DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Su(var)2-HP2 and Ibsp

DIOPT Version :9

Sequence 1:	NP_610972.2	Gene:	Su(var)2-HP2 / 36621	FlyBaseID:	FBgn0026427	Length:	3257	Species:	Drosophila melanogaster
Sequence 2:	NP_032344.2	Gene:	Ibsp / 15891	MGIID:	96389	Length:	324	Species:	Mus musculus

Alignment Length:	250	Identity:	57/250 - (22%)
Similarity:	104/250 - (41%)	Gaps:	46/250 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   555 DTSKENPETETVNLEVPIKQDELVSDLDNAKELTGSTNLPQDDIEMASNHQETDLKCAPDRVALD 619
            |:|:||.:.::...|.  :::|..::.:|.::..|:    :|....|.|   :.|.......|..
Mouse    65 DSSEENGDGDSSEEEG--EEEETSNEEENNEDSEGN----EDQEAEAEN---STLSTLSGVTASY 120

  Fly   620 KSESTPKVEEEQLCKVDTPSDTALDESKVSESAKNHIELEDKDKDKEETQKESPNGNSK-ETNEN 683
            .:|:||:.:..:|..:..|......||:..       ::::.|:::||.::|..|.|.: |.:||
Mouse   121 GAETTPQAQTFELAALQLPKKAGDAESRAP-------KVKESDEEEEEEEEEEENENEEAEVDEN 178

  Fly   684 SVIV----TNEVELPAKKAEAKAEAGNIVEESDSQLAEDFKLAEEILAAEVGKGVEANEVSVTSV 744
            .:.|    ||..|:......:..:.|   ||::         |||....|.|.........:|||
Mouse   179 ELAVNGTSTNSTEVDGGNGSSGGDNG---EEAE---------AEEASVTEAGAEGTTGGRELTSV 231

  Fly   745 QGEQNPVIEIVKELEQ-----ETISEVVPAQNDQSSVE-----DQTLADKENPVE 789
             |.|..|  ::...:|     |......|.....|:||     :||..:..|..|
Mouse   232 -GTQTAV--LLNGFQQTTPPPEAYGTTSPPIRKSSTVEYGGEYEQTGNEYNNEYE 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Su(var)2-HP2	NP_610972.2	MDN1	<596..845	CDD:227596	48/208 (23%)
		PTZ00449	<739..1091	CDD:185628	15/60 (25%)
		PTZ00108	<1132..1374	CDD:240271
		PTZ00121	<1720..>2291	CDD:173412
Ibsp	NP_032344.2	BSP_II	17..321	CDD:283165	56/249 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	60..228		41/190 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	243..263		3/19 (16%)
		Cell attachment site. /evidence=ECO:0000255	293..295
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1181
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900