Protein Alignment CG12869 and nlgn4xa

DIOPT Version :10

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: XP_021330915.1
• Gene: nlgn4xa / 561122
• ZFINID: ZDB-GENE-100309-2
• Length: 844
• Species: Danio rerio
• Alignment Length: 598
• Identity: 153/598 - (25%)
• Similarity: 258/598 - (43%)
• Gaps: 104/598 - (17%)

  Fly    11 LRLLPILIHLSPYIS---AQQTH--IKLEQGDLIGLKV-FPDGTRGAVYAFLGIPYAQAPINELR 69
            |||...::..:.:::   ||| |  :....|.|.|||. .|:...|.|..:||||||..|..|.|
Zfish    21 LRLFTWIVLAAAWLAITWAQQ-HPIVTTNYGKLRGLKTPLPNEILGPVEQYLGIPYALPPTGERR 84

  Fly    70 FAPAKPSSSFNRTLQATTMQPLCPQ------LANTI----YDESSDGSMPRSVSTDEDCLYLNIW 124
            |.|.:|..|:.....||...|:|||      |.|.:    :..:.|..:.......||||||||:
Zfish    85 FQPPEPPMSWPGIRNATQFAPVCPQFLEDRFLLNDMLPVWFTANLDTVVTYVQDQSEDCLYLNIY 149

  Fly   125 TP-------------------------ESGMRYGKLPIVVIVTGEEFAYDWPRNRINGLDLAGEG 164
            .|                         |:|:|    |::|.:.|..: .:...|.|:|..||..|
Zfish   150 VPTEDVGANKGDDFTNNEGGENKDIHDENGLR----PVMVYIHGGSY-MEGTGNMIDGSILASYG 209

  Fly   165 -IVVVSVQYRNNIYGWLSLGEQHRNVPGNYGLSDVQMALRWIRRNADAFGGNPDHITLLGHGSGG 228
             ::||::.||..:.|:||.|:|  ...|||||.|...|||||:.|..||.|:|..:|:.|.|:|.
Zfish   210 NVIVVTLNYRLGVLGFLSTGDQ--AAKGNYGLLDQIQALRWIKENIQAFKGDPKRVTIFGSGAGA 272

  Fly   229 APLALVATLEDSSQVKQLVLMSPGPIMRALGQNHQKWIVETGQVLVQKLGCQFEEAQRRQLMGCL 293
            :.::|:.....|..:.|..::..|..:.:...|:|.  .:..::|.:|:||...::  ..|:.||
Zfish   273 SCVSLLTLSHYSEDLFQKAIIQSGTALSSWAVNYQP--AKYTRILAEKVGCNMLDS--IDLVECL 333

  Fly   294 RRKSREDLLRAY--ESVYNHGNGSSQLGVILPEG--LPLEQ-RLRNKTLPPVLLGITSNEGAFLQ 353
            :.|:.::|:..|  ::.|:...|....|.::|:.  :.:|| ...|.   .::||:...||....
Zfish   334 QNKNYKELIEQYITQAKYHIAFGPVIDGDVIPDDPQILMEQGEFLNY---DIMLGVNQGEGFKFV 395

  Fly   354 DYWLD-----VAREGQVALHKYINHTLLPNVMRALESVGEESSTQLAAIRWRYFN-GKGEGVSHL 412
            |..:|     .|.:...|:..:::|         |....|...|....|::.|.: ...|.....
Zfish   396 DGIVDSEDGVSANDFDFAVSDFVDH---------LYGYPEGKDTLRETIKFMYTDWADKENPETR 451

  Fly   413 LAGMQRLLSESLYELPYSRILEL--LNGTTSYAYVFDHSHSMDMRGRRNLFGGASHSSDLPL--- 472
            ...:..|.::..:..|.....:|  ..|:.:|.|.|.|....:|:..   :..::|..::|.
Zfish   452 RKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPS---WSDSAHGDEVPYVFG 513

  Fly   473 --LLGPSLFQQIARRRFSGEEEQLCRKIRGAFANFIKNGNPT-------------PGRIYD-GWL 521
              :|||:   .:....||..:..|...:...:.||.|.|:|.             |.|..: .|.
Zfish   514 IPMLGPT---DLFNCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWS 575

  Fly   522 PYNKENPFVYSLG 534
            .||.::.....:|
Zfish   576 KYNPKDQLYLHIG 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	149/579 (26%)
nlgn4xa	XP_021330915.1	COesterase	43..605	CDD:395084	146/575 (25%)