Protein Alignment tra2 and RBM7

DIOPT Version :10

• Sequence 1: NP_476764.1
• Gene: tra2 / 36619
• FlyBaseID: FBgn0003742
• Length: 264
• Species: Drosophila melanogaster
• Sequence 2: NP_001272974.1
• Gene: RBM7 / 10179
• HGNCID: 9904
• Length: 267
• Species: Homo sapiens
• Alignment Length: 308
• Identity: 61/308 - (19%)
• Similarity: 101/308 - (32%)
• Gaps: 108/308 - (35%)

  Fly    19 RRTRKRLYELAERIPGPFDYPLIGSMLLT-IGKS----------PLELVTHLMELMHHLPSPMR- 71
            ||.|:.     :....||..|...|..:: ||.|          |.::...::::..||.:|.|
Human   129 RRERRE-----QAAAAPFPSPAPASPAISVIGVSAGGHTLSRPPPAQVPREVLKVQTHLENPTRY 188

  Fly    72 ---------------AWLGPFL----LVVVDRPEMVQDVLSSPDCVQKPFMYDFFRLSKGLFGAP 117
                           ..|||.|    |.....|...|. |.:|:...          :.|..|
Human   189 HLQQARRQQVKQYLSTTLGPKLASQALTPPPGPSSAQP-LPAPETAH----------ATGPTG-- 240

  Fly   118 ADQWKRHRKLLNASFSPAALKSFVPTLNAKADQFTRELAGKVSGECFDVHKLLARYTLVTISSTT 182
                       :|..||.||.    |:.:.::   :||  .|||...||:......|.....|.:
Human   241 -----------SAPNSPMALL----TIGSSSE---KEL--PVSGNLLDVYSSQGVATPAITVSNS 285

  Fly   183 LGADLSVEKREVLEEYTSNAIQMFTNCFERIYKAWLHPDCVYRMTAAFREEEVRFKSFKQMSRKI 247
            ..|:|...|||:.|.                           ...|..:|.:      |:.:..:
Human   286 CPAELPNIKREISET---------------------------EAKALLKERQ------KKDNHNL 317

  Fly   248 ITMRQA--LLSETKQTKTEYQQDSDPE---ENQELPKAKI-FIERLEE 289
            |..|:.  :....|:..|...:.:|||   ....:.||.: :|.:|::
Human   318 IERRRRFNINDRIKELGTLIPKSNDPEMRWNKGTILKASVDYIRKLQK 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tra2	NP_476764.1	RRM_TRA2	96..175	CDD:409798	15/78 (19%)
RBM7	NP_001272974.1	RRM_RBM7	9..83	CDD:410005
		ZCCHC8 binding. /evidence=ECO:0000269|PubMed:27905398, ECO:0007744|PDB:5LXR, ECO:0007744|PDB:5LXY	25..35
		ZCCHC8 binding. /evidence=ECO:0000269|PubMed:27905398, ECO:0007744|PDB:5LXR, ECO:0007744|PDB:5LXY	59..76
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	163..267		27/136 (20%)