Protein Alignment CG12869 and nlgn3a

DIOPT Version :10

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: XP_005157256.1
• Gene: nlgn3a / 562702
• ZFINID: ZDB-GENE-071219-1
• Length: 878
• Species: Danio rerio
• Alignment Length: 690
• Identity: 151/690 - (21%)
• Similarity: 250/690 - (36%)
• Gaps: 235/690 - (34%)

  Fly     1 MWNALRIQQILRLLPILIHLSPYISAQQTHIKL-----------------------EQGDLIGLK 42
            ||.|:|.::      :|:|.....|.:..:|.|                       :.|.|.|.:
Zfish    24 MWLAMRKKR------LLLHHQDCCSRRACNISLWILVFCWCMMLVRGQGYYPTVNTQYGKLRGAR 82

  Fly    43 V-FPDGTRGAVYAFLGIPYAQAPINELRFAPAKPSSSFNRTLQATTMQPLCPQLANTIYDESSDG 106
            | ......|.|..:||:|||..|:.|.||.|.:|.||::....||...|:|||   .|::...:.
Zfish    83 VPLHSEILGPVDQYLGVPYATPPVGEKRFLPPEPPSSWSGIKNATHFAPVCPQ---NIHNAVPEI 144

  Fly   107 SMP-------RSVST-----DEDCLYLNIWTPESGMR---------------------------- 131
            .||       ..|:|     :||||||||:.|...::
Zfish   145 MMPIWFTFNLDIVATSIQDQNEDCLYLNIYVPTEDVKRISKECTRKPNKKICRKGGTHSKKQGED 209

  Fly   132 --------------YGKLPIVVIVTGEEFAYDWPRNRINGLDLAGEG-IVVVSVQYRNNIYGWLS 181
                          .|..|::|.:.|..: .:...|.|:|..||..| ::|:::.:|..:.|:||
Zfish   210 LSDNDGDEDEDIRDTGAKPVMVYIHGGSY-MEGTGNMIDGSVLASYGNVIVITLNFRVGVLGFLS 273

  Fly   182 LGEQHRNVPGNYGLSDVQMALRWIRRNADAFGGNPDHITLLGHGSGGAPLALVATLEDSSQVKQL 246
            .|:|  ...|||||.|...|||||..|...|||:.:.||:.|.|.|.:.::|:.....|..:...
Zfish   274 TGDQ--AAKGNYGLLDQIQALRWISENIGYFGGDSNRITVFGSGIGASCVSLLTLSHHSEGLFHR 336

  Fly   247 VLMSPGPIMRALGQNHQKWIVETGQVLVQKLGCQFEEAQRRQLMGCLRRKSREDLLR--AYESVY 309
            .::..|..:.:...|:|.  |:..::|.:|:||...:.  ..::.|||:||..:|:.  ...:.|
Zfish   337 AIIQSGSALSSWAVNYQP--VKYTRLLAEKVGCNVLDT--LDMVDCLRKKSARELVEQDIQPARY 397

  Fly   310 NHGNGSSQLGVILPEG--LPLEQ-RLRNKTLPPVLLGITSNEG---------------------- 349
            :...|....|.::|:.  :.:|| ...|.   .::||:...||
Zfish   398 HVAFGPVIDGDVIPDDPEILMEQGEFLNY---DIMLGVNQGEGLRFVENVVDSEDGVSGNDFDFS 459

  Fly   350 ----------------------AFLQDYWLD-----VAREGQVAL---HKYINHTLLPNVMRALE 384
                                  .|:...|.|     ..|:..|||   |:::
Zfish   460 VSDFVDSLYGYPEGKDTLRETIKFMYTDWADRDNPETRRKTLVALFTDHQWV------------- 511

  Fly   385 SVGEESSTQLAAIRWRYFNGKGEGVSHLLAGMQRLLSESLYELPYSRILELLNGTTSYAYVFDHS 449
                |.|...|.:..||                                    |:.:|.|.|.|
Zfish   512 ----EPSVVTADLHARY------------------------------------GSPTYFYAFYH- 535

  Fly   450 HSMDMRGRRNLFGGASHSSDLPL-----LLGPS-LFQQIARRRFSGEEEQLCRKIRGAFANFIKN 508
            |...:  .:..:..|:|..::|.     ::||: ||.    ..||..:..|...:...:.||.|.
Zfish   536 HCQSL--MKPAWSDAAHGDEVPYVFGIPMIGPTDLFP----CNFSKNDIMLSAVVMTYWTNFAKT 594

  Fly   509 GNP------------TPGRIYD--GWLPYNKENPFVYSLG 534
            |:|            |....::  .|..||.::.....:|
Zfish   595 GDPNKPVPQDTKFIHTKANRFEEVAWSKYNPQDQLYLHIG 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	144/664 (22%)
nlgn3a	XP_005157256.1	COesterase	69..651	CDD:395084	142/639 (22%)