DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG12869 and Ces2j

DIOPT Version :9

Sequence 1:	NP_001369085.1	Gene:	CG12869 / 36616	FlyBaseID:	FBgn0033943	Length:	839	Species:	Drosophila melanogaster
Sequence 2:	XP_038953911.1	Gene:	Ces2j / 685645	RGDID:	1591368	Length:	576	Species:	Rattus norvegicus

Alignment Length:	521	Identity:	146/521 - (28%)
Similarity:	234/521 - (44%)	Gaps:	93/521 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 QQTHIKLEQGDLIGLKVFPDGTRGAVYAFLGIPYAQAPINELRFAPAKPSSSFNRTLQATTMQPL 91
            :.||....:|..:.:|    .|:..::.|||||:|:.|:..|||||.:....::....||:...:
  Rat    54 RNTHTGQVRGSFVHVK----DTKSGIHTFLGIPFAKPPVGPLRFAPPEDPEPWSGVRDATSQPAM 114

  Fly    92 CPQLANTIYD---ESSDGSMPRSVSTDEDCLYLNIWTPESGMRYGKLPIVVIVTGEEFAYDWPRN 153
            |.|.|....:   |:....:|.|    ||||||||:.|........||::|          |
  Rat   115 CLQTAMMNLEGMKETELTKLPMS----EDCLYLNIYVPAHAHEDSNLPVMV----------W--- 162

  Fly   154 RINGLDLAG--------------EGIVVVSVQYRNNIYGWLSLGEQHRNVPGNYGLSDVQMALRW 204
             |:|..|.|              |.||:||:|||..:.|:.|.|:||..  ||:|..|...||||
  Rat   163 -IHGGGLVGGSASMNDASTLAATEEIVIVSIQYRLGVLGFFSTGDQHAR--GNWGYLDQMAALRW 224

  Fly   205 IRRNADAFGGNPDHITLLGHGSGGAPLALVATLEDSSQVKQLVLMSPGPIMRALGQNH----QKW 265
            :::|...||||.|.:|:.|..:||..:        ||.|  :..||.|...||:.|:.    ...
  Rat   225 VQQNIAYFGGNRDSVTIFGVSAGGTSV--------SSHV--VSPMSKGLFHRAIMQSGVALLPGL 279

  Fly   266 IVETGQVLVQKL----GCQFEEAQRRQLMGCLRRKSREDLLRAYESVYNHGNGSSQLGVILPEGL 326
            |.:|.:|:.:.:    ||:..:::  .|:.|||.||::::| |...|:....|... |..||:.
  Rat   280 ISDTSEVVYKTVANLSGCEASDSE--ALIRCLRAKSKQEIL-AINQVFKMIPGVVD-GKFLPKH- 339

  Fly   327 PLEQRLRNKTLPPV--LLGITSNE-----GAFLQDYWL--DVAREG-QVALHKYINHTLLPNVMR 381
            | ::.|.:|...||  ::|:.::|     ...|..|.:  ::.||. ..||.......:||  ..
  Rat   340 P-QELLASKDFHPVPSIIGVNTDECGWGVPTILGLYHIINNITRETLPAALKIAAAQMMLP--PE 401

  Fly   382 ALESVGEESSTQLAAIRWRYFNGKGEGVSHLLAGMQRLLSESLYELPYSRILELLNGTTS-YAYV 445
            .::.:.||            :.|..|....|.|..:.:|.:.::.:|..::......... |.|.
  Rat   402 CIDLIMEE------------YMGDTEDAETLQAQFKEMLGDFIFVIPALQVAHFQRSQAPVYFYE 454

  Fly   446 FDHSHSMDMRGRRNLFGGASHSSDLPLLLGPSLFQQIARRRFSGEEEQLCRKIRGAFANFIKNGN 510
            |.|..|. ::..|..:..|.|..|...:.| |.|..:. ...:.|||.|.|::...:|||.:.||
  Rat   455 FQHLLSF-IKQVRPFYPKADHGDDTVFVFG-SYFWGMT-FDLTEEEELLKRRVMKYWANFARTGN 516

  Fly   511 P 511
            |
  Rat   517 P 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	146/521 (28%)
Ces2j	XP_038953911.1	COesterase	50..555	CDD:395084	146/521 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910