Protein Alignment CG12869 and Ces2h

DIOPT Version :10

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_001258974.1
• Gene: Ces2h / 436059
• MGIID: 3648740
• Length: 558
• Species: Mus musculus
• Alignment Length: 602
• Identity: 151/602 - (25%)
• Similarity: 254/602 - (42%)
• Gaps: 138/602 - (22%)

  Fly     5 LRIQQI-LRL------LPILIHLSPYISA---QQTHIKLEQGDLIGLKVFPDGTRGAVYAFLGIP 59
            :|::|| .||      |.:|:.:....|.   :.||.....|.||.:|....|    |::|||||
Mouse     1 MRLEQIHARLTTATCGLLLLLRVQGQDSTSPIRTTHTGQILGSLIHMKDLDVG----VHSFLGIP 61

  Fly    60 YAQAPINELRFAPAKPSSSFNRTLQATTMQPLCPQ------------LANTIYDESSDGSMPRSV 112
            :|:.|:..|||||.:|...:......|:...:|.|            |..|:      ...|.|
Mouse    62 FAKPPVGPLRFAPPEPPEPWGGVRDGTSHPAMCLQDITAMNMQAFKLLKLTL------PPFPMS- 119

  Fly   113 STDEDCLYLNIWTPESGMRYGKLPIVV------IVTGEEFAYDWPRNRINGLDLAG-EGIVVVSV 170
               ||||||||:.|:.......||::|      :|.|....||       |..||. |.:|||::
Mouse   120 ---EDCLYLNIYAPDHAHEGSNLPVMVWIHGGSLVIGMASMYD-------GSMLAAMENVVVVTI 174

  Fly   171 QYRNNIYGWLSLGEQHRNVPGNYGLSDVQMALRWIRRNADAFGGNPDHITLLGHGSGGAPLALVA 235
            |||..:.|:.|.|::...  ||:|..|...||||:::|...||||||.:|:.|..:||
Mouse   175 QYRLGVLGFFSTGDERAR--GNWGYLDQVAALRWLQQNIAYFGGNPDRVTIFGTSAGG------- 230

  Fly   236 TLEDSSQVKQLVL--MSPGPIMRALGQNHQKWIVETGQVLVQKL----------------GCQFE 282
                 :.|..||:  ||.|....|        |:|:|..|:..|                ||  |
Mouse   231 -----TSVSSLVVSPMSQGLFRGA--------IMESGVALISSLISVSSDVVYQTVANLSGC--E 280

  Fly   283 EAQRRQLMGCLRRKSREDLL---RAYESVYNHGNGSSQLGVILPEGLPLEQRLRNKTLP-PVLLG 343
            :.....|:.|||.||.|:::   :|::.:....:     |:.||.. |.|........| |.::|
Mouse   281 QVDSEALVNCLRGKSEEEIMAINKAFKIIPGIVD-----GIFLPRH-PQELMASADFHPVPSIIG 339

  Fly   344 ITSNEGAFLQDYWLDVAREGQVALHKYINHTLLPNVMRALESVGEESSTQL------AAIRWRYF 402
            :.::|..     |:..:....:...|.::..:       ::::.:..:||:      :.:....:
Mouse   340 VNNDEYG-----WIIPSSMSMIDSKKGMDRQM-------VQAILQRRATQMMWPPEVSDLLMEEY 392

  Fly   403 NGKGEGVSHLLAGMQRLLSESLYELPYSRILELLNGTTSYA----YVFDHSHSMDMRGRRNLFGG 463
            .|..|....|....:.::.:..:.:|   .|::.....|:|    |.|.|..|. .:..:.....
Mouse   393 MGDNEDPQFLQVQFKEMMKDFTFVIP---ALQVAQFQRSHAPVFFYEFQHRPSF-FKDSKPSHVK 453

  Fly   464 ASHSSDLPLLLGPSLFQQIARRRFSGEEEQLCRKIRGAFANFIKNGNP-TPGRIYDGWLPYNKEN 527
            |.|..::..:.  ..|....:..|:.|||.|.|::...:|||.:..|| :.|..|  |..::::.
Mouse   454 ADHGDEILFIF--RSFWGGTQVDFTEEEELLSRRMMKYWANFARQRNPNSEGLPY--WPMFDQDE 514

  Fly   528 PFVY-----SLGEQAKT 539
            .::.     ::|...||
Mouse   515 QYLQLDTQPAVGRALKT 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	143/570 (25%)
Ces2h	NP_001258974.1	COesterase	30..537	CDD:395084	143/573 (25%)