Protein Alignment CG12869 and LOC4576394

DIOPT Version :10

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: XP_001237725.3
• Gene: LOC4576394 / 4576394
• VectorBaseID: AGAMI1_012689
• Length: 580
• Species: Anopheles gambiae
• Alignment Length: 664
• Identity: 162/664 - (24%)
• Similarity: 259/664 - (39%)
• Gaps: 168/664 - (25%)

  Fly     5 LRIQQILRLLPILIHLSPYISAQQTHIKL--EQGDLIGLKVFPDGTRGAVY-AFLGIPYAQAPIN 66
            :|...:::||.|...:...:..|..|.::  :.|.|:|..:  ..|:...: ||:|||||:.|:.
Mosquito     1 MRYSVVMKLLVIFGAVLVTVGGQLKHPRVCTDDGCLLGTSM--TDTKNLRFDAFVGIPYAKPPVG 63

  Fly    67 ELRFAPAKPSSSFNRTLQATTMQPLCPQLANTIYDESSDGSMPRSVSTDEDCLYLNIWTPESGMR 131
            :|||....|...:.....||..:|.|.|.:..:..:...|        ||:|||||::.|:....
Mosquito    64 KLRFKKPIPIEPWTEDYNATESKPACLQKSFLLPGQPIVG--------DENCLYLNVYRPKGNGS 120

  Fly   132 YGKLPIVVIVTGEEFAYDWPRNRINGLD--LAGEGIVVVSVQYRNNIYGWLSLGEQHRNVPGNYG 194
            ...||::|.:.|..:.:.....::.|.:  ||.:.:::|::|||..:.|:||.|:.|  ..||||
Mosquito   121 AVPLPVMVFIHGGGYFFGSADPQLYGPERILATKQVILVTLQYRLGVLGFLSTGDAH--ATGNYG 183

  Fly   195 LSDVQMALRWIRRNADAFGGNPDHITLLGHGSGGAPLALVATLEDSSQVKQLVLMSP---GPIMR 256
            :.|..:||||:.|:..||||:|..:||.|..:|||.:             ||.:|||   |...|
Mosquito   184 MLDQVLALRWVNRHIGAFGGDPHSVTLFGESAGGASV-------------QLHMMSPLSVGLFQR 235

  Fly   257 ALGQNHQKWIVETGQVL-VQKLGCQFEEAQRR---QLMGCLRRKSREDLLRAYESV--------- 308
            |        |:.:|..| |..|..|...|..|   :|:|.    |..|.|...|.|
Mosquito   236 A--------IIMSGSALAVWSLPIQDPLALARKQAKLVGV----SEADELTTAELVDVLQYLDAK 288

  Fly   309 ------------YNHG--------NGSSQLGVILPEGLPLEQRLRNKTLP--------------- 338
                        :.|.        .|:|         :|.|:|.    ||
Mosquito   289 VLTASMPHLRTWFEHPIVMYRPTVQGAS---------VPSEERF----LPDDPRKLWAEGRYVDI 340

  Fly   339 PVLLGITSNEGAFLQDYWLDVAREGQVALHKYINHTLLPNVMRALESV--------GEESSTQLA 395
            |:::|...||||.             |:|....|.|:|......|:.:        |.:|  .|.
Mosquito   341 PIMIGTVPNEGAV-------------VSLAIVHNETILEQFNENLKELLVPVLAINGTDS--VLE 390

  Fly   396 AIRWRYF----NG---KGEGVSHLLAGMQRLLSESLYELP-YSRILELLNG-------TTSYAYV 445
            .::.|||    |.   |.:....    ..:::|::..:.| ...:|:..|.       ||.|::.
Mosquito   391 QLKGRYFPKATNNRWIKEDNADQ----FTKMMSDAFIKYPTIKTLLQYANSNQTSCRDTTLYSFE 451

  Fly   446 FDHSHSM-DMRGRRNLFGGASHSSDLPLLLGP-SLFQQIARRRFSGEEEQLCRKIRGAFANFIKN 508
            |:..||. .:..:.|...|..|..:|..|... .||.....   ...|.::|........||..|
Mosquito   452 FEGRHSFSSLYIQSNASHGVCHQDELLYLYRMIDLFPDFPP---DSPETEMCNAWTEFLVNFASN 513

  Fly   509 -GNPTPGRIYDGWLPYNKENPFVYSLGEQAKTPQTGSVDEAEVDKLLRGETGAPGLDRSLSRSNR 572
             ..|...|..|.      .|....:.|....:|::.|...|.:      .:...|||..:.|  .
Mosquito   514 ETRPDSSRSCDA------NNIQTVTFGNAKSSPESTSAASAVL------VSSGNGLDAEMER--M 564

  Fly   573 HDTYRAAPSNSYTA 586
            |:.:.....:||.|
Mosquito   565 HEFWSTVYGSSYIA 578

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	147/595 (25%)
LOC4576394	XP_001237725.3	None