DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tra2 and HNRNPA3

DIOPT Version :9

Sequence 1:	NP_476764.1	Gene:	tra2 / 36619	FlyBaseID:	FBgn0003742	Length:	264	Species:	Drosophila melanogaster
Sequence 2:	NP_001317178.1	Gene:	HNRNPA3 / 220988	HGNCID:	24941	Length:	378	Species:	Homo sapiens

Alignment Length:	122	Identity:	41/122 - (33%)
Similarity:	66/122 - (54%)	Gaps:	6/122 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 PPPEPRHRSGRSSRDR-ERMHKSREHPQASRCIGVFGLNTNTSQHKVRELFNKYGPIERIQMVID 131
            ||..|:..|||..|.| |..|..:| |:..|.:.:.||:..|:...:||.|.|:|.:....::.|
Human     6 PPGRPQPDSGRRRRRRGEEGHDPKE-PEQLRKLFIGGLSFETTDDSLREHFEKWGTLTDCVVMRD 69

  Fly   132 AQTQRSRGFCFIYFEKLSDARAAKDSCS-GIEVDGRRIRVDFSITQRAHTPTPGVYL 187
            .||:|||||.|:.:..:.:..||  .|: ..:||||.:....::: |..:..||.:|
Human    70 PQTKRSRGFGFVTYSCVEEVDAA--MCARPHKVDGRVVEPKRAVS-REDSVKPGAHL 123

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tra2	NP_476764.1	RRM	<74..242	CDD:223796	38/116 (33%)
tra2	NP_476764.1	RRM_TRA2	98..175	CDD:240809	24/77 (31%)
HNRNPA3	NP_001317178.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..35		12/29 (41%)
		RRM1_hnRNPA_like	36..113	CDD:409992	24/79 (30%)
		RRM2_hnRNPA3	126..205	CDD:409996
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	204..225
		HnRNPA1	331..>347	CDD:402981
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	336..378
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910