Protein Alignment CG12869 and Ces1h

DIOPT Version :9

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_001357759.1
• Gene: Ces1h / 75704
• MGIID: 1922954
• Length: 562
• Species: Mus musculus
• Alignment Length: 639
• Identity: 160/639 - (25%)
• Similarity: 253/639 - (39%)
• Gaps: 192/639 - (30%)

  Fly    16 ILIHLS-----------PYISAQQTHIKLEQGDLIGLKVFPDGTRGAVYAFLGIPYAQAPINELR 69
            ||:.||           |.::.  ||     |.::|..:..:|....|..|||:|:|:.|:..||
Mouse     7 ILLSLSAMAWGGYPSSPPVVNT--TH-----GKVLGKYISLEGFTQPVAVFLGVPFAKPPLGSLR 64

  Fly    70 FAPAKPSSSFNRTLQATTMQPLCPQ---LANTIYDESSDGSMPRSVSTDEDCLYLNIWTPESGMR 131
            |||.:|...::....||:..|:|.|   |...:.|...:......:...|||||||::||...|:
Mouse    65 FAPPQPPEPWSFVKNATSYPPMCSQDAVLGQMVNDLIINNKEKIRLRFSEDCLYLNVYTPVDLMK 129

  Fly   132 -YGKLPIVV------IVTGEEFAYDWPRNRINGLDL-AGEGIVVVSVQYRNNIYGWLSLGEQHRN 188
             ..:||::|      :|.|...|||       |..| |.|.:|||::|||..|:|:.|.|::|..
Mouse   130 NTNRLPVMVWIHGGGLVVGGASAYD-------GRTLSAHENVVVVTIQYRLAIWGFFSTGDEHSR 187

  Fly   189 VPGNYGLSDVQMALRWIRRNADAFGGNPDHITLLGHGSGG--------APLA------------L 233
              ||:|..|...||.||:.|...|||:|..:|:.|..:||        :|||            :
Mouse   188 --GNWGHLDQLAALHWIQDNIANFGGDPGSVTIFGQSAGGESVSVLVLSPLAKNLFHRAISQSGV 250

  Fly   234 VAT----LEDSSQVKQLVLMSPGPIMRALGQNHQKWIVETGQVLVQKLGCQFEEAQRRQLMGCLR 294
            |.|    :||:|.|.:.:.::.|            ....|..|:|.                |||
Mouse   251 VFTSGLFMEDASSVTEQIAVTAG------------CKTTTSAVIVH----------------CLR 287

  Fly   295 RKSREDLLRAYESV------------YNHGNGSSQL-GVILPEGLPLEQRLRNKTLPPVLLGITS 346
            :|:.|:||...:.:            .|:....:.| ||:||:........:|....|.::||..
Mouse   288 QKTEEELLEIMQKMNLFKLDAQENTKKNYPFLPTVLDGVVLPKAPEAILAEKNFNTVPYIVGINK 352

  Fly   347 NE-----------------------GAFLQD--YWLDVAREG-QVALHKYINHTLLPNVMRALES 385
            .|                       ..||:.  |:.::..:| .||:.||              |
Mouse   353 QEFGWTLPMIMEFPPTDVKLDKKVISLFLRKLAYFFNIPEDGIPVAIEKY--------------S 403

  Fly   386 VGEESSTQLAAIRWRYFNGKGEGVSHLLAGMQRLLSESLYELPYSRILELLN---GTTSYAYVFD 447
            .|.:...|...  |                :.:|:.:.::.:| |.|:...:   |..:|.|.|.
Mouse   404 KGTDDPIQNRV--W----------------LLQLIGDVMFGIP-SVIVSRGHRDAGAPTYMYEFQ 449

  Fly   448 HSHSMDMRGRRNLFGGASHSSDLPLLLGPSLFQQIARRRFSGEEEQLCRKIRGAFANFIKNGNPT 512
            ...|.....:.....| .|..::..:.|    ..|.|...|.||..|.:.:...:|||.:||||.
Mouse   450 SRPSFSSELKPKTVTG-DHGDEVYSVFG----APILREGSSEEEINLSKMMMKFWANFARNGNPN 509

  Fly   513 PGRIYDGWLPYNKENPFVYSLG---EQA-----------------KTPQTGSVD 546
             |:....|..||::..:: .:|   :||                 |.||||..:
Mouse   510 -GQGLPHWPEYNQKKGYL-QIGATTQQAQGLKDKEVSLWTELRAKKPPQTGHTE 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	151/610 (25%)
Ces1h	NP_001357759.1	COesterase	24..546	CDD:365897	151/605 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910