      .|:.:::...:..        ::..|.|.|.:....::|
  Fly  4597 QGDSGYENRPLQNRVMSQQTLNSSIITSNNHTTVQKQQKEQHINELRRKSLGNVLESSQRSTYFE 4661

  Fly  2998 ----STMTPLTPAQINSSL--------------------------------GASTSSTLSKSIAT 3026
                |:..|.||..:.|||                                |.|.|:|.|.:...
  Fly  4662 QEYKSSAPPDTPDIVKSSLPKEDAPLLKKFGPPQRHHYMPNSYQSPQLNKQGNSNSTTTSSTSVR 4726

  Fly  3027 SDIPQQGKKISADHAQQRSSL---PAT----IPLYDGGRNTLGFPYSCSKSTAGRKS----SYVA 3080
            |....|.:.....|.|.:.|:   |||    :|..|...:.:.|....:.::..|::    |:..
  Fly  4727 STTVVQQQHHQQQHQQIKPSIVETPATPQPQVPPEDEIPHNIVFNNVSAFTSMSRRNHEEDSHQG 4791

  Fly  3081 TST------------------------PVKASTSQAAAAAALGNAQPRSTLGIPKSVRE--DASQ 3119
            |.:                        |..|..:|..:...|...:...:|.:||....  |.:|
  Fly  4792 TQSGSRVNRLSKCDSWNQICQLQQTAGPSPAKYNQPGSPGELRRTKSGHSLAVPKLYEAGIDKAQ 4856

  Fly  3120 FVNLNTTVCMPAPRTNAKKKPGTSGPLKSMNSSPAVQKPALCKQQTAPARTLSKSTVSSVARAKS 3184
            ......||   |...:.:|.| |.|.::.:.:|   .......:::|..||.:...:|:.|| ||
  Fly  4857 VSEKQRTV---AAYFSGQKSP-TGGQVEELRTS---MTTTTSSRKSAINRTKTSEKLSAAAR-KS 4913

  Fly  3185 TGSLSAVLGETPADEFVSPAGMSLSTTGNPNVFIINHAVQSEESILP 3231
            ..||:     |.::..||.||:.:...|.....|...|..|..:.:|
  Fly  4914 LSSLT-----TTSNGNVSTAGLGMVVRGGGVGGIGGGAALSRSATMP 4955

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)2-HP2	NP_610972.2	MDN1	<596..845	CDD:227596	63/407 (15%)
		PTZ00449	<739..1091	CDD:185628	97/614 (16%)
		PTZ00108	<1132..1374	CDD:240271	61/329 (19%)
		PTZ00121	<1720..>2291	CDD:173412	134/766 (17%)
CG34417	NP_001259282.1	Smoothelin	2594..2636	CDD:289290	8/50 (16%)
		Smoothelin	3127..3176	CDD:289290	13/51 (25%)
		GBP_C	<3810..3882	CDD:303769	12/71 (17%)
		coiled coil	3857..3868	CDD:293879	1/10 (10%)
		CH	5076..5179	CDD:237981
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1181
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900