Protein Alignment CG12869 and ces2a

DIOPT Version :9

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_001070720.1
• Gene: ces2a / 566132
• ZFINID: ZDB-GENE-061013-99
• Length: 555
• Species: Danio rerio
• Alignment Length: 610
• Identity: 162/610 - (26%)
• Similarity: 251/610 - (41%)
• Gaps: 144/610 - (23%)

  Fly    13 LLPILIHLSPYISAQQTH-----IKLEQGDLIGLKVFPDGTRGAVYAFLGIPYAQAPINELRFAP 72
            ||.:.:.|:|..||....     ..|:.|.:.|..|...|:...|..:||||:||.|:...|.|.
Zfish     6 LLCLCLTLAPVWSAPVQEDSGPVAVLKHGSVRGQYVKAKGSPAVVEQYLGIPFAQPPVGPHRLAA 70

  Fly    73 AKPSSSFNRTLQATTMQPLC-------PQLANTIYDESSDGSMPRSVSTDEDCLYLNIWTPESGM 130
            .:|...:.....||....:|       |.:|..|..|.:      ::...|||||||::||....
Zfish    71 PQPVQGWEGIRNATEHPLMCLQNPDILPAIAKAIDLEVT------AIGVSEDCLYLNVYTPSQRA 129

  Fly   131 RYGKLPIVVIVTGEEFA------------YDWPRNRINGLDLAG-EGIVVVSVQYRNNIYGWLSL 182
            ...|||:::.:.|...|            ||       |..||. |.:|||.:|||..|.|:.|.
Zfish   130 ESEKLPVMIWIHGGGLAMGGACMFKELCLYD-------GTPLAAYEKVVVVVIQYRLGILGYFST 187

  Fly   183 GEQHRNVPGNYGLSDVQMALRWIRRNADAFGGNPDHITLLGHGSGGAPLALVATLEDSSQVKQLV 247
            |:||  ..||:|..|...||:|:::|.:||||:|..:|:.|..:||...:|:.          |.
Zfish   188 GDQH--AKGNWGFLDQIAALQWVQQNIEAFGGDPQSVTIAGESAGGISASLLT----------LS 240

  Fly   248 LMSPGPIMRALGQNH----QKWIVET----GQVLVQKLGCQFEEAQRRQLMGCLRRKSREDLLRA 304
            .|:.|...||:.|:.    :.:.|:.    .||:.....|.|..::  .|:.|:|..:.|.:::|
Zfish   241 PMTKGLFQRAIFQSGVATVKGYFVKDPSTHAQVIANITECDFSSSE--VLVKCIREMTEEQIIKA 303

  Fly   305 YESVYNHGNGSSQLGVILP---------EGLPLEQRLRNKTLP--PVLLGITSNEGAFLQDYWLD 358
                       :|...|.|         :..| |:.|::|...  |:|:|.|::|..     |
Zfish   304 -----------AQKKGIFPGAAVDGEFIKAQP-EEILKSKDFQKVPILIGTTNHEFG-----W-- 349

  Fly   359 VAREGQVALHKYINHTLLPNVMRALESVGEESSTQLAAIRWRYFNGKG-EGVSHLLA-------- 414
                            :||.:....|.| :...|:.|..|....|..| .|.:.::|
Zfish   350 ----------------MLPQIFLPKEWV-KGMDTKAAKDRLGLLNADGASGANGIIADEYFKNAK 397

  Fly   415 -------GMQRLLSESLYELP------YSRILELLNGTTSYAYVFDHSHSMDMRGRRNLFGGASH 466
                   ....||.:....:|      |.|..    |...|.|.|.|..|...:.|.: |..|.|
Zfish   398 TPEEIRDAFTELLGDIFMVIPSITVASYHREA----GVPVYMYEFQHGPSTANKFRPS-FVKADH 457

  Fly   467 SSDLPLLLGPSLFQQIAR--RRFSGEEEQLCRKIRGAFANFIKNGNPTPGRIYDGWLPYNKENPF 529
            :.|:..:.|...:....:  ...:.||.||||.:....||||:.|:|.|..:  .|..|::.|.:
Zfish   458 ADDVGFVFGACFWDVHVKGLGTLTEEENQLCRTVMKYRANFIRTGSPNPAPV--PWPVYDQSNKY 520

  Fly   530 VYSLGEQAKTPQTGSVDEAEVDKLL 554
            : :||.|    ||...| .:.||||
Zfish   521 L-NLGLQ----QTEGQD-LKKDKLL 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	149/581 (26%)
ces2a	NP_001070720.1	COesterase	21..541	CDD:278561	156/595 (26%)
		Aes	<122..346	CDD:223730	70/256 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D233524at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010