Protein Alignment CG12869 and Ces2b

DIOPT Version :10

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_001094469.1
• Gene: Ces2b / 679149
• RGDID: 1591847
• Length: 561
• Species: Rattus norvegicus
• Alignment Length: 546
• Identity: 149/546 - (27%)
• Similarity: 251/546 - (45%)
• Gaps: 107/546 - (19%)

  Fly    13 LLPILIHL----SPYIS-AQQTHIKLEQGDLIGLKVFPDGTRGAVYAFLGIPYAQAPINELRFAP 72
            ||.:|||:    ||..| .:.|||...:|.|..:|    .|:..|:.|||||:|:.|:..|||||
  Rat    17 LLLLLIHVQGQHSPESSPIRNTHIGQVRGKLDHVK----DTKAGVHTFLGIPFAKPPVGPLRFAP 77

  Fly    73 AKPSSSFNRTLQATTMQPLCPQLANTIYDESSDG------SMPRSVSTDEDCLYLNIWTPESGMR 131
            .:....::.....|:...:|.|..:.|   :::|      .:| .||..||||||||:.|.....
  Rat    78 PEAPEPWSGVRDGTSQPAMCLQNLDVI---NAEGLKEMKLKLP-PVSMSEDCLYLNIYAPAHAHE 138

  Fly   132 YGKLPIVV------IVTGEEFAYDWPRNRINGLDLAGEGIVVVSVQYRNNIYGWLSLGEQHRNVP 190
            ...||::|      ::||....||.....:|      |.:|||::|||..:.|:.|.|::|..
  Rat   139 GSNLPVMVWIHGGGLMTGMASMYDGSLLTVN------EDLVVVTIQYRLGVLGFFSTGDEHAR-- 195

  Fly   191 GNYGLSDVQMALRWIRRNADAFGGNPDHITLLGHGSGGAPLALVATLEDSSQVKQLVLMSPG--- 252
            ||:|..|...||||:::|...||||||.:|:.|..:||..::.......|..:....:|..|
  Rat   196 GNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGESAGGTCVSTHVVSPMSQGLFHGAIMESGVAL 260

  Fly   253 -PIMRALGQNHQKWIVETGQV---LVQKL-GCQFEEAQRRQLMGCLRRKSREDLLRAYESVYNHG 312
             |.:          |.:|.::   :|.|: ||:..:::  .|:.|||.||..::|...:.|
  Rat   261 LPYL----------IADTSEMFSTMVAKVSGCEAMDSE--ALVHCLRAKSEAEILAINKVV---- 309

  Fly   313 NGSSQL--GVILPEGLPL--EQRLRNKTLPPV--LLGITSNEGAFLQDYWL------------DV 359
                |:  .|:..|.||.  ::.|.::...||  ::|:.::|..     |.            ::
  Rat   310 ----QMVPAVVDGEFLPRHPKELLASEDFRPVPSIIGVNNDEYG-----WTIPLVMGTTQMIKEL 365

  Fly   360 AREG-QVALHKYINHTLLPNVMRALESVGEESSTQLAAIRWRYFNGKGEGVSHLLAGMQRLLSES 423
            :||. |..|.|.....:||  :...:.:.||            :.|..|....|.|....|:.:.
  Rat   366 SRENLQAILKKTTAQLMLP--LECSDLLMEE------------YMGDIEDPKTLQAQFTELMEDF 416

  Fly   424 LYELPYSRILELLNGTTSYA--YVFDHSHSMD-MRGRRNLFGGASHSSDLPLLLGPSLFQQIARR 485
            ::.:|   .|::.:...|:|  |.::..|.:. ::..|.....|.|..::|.:.|  .|....:.
  Rat   417 MFVIP---ALQVAHFQCSHAPVYFYEFQHQITFLKDIRPPHVKADHGDEIPFVFG--YFFWDMKT 476

  Fly   486 RFSGEEEQLCRKIRGAFANFIKNGNP 511
            .|:.||:.|.|::...:|||.::|||
  Rat   477 DFTEEEKLLSRRMMKYWANFARHGNP 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	141/527 (27%)
Ces2b	NP_001094469.1	COesterase	32..540	CDD:395084	142/531 (27%)