Protein Alignment CG12869 and Ces1a

DIOPT Version :10

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_001177304.1
• Gene: Ces1a / 679817
• RGDID: 1583671
• Length: 563
• Species: Rattus norvegicus
• Alignment Length: 615
• Identity: 161/615 - (26%)
• Similarity: 255/615 - (41%)
• Gaps: 153/615 - (24%)

  Fly    35 QGDLIGLKVFPDGTRGAVYAFLGIPYAQAPINELRFAPAKPSSSFNRTLQATTMQPLCPQLANTI 99
            ||.::|..:..:|....|..|||:|:|:.|:..|||||.:|:.|::....||:..|:|.|:...
  Rat    30 QGKVLGKYISLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQPAESWSFVKNATSYPPMCSQITGV- 93

  Fly   100 YDESSDGSMPRSVSTD----------EDCLYLNIWTPESGMRYGKLPIVV------IVTGEEFAY 148
                  |.:...|.|:          ||||||||::|.......:||::|      :::|....:
  Rat    94 ------GPVLSEVFTNQLENVPLEYSEDCLYLNIYSPTDLTSKDRLPVMVWVHGGGLLSGGASTF 152

  Fly   149 DWPRNRINGLDLA-GEGIVVVSVQYRNNIYGWLSLGEQHRNVPGNYGLSDVQMALRWIRRNADAF 212
            |       ||.|: .|.:|||.:|||..|:|:||.|::|..  ||:|..|...||:|::.|...|
  Rat   153 D-------GLALSTHEKVVVVVIQYRLGIWGFLSTGDEHSR--GNWGHFDQVAALQWVQNNIVNF 208

  Fly   213 GGNPDHITLLGHGSGGAPLALVATLEDSSQVKQLVLMSPGPIMRALGQNHQKWIVETGQVLVQKL 277
            ||:|:.:||.|..:||            ..|..|||   .|:.:.|   ..:.|.|:|..|..
  Rat   209 GGDPNSVTLFGESAGG------------ESVSVLVL---SPLTKNL---FHRAISESGVALTP-- 253

  Fly   278 GCQFEEAQR-----------------RQLMGCLRRKSREDLLRA-----YESVYNHGNGSSQL-- 318
             |.|.|..|                 ..::.|||.|:.|:||..     :.::..||:.....
  Rat   254 -CLFRENTRLAAEQVAIATGCAATTSADIVRCLREKTEEELLATTLKMKFFALDLHGDPRESYPF 317

  Fly   319 ------GVILPEGLPLEQRL--RNKTLPPVLLGITSNE---------GAFLQDYWLDVAREGQVA 366
                  ||:||:. | |:.|  :|....|.::||...|         |..|.:..||......:.
  Rat   318 LTTVIDGVLLPKA-P-EEILSEKNFNTVPYIVGINKQEFGWFIPTMMGYPLSESKLDQKTATSLL 380

  Fly   367 LHKYINHTLLPNVMRALESVGEESSTQLAAIRWRYFNGKG--EGVSHLLAGMQRLLSESLYELP- 428
            ...|    .|.|:.:.|..|..|          :|..|..  :....|...|   :.:.|:.:|
  Rat   381 WKSY----PLTNISKELTPVATE----------KYLGGSDCPDKKKDLFLDM---MGDVLFAVPS 428

  Fly   429 -----YSRILELLNGTTSYAYVFDHSHSM--DMRGRRNLFGGASHSSDLPLLLGPSLFQQIARRR 486
                 |.|...    .|:|.|.|.:..|.  |||.:..:   |.|..::..:.|....::.|
  Rat   429 VIVARYHRDAR----ATTYVYEFKYHPSFVSDMRPKTVI---ADHGDEVYSVWGTPFLKEGA--- 483

  Fly   487 FSGEEEQLCRKIRGAFANFIKNGNPTPGRIYDGWLPYNKENPFVYSLGEQAKTPQTGSVDEAEVD 551
             |.||..|...:...:.||.:||||. |.....|..|:::..::          |.|:..: :..
  Rat   484 -SEEEINLSTMMMKFWGNFARNGNPN-GEGLPHWPEYDEKESYL----------QIGTTIQ-QAQ 535

  Fly   552 KLLRGE----TGAPGLDRSLSRSNRHDTYR 577
            ||...|    ||..|::  :..:...||.:
  Rat   536 KLKYKEVAFWTGLRGME--VEEATEEDTQK 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	151/573 (26%)
Ces1a	NP_001177304.1	COesterase	22..545	CDD:395084	156/593 (26%)