Protein Alignment CG12869 and Ces2f

DIOPT Version :10

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_001073334.2
• Gene: Ces2f / 71903
• MGIID: 1919153
• Length: 561
• Species: Mus musculus
• Alignment Length: 598
• Identity: 150/598 - (25%)
• Similarity: 238/598 - (39%)
• Gaps: 153/598 - (25%)

  Fly    13 LLPILIHLSPYISAQQTHIK-LEQGDLIGLKVFPDGTRGAVYAFLGIPYAQAPINELRFAPAKPS 76
            ||.:|:|:....|::.:.|: ...|.:.|..|.....:...:.|||||:|:.|:..|||||.:..
Mouse    17 LLVLLLHVKGLDSSEASPIRNTHTGQVRGKFVHLTDIKAGAHNFLGIPFAKPPVGPLRFAPPEAP 81

  Fly    77 SSFNRTLQATTMQPLCPQLANTIYDESSDGSM-------PRSVSTDEDCLYLNIWTPESGMRYGK 134
            ..::.....|:...:|.|..:.:   :.:|..       |.|:|  ||||||||:||........
Mouse    82 EPWSGVRDGTSQPAMCLQNDDIV---NLEGLKIIKMILPPFSMS--EDCLYLNIYTPAHAQEGSN 141

  Fly   135 LPIVV------IVTGEEFAYDWPRNRINGLDLAG-EGIVVVSVQYRNNIYGWLSLGEQHRNVPGN 192
            ||::|      :|.|....||       |..||. |.:|||..|||..|.|:.|.|::...  ||
Mouse   142 LPVMVWLHGGGLVAGMASMYD-------GSVLAATEDVVVVVTQYRLGIPGFYSTGDEQAR--GN 197

  Fly   193 YGLSDVQMALRWIRRNADAFGGNPDHITLLGHGSGGAPLALVATLEDSSQVKQLVLMSPGPIMRA 257
            :|..|...||.|:::|...||||||.:||.|..:||.          |.....|..:|.|...||
Mouse   198 WGFLDQTAALHWVQQNIANFGGNPDSVTLFGQSAGGT----------SVSFHVLSPVSQGLFHRA 252

  Fly   258 LGQNHQKWIVETGQVLVQKL----------------GCQFEEAQRRQLMGCLRRKSREDLL---R 303
                    |:|:|..|:..:                ||  |.:....|:.|||.||..::|   :
Mouse   253 --------IMESGVALLPTIIPDSPEMIFTKVANLSGC--ETSNSEALVRCLRGKSEAEILAMSK 307

  Fly   304 AYE--------------------SVYNH------GNGSSQLGVILPEGLPLEQRLR--NKTLPPV 340
            |:.                    |...|      |..:.:.|.|:|:.....|.:|  |:.....
Mouse   308 AFRFMPAVVDGKFLPRHPKKLLASADFHPVPSIIGVNNDEYGWIIPKIFKFSQTIRKINRNNLKA 372

  Fly   341 LLGITSNEGAFLQDYWLDVAREGQVALHKYINHTLLPNVMRALESVGEESSTQLAAIRWRYFNGK 405
            ::.||:.:.....:.       |.:.:.:|:..|..|                     |.
Mouse   373 IMKITTEQMMLPSEC-------GDLLIEEYLRDTEDP---------------------WT----- 404

  Fly   406 GEGVSHLLAGMQRLLSESLYELPYSRILELLNG-TTSYAYVFDHSHSMDMRGRRNLFGGASHSSD 469
                  |....:.::.:.|..:|..::...... ...|.|.|.|..|: ::..|.....|.|..:
Mouse   405 ------LQMQFREMIGDFLIIIPALQVARFQRSHAPVYFYEFQHRSSL-LKYFRPWHVKADHGDE 462

  Fly   470 LPLLLGPSLFQQIARRRFSGEEEQLCRKIRGAFANFIKNGNPTPGRIYDGWLPY----NKENPFV 530
            |.|:.| |.|..: :..|:.||:.|.||:...:|||.:.|||....     |||    |:::.::
Mouse   463 LYLIFG-SFFWGL-KFSFTAEEKLLSRKMMKYWANFARYGNPNSED-----LPYWPASNQDDLYL 520

  Fly   531 Y-----SLGEQAK 538
            .     |:|...|
Mouse   521 QLDIHPSVGHALK 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	145/584 (25%)
Ces2f	NP_001073334.2	COesterase	32..540	CDD:395084	145/583 (25%)