DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tra2 and safb

DIOPT Version :9

Sequence 1:	NP_476764.1	Gene:	tra2 / 36619	FlyBaseID:	FBgn0003742	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_999848.1	Gene:	safb / 321979	ZFINID:	ZDB-GENE-030131-698	Length:	855	Species:	Danio rerio

Alignment Length:	299	Identity:	66/299 - (22%)
Similarity:	107/299 - (35%)	Gaps:	85/299 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 SASSSSAGTTSSGHKDRRSDYD-----------YCGSRRHQRSSSRRRS--------RSRSSSES 67
            ||.:.:|..|  |.:|..|..|           .|.|.....||..:.|        :|.....|
Zfish   307 SAQADNASET--GLRDIESAVDSEMASKGEAVEECKSTDPAESSEVKESSVQGDDQKKSEEEDAS 369

  Fly    68 PPPEPRHRSGRSSRDRERMHKSREHPQASRCIGVFGLNTNTSQHKVRELFNKYGPIERIQMVIDA 132
            ..||.:...|.:|              :.|.:.|.||::.|....::.||:|||.:...::|.:|
Zfish   370 TKPESKDDKGGAS--------------SGRNLWVSGLSSTTRATDLKNLFSKYGKVVGAKVVTNA 420

  Fly   133 QTQRSRGFCFIYFEKLSDARAAKDSCSGIEVDGRRIRVDFSITQRAHTPTPGVYLGRQPRGK--A 195
            ::..:|.:.|:....:.:|..........|:.||.|.|:.:..:.|         |::|..|  |
Zfish   421 RSPGARCYGFVTMCSIEEATKCISHLHRTELHGRMISVERAKNEPA---------GKKPADKNDA 476

  Fly   196 PRSFSPRR------------------------GRRVYHDRS-ASPYDNYRDRYDYRNDR-YDRNL 234
            .:|.|.||                        .|.|..|:| ..|..:.:.:...|:.: .|||
Zfish   477 KKSVSDRRLSSDSKTDKSENKDEKTEGDGKGGERTVVMDKSKGEPVISLKTKSKERSSKSRDRN- 540

  Fly   235 RRSPSRNR----------YTRNRSYSRSRSPQLRRTSSR 263
              |.|:.|          ..|.|...|.|..::|....|
Zfish   541 --SLSKERKDILSFDQIKEQRERERQRQREREIREVERR 577

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tra2	NP_476764.1	RRM	<74..242	CDD:223796	42/195 (22%)
tra2	NP_476764.1	RRM_TRA2	98..175	CDD:240809	19/76 (25%)
safb	NP_999848.1	SAP	19..53	CDD:128789
safb	NP_999848.1	RRM_SAFB1_SAFB2	384..459	CDD:241123	19/74 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1765
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940