Protein Alignment tra2 and HNRNPA1L2

DIOPT Version :10

• Sequence 1: NP_476764.1
• Gene: tra2 / 36619
• FlyBaseID: FBgn0003742
• Length: 264
• Species: Drosophila melanogaster
• Sequence 2: NP_001011724.1
• Gene: HNRNPA1L2 / 144983
• HGNCID: 27067
• Length: 320
• Species: Homo sapiens
• Alignment Length: 143
• Identity: 37/143 - (25%)
• Similarity: 59/143 - (41%)
• Gaps: 37/143 - (25%)

  Fly    71 EPRHRSGRSSRDRERMHKSREHPQASRCIGVFGLNTNTSQHKVRELFNKYGPIERIQMVIDAQTQ 135
            ||:....|....|...|.:      .:.|.|.|:..:|.:|.:|:.|.:||.||.|:::.|..:.
Human    85 EPKRAVSREDSQRPGAHLT------VKKIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSG 143

  Fly   136 RSRGFCFIYFEKLSDARAAKDSCSGIEVDGRRIRVDFSITQRAHTPTPGVYLGRQ-------PRG 193
            :.|||.|:.|:.       .||            ||..:.|:.||     ..|..       |:.
Human   144 KKRGFAFVTFDD-------HDS------------VDKIVIQKYHT-----VKGHNCEVRKALPKQ 184

  Fly   194 KAPRSFSPRRGRR 206
            :...:.|.:||||
Human   185 EMASASSSQRGRR 197

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tra2	NP_476764.1	RRM_TRA2	96..175	CDD:409798	22/78 (28%)
HNRNPA1L2	NP_001011724.1	Globular A domain	4..94		3/8 (38%)
		RRM1_hnRNPA1	12..92	CDD:410154	2/6 (33%)
		Globular B domain	95..185		29/119 (24%)
		RRM_SF	105..184	CDD:473069	27/102 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	181..216		6/17 (35%)
		RNA-binding RGG-box	218..240
		HnRNPA1	255..292	CDD:463312
		Nuclear targeting sequence. /evidence=ECO:0000250	268..305
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	271..320