Protein Alignment tra2 and RBMX

DIOPT Version :10

• Sequence 1: NP_476764.1
• Gene: tra2 / 36619
• FlyBaseID: FBgn0003742
• Length: 264
• Species: Drosophila melanogaster
• Sequence 2: NP_002130.2
• Gene: RBMX / 27316
• HGNCID: 9910
• Length: 391
• Species: Homo sapiens
• Alignment Length: 159
• Identity: 48/159 - (30%)
• Similarity: 68/159 - (42%)
• Gaps: 32/159 - (20%)

  Fly   103 GLNTNTSQHKVRELFNKYGPIERIQMVIDAQTQRSRGFCFIYFEKLSDARAAKDSCSGIEVDGRR 167
            ||||.|::..:..:|.|||.|..:.::.|.:|.:||||.|:.||..:||:.|....:|..:||:.
Human    14 GLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARDMNGKSLDGKA 78

  Fly   168 IRVDFSITQRAHTPTPGVYLGRQPRGKAPRSFSPRRGRRVYHDRSASPYDNYRDRYDYRNDRYDR 232
            |:|:       ....|....||:.....|||..|.||.|.....|.
Human    79 IKVE-------QATKPSFESGRRGPPPPPRSRGPPRGLRGGRGGSG------------------- 117

  Fly   233 NLRRSPSR------NRYTRNRSYSRSRSP 255
            ..|..|||      ..|:.|.:.|.||.|
Human   118 GTRGPPSRGGHMDDGGYSMNFNMSSSRGP 146

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tra2	NP_476764.1	RRM_TRA2	96..175	CDD:409798	27/71 (38%)
RBMX	NP_002130.2	RRM_RBMX_like	7..86	CDD:409816	27/78 (35%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	61..391		29/112 (26%)
		dnaA	165..>306	CDD:455861
		RBM1CTR	173..217	CDD:400429
		Necessary for the association to nascent RNAPII transcripts and nuclear localization	186..236
		Necessary for RNA-binding	333..391