Protein Alignment RpI1 and RpIIIC160

DIOPT Version :9

• Sequence 1: NP_523743.1
• Gene: RpI1 / 36617
• FlyBaseID: FBgn0019938
• Length: 1642
• Species: Drosophila melanogaster
• Sequence 2: NP_001096987.2
• Gene: RpIIIC160 / 32524
• FlyBaseID: FBgn0030687
• Length: 1383
• Species: Drosophila melanogaster
• Alignment Length: 1709
• Identity: 458/1709 - (26%)
• Similarity: 732/1709 - (42%)
• Gaps: 434/1709 - (25%)

  Fly     5 RAMDVHMFPSDLEFAVFTDQEIRKLSVVKVITGITFDALGHAIPGGLYDIRMG-SYGRCMDPCGT 68
            ||..::...|.::|.:....||::.::|::|:...:.|....:|.|:.|.||| |....|  |.|
  Fly     7 RASALNKKISHVQFGISGADEIQQEALVRIISKNLYQAQRQPVPYGVLDRRMGISTKDAM--CET 69

  Fly    69 CLK-LQDCPGHMGHIELGTPVYNPFFIKFVQRLLCIFCLHCYKLQMKDHECEIIMLQLRLIDAGY 132
            |.: |.:|.||.|:::|..||::....:....:|.:.|..|..:.:|..:.::...:|...:..|
  Fly    70 CGQGLNECIGHFGYLDLALPVFHIGHFRSTINILQMICKVCAHVMLKPEDRQLYEKKLHNPNFSY 134

  Fly   133 IIEAQELELFKSEIVCQNTENLVAIKNGDMVHPHIAAMYKLLEKNEKNSSNSTKTSCSLRTAITH 197
                    |.|..:                   |:    ::|.|.:|               :|
  Fly   135 --------LGKKAL-------------------HV----QMLAKAKK---------------VT- 152

  Fly   198 SALQRLGKKCRHC-------NKSMRFVRYMHRRLVFYVTLADIKERVGTGAETGGQNKVIFADEC 255
                    ||.||       .|....::.:|         ...|.|......|...|:::.:.:.
  Fly   153 --------KCPHCGSPNGGVKKGPGLLKILH---------DPYKGRKMDSLFTSNMNEMLRSTQT 200

  Fly   256 RRYLRQIYANY---PELLKLLV-------PVLGLSNTDLTQGDRSPVDLFFMDTLPVTPPRARPL 310
            .|.|.....||   .||..|:|       |...::...:...|..|..|..  |....||.....
  Fly   201 NRDLNSTLGNYSTAEELTPLMVLDLFEQIPQRDVALLGMCSHDAHPKHLIV--TRVFVPPACIRP 263

  Fly   311 NMVGDMLKGNPQTDIYINIIENNHVLNVVLKYMKGGQEKLTEEAKAAYQTLKGETAHEKLYTAWL 375
            :::.::..|..:.|:.:...|...:.:|:.::|..|.              |.|..||.    |.
  Fly   264 SVLSEVKAGTTEDDLTMKQSEILLINDVIQRHMATGG--------------KIELIHED----WD 310

  Fly   376 ALQMSVDVL-------LDVNMSREMKSGEGLKQIIEKKSGLIRSHMMGKRVNYAARTVITPDPNI 433
            .||:.|.:.       :.:||:.: |:..|:.|.::.|.|..|.::.||||:::.||||:||||:
  Fly   311 FLQLHVALYFHSEISGIPINMAPK-KTTRGIVQRLKGKQGRFRCNLSGKRVDFSGRTVISPDPNL 374

  Fly   434 NVDEIGIPDIFAKKLSYPVPVTEWNVTELRKMVMNGPDVHPGANYIQDK-NGFTTYIPADNASKR 497
            .::::|:|...||.|:||..|...|:..:|::|.|||.:||||||:|.: :.|..|:...|   |
  Fly   375 MINQVGVPVRVAKILTYPERVNPANIRHMRELVRNGPSMHPGANYVQQRGSSFKKYLAYGN---R 436

  Fly   498 ESLAKLLLSNPKDGIKIVHRHVLNGDVLLLNRQPSLHKPSIMGHKARILHGEKTFRLHYSNCKAY 562
            |.:|:.|    |.| .:|.||:.:||::|.||||||||.|||.|:|:: ..::|||.:...|..|
  Fly   437 EKVAQEL----KCG-DVVERHLRDGDIVLFNRQPSLHKMSIMCHRAKV-QPQRTFRFNECACTPY 495

  Fly   563 NADFDGDEMNAHYPQSEVARAEAYNLVNVASNYLVPKDGTPLGGLIQDHVISGVKLSIRGRFFNR 627
            ||||||||||.|.||:|.|||||..|:...||.:.||:|..|....||.:..|..|:.:..|..:
  Fly   496 NADFDGDEMNLHLPQTEEARAEALILMGNQSNLVTPKNGEILIAATQDFITGGYLLTQKEVFLTK 560

  Fly   628 EDYQQLV--FQGLSQLKKDIKLLPPTILKPAVLWSGKQILSTIIINIIPEGYERINLDSFAKI-- 688
            |:..||.  |.........|||.||.:|||..||:|||:.|.::         |.|.||..::
  Fly   561 EEAMQLAACFLANEDSTMHIKLPPPALLKPRRLWTGKQMFSLLM---------RPNDDSQVRLNM 616

  Fly   689 AGKNWNVSRPRPPICGTNPEGNDLSESQVQIRNGELLVGVLDKQQYGATTYGLIHCMYEL----Y 749
            ..|..|.:|.: .:|.        ::|.:.|||.||:.||:||...|:   |...|::.|    :
  Fly   617 VNKGRNYTRNK-DLCS--------NDSWIHIRNSELMCGVMDKATMGS---GTKQCIFYLLLRDF 669

  Fly   750 GGDVSTLLLTAFTKVFTFFLQLEGFTLGVKDILVTDVADRKRRKIIRECRNVGNSAVAAALELED 814
            |...:|..:....::.::|||..||:.|:.|:..:       :|:::
  Fly   670 GESHATKAMWRLARIASYFLQNRGFSFGISDVTPS-------KKLLQ------------------ 709

  Fly   815 EPPHDELVEKMEAAYVKDSKFRVLLDRKYKSLLDGYTNDINSTCLPRGLI--------------- 864
               |.||:  :...|.|.:        :|..||...|......|.|...:
  Fly   710 ---HKELL--LNNGYAKCN--------EYIELLKAGTLQCQPGCTPEETLESVMLRELSAIREQA 761

  Fly   865 --TKF----PSNNLQLMVLSGAKGSMVNTMQISCLLGQIELEGKRPPLMISGKSLPSFTSFETSP 923
              |.|    |:|:..:|.|||:|||.:|..|:...:||..:.|||.|.....::||.|......|
  Fly   762 AKTCFAELHPTNSALIMALSGSKGSNINISQMIACVGQQAISGKRVPNGFENRALPHFERHSAIP 826

  Fly   924 KSGGFIDGRFMTGIQPQDFFFHCMAGREGLIDTAVKTSRSGYLQRCLIKHLEGLSVHYDLTVRDS 988
            .:.||:...|.:|:.|.:||||.|||||||:||||||:.:|||||.|:|.||.|.||||.|||::
  Fly   827 AARGFVQNSFYSGLTPTEFFFHTMAGREGLVDTAVKTAETGYLQRRLVKCLEDLVVHYDGTVRNA 891

  Fly   989 DNSVVQFLYGEDGLDILKSKFFNDKFCADFLTQNATAILRPAQLQLMKDEEQLAKVQRHEKHIRS 1053
            .|.:|..:||.||||.:..:           |:|     :|..|....|..:....|..::.:.:
  Fly   892 VNEMVDTIYGGDGLDPVSME-----------TRN-----KPVDLVHQYDNLRAQHPQGKDRPLNA 940

  Fly  1054 WEKKKPAKLRAAFTHFSEELREEVEVKRPNEINSKTGRRRFDEGLLKLWKKADAEDKALYRKKYA 1118
            .|..:..:.......|: |.|::.::...|.||  |..:|..:                .:|:|.
  Fly   941 EEMSEALETLLRTPEFA-EARDDFKLDVRNHIN--TVSKRIGQ----------------LQKRYE 986

  Fly  1119 RCPDPTVAVYKQDLYYGSVSERTRKLITDYAKRKPALKETIADIMRV--KTIKSLAAPGEPVGLI 1181
            :|.|              :..:...|.|:         :.:..:.|:  :..:::..||..||.|
  Fly   987 KCID--------------LCHQIECLTTE---------QLLQFVRRINDRYNRAVTEPGTAVGAI 1028

  Fly  1182 AAQSIGEPSTQMTLNTFHFAGRGEMNVTLGIPRLREILMLASSNIKTPSMDIPIKPGQQHQ-AEK 1245
            ||||||||.|||||.||||||...||:|.|:||:.||:. |:..|.||.:...::.....: |.:
  Fly  1029 AAQSIGEPGTQMTLKTFHFAGVASMNITQGVPRIVEIIN-ATKTISTPIITAELENCHSMEFARQ 1092

  Fly  1246 LRINLNSVTLANLLEYVHVSTGLTLDPERSY---EYDM-RFQFLPREVYKEDYGVRPKHIIKYMH 1306
            ::..:...|||.|..||.|..|    |...|   ..|| |.:.|         |:   ||
  Fly  1093 VKARIEKTTLAELSSYVEVVCG----PYSCYLAIGVDMARIKLL---------GL---HI----- 1136

  Fly  1307 QTFFKQLIRAILKVSNASRTTKIVVIDDKKDADKEDDNDLDNGDEVGRSKAKANDDDSSDDNDDD 1371
              ....::.:|||.....:.|::.|:..:.
  Fly  1137 --DLDTIVFSILKSRMRVKPTQVEVVASQS----------------------------------- 1164

  Fly  1372 DATGVKLKQRKTDEKDYDDPDDVEELHDANDDDDEAEDEDDEEKGQDGNDNDGDDKAVERLLSND 1436
                                                                             
  Fly  1165 ----------------------------------------------------------------- 1164

  Fly  1437 MVKAYTYDKENHLWCQVKLNLSVRYQKPDLTSIIRELAGKS------VVHQVQHIKRAIIYKGTD 1495
                               .:.||.:....::|..|||..:      ||..:.:|.||:|  ..|
  Fly  1165 -------------------RIVVRVEATRTSTINAELARLALSLQNVVVAGLPNINRAVI--AVD 1208

  Fly  1496 DDQLLKT-----DGINIGEMFQHNKILDLNRLYSNDIHAIARTYGIEAASQVIVKEVSNVFKVYG 1555
            |.:...|     :|..:.::.....::. .|..||:|..|.:|.|||||..:|:.|::.|.:.:|
  Fly  1209 DARQPPTYKLCIEGYGLRDVIATYGVVG-KRTRSNNICEIYQTLGIEAARTIIMSEITEVMEGHG 1272

  Fly  1556 ITVDRRHLSLIADYMTFDGTFQPLSRKGM-EHSSSPLQQMSFESSLQFLKSAAGFGRADELSSPS 1619
            ::||.||:.|:|..||..|....::|.|: :...|.....|||.:...|..||.:|:.|.::..|
  Fly  1273 MSVDWRHIMLLASQMTARGEVLGITRHGLAKMRESVFNLASFEKTADHLFDAAYYGQTDAINGVS 1337

  Fly  1620 SRLMVGLPVRNGTGAFELL 1638
            .|:::|:|...|||.|:||
  Fly  1338 ERIILGMPACIGTGIFKLL 1356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RpI1	NP_523743.1	RNA_pol_rpoA1	14..1009	CDD:274106	314/1050 (30%)
		RNAP_I_RPA1_N	18..982	CDD:259844	300/1019 (29%)
		RNA_pol_Rpb1_5	936..1593	CDD:282807	168/675 (25%)
		HMG-box	1057..1119	CDD:294061	10/61 (16%)
		RNAP_I_Rpa1_C	1166..1638	CDD:132722	118/488 (24%)
RpIIIC160	NP_001096987.2	PRK08566	13..919	CDD:236292	317/1076 (29%)
		RNAP_III_RPC1_N	24..889	CDD:259847	302/1019 (30%)
		RNA_pol_Rpb1_5	839..1304	CDD:282807	167/668 (25%)
		RNAP_III_Rpc1_C	1013..1353	CDD:132723	117/485 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466353
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0086
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	293	1.000	Inparanoid score	I87
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D11825at50557
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm51395
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR19376
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.900