Protein Alignment CG12869 and cel.2

DIOPT Version :10

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_001020344.2
• Gene: cel.2 / 565117
• ZFINID: ZDB-GENE-061110-10
• Length: 551
• Species: Danio rerio
• Alignment Length: 613
• Identity: 144/613 - (23%)
• Similarity: 240/613 - (39%)
• Gaps: 148/613 - (24%)

  Fly    10 ILRLLPILIHLSPYISAQQ---THIKLEQGDLIGLKVFPDGTRGAVYAFLGIPYAQAPINELRFA 71
            ::.:|.:.|..:.::...|   ....|.:|.::..|....|....:..|.|||:|..|   .|..
Zfish     1 MMMMLGVFISAALFLGTAQGASLGAVLTEGGMVQGKSHSVGLLRYMDVFKGIPFAAPP---GRLQ 62

  Fly    72 PAKPSSSFNRTLQATTMQPLCPQLANTIYDESSDGSMPRSVSTDEDCLYLNIWTPESGMRYGKLP 136
            ...|...:...|:||.....|.||  .:....:.||        |||||||||.|:.......||
Zfish    63 KPVPHPGWEGVLKATEYSKRCIQL--NLLQTDTMGS--------EDCLYLNIWVPQGKTVSYNLP 117

  Fly   137 IVVIVTG--------------EEFAYDWPRNRINGLDLAGEG-IVVVSVQYRNNIYGWLSLGEQH 186
            ::|.:.|              :.:.||       |.::|..| ::||:..||....|:||.|:
Zfish   118 VMVFIYGGGFLLGGGQGANFLDNYLYD-------GEEIADRGNVIVVTFNYRVGSMGFLSTGD-- 173

  Fly   187 RNVPGNYGLSDVQMALRWIRRNADAFGGNPDHITLLGHGSGGAPLALVATLEDSSQVKQLVLMSP 251
            .:.||||||.|...|:.|:.||..|||||||:||:.|..:|...:             ...::||
Zfish   174 ADAPGNYGLWDQHAAISWVHRNIKAFGGNPDNITIFGESAGSTSV-------------NFQIISP 225

  Fly   252 ---GPIMRALGQ------------NHQKWIVETGQVLVQKLGCQFEEAQRRQLMGCLRRKSREDL 301
               |.|.||:.|            |.:|:..|    :.:|:||..:..    ::.||||...:.:
Zfish   226 KNKGLIRRAISQSGVALCPWAINRNPRKFAEE----IAKKVGCPTDSG----MVACLRRTDPKAV 282

  Fly   302 LRAYESVYNHGNGSSQLGVILPEGLPLEQRLRNKTLPPVLLGITSNEGAFLQD----YWLDVARE 362
            ..|         |..:|.....|.:     :.|..|.||:      :|.|:.|    .:.:.|..
Zfish   283 TLA---------GKVRLATSATEPI-----VHNLYLSPVI------DGDFIPDEPDTLFGNAADI 327

  Fly   363 GQVA----LHKYINHTL-LPNVMRALESVGEESSTQLA-------------------AIRWRYFN 403
            ..:|    :..:|..|| :|::..||.:..||....||                   .:.|....
Zfish   328 DYIAGVNDMDGHIFATLDIPSINNALATTTEEEVQALATALSKDRGQDAGIATFQEYTVNWGSKP 392

  Fly   404 GKGEGVSHLLAGMQRLLSESLYELPYSRILEL----LNGTTSYAYVFDHSHSMDMRGRRNLFGGA 464
            .| |.:...:..|:   ::.::.:|....|.|    .....:|:|:|..|..:.:   ..|:.||
Zfish   393 NK-EDIKKTVVEME---TDYIFLVPTQTALYLHSDNAKSARTYSYLFSESSRIPI---FPLWMGA 450

  Fly   465 SHSSDLPLLLGPSLFQQIARRRFSGEEEQLCRKIRGAFANFIKNGNPTPG--RIYDGWLPYNKEN 527
            .|:.:|..:.|......:.   :......:.:.:...:.||.:.|||..|  ::...|..::  |
Zfish   451 DHADELQYVFGKPFTTPLG---YFPRHRDVSKYMIAYWTNFAQTGNPNTGESKVPVTWPEFS--N 510

  Fly   528 PFVYSLGEQAKTPQTGSVDEAEVDKLLR 555
            |     |.| .......::...|.|:||
Zfish   511 P-----GHQ-YLDINNKINTNSVKKMLR 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	138/580 (24%)
cel.2	NP_001020344.2	COesterase	26..539	CDD:395084	141/588 (24%)