Protein Alignment CG12869 and Ace

DIOPT Version :10

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_476953.1
• Gene: Ace / 41625
• FlyBaseID: FBgn0000024
• Length: 649
• Species: Drosophila melanogaster
• Alignment Length: 722
• Identity: 161/722 - (22%)
• Similarity: 275/722 - (38%)
• Gaps: 177/722 - (24%)

  Fly    14 LPILIHLSPYISA-----QQTHIKLEQGDLIGLKVFPDGTRGAVYAFLGIPYAQAPINELRFAPA 73
            ||:::.||.::|.     .:..::...|.:.|..|...|..  |:.:.|||||:.|:.:|||...
  Fly    23 LPLVLVLSLHLSGVCGVIDRLVVQTSSGPVRGRSVTVQGRE--VHVYTGIPYAKPPVEDLRFRKP 85

  Fly    74 KPSSSFNRTLQATTMQPLCPQLANTIYDE-SSDGSMPRSVSTDEDCLYLNIWTP-ESGMRYGK-- 134
            .|:..::..|.||.:...|.|.....:.. |.:.....:.:..|||||:|:|.| ::.:|:|:
  Fly    86 VPAEPWHGVLDATRLSATCVQERYEYFPGFSGEEIWNPNTNVSEDCLYINVWAPAKARLRHGRGA 150

  Fly   135 ----------------------------LPIVVIVTGEEFAYDWPRNRINGLDL--AGEGIVVVS 169
                                        |||::.:.|..|........|...|:  |...::|.|
  Fly   151 NGGEHPNGKQADTDHLIHNGNPQNTTNGLPILIWIYGGGFMTGSATLDIYNADIMAAVGNVIVAS 215

  Fly   170 VQYRNNIYGWLSL-----GEQHRNVPGNYGLSDVQMALRWIRRNADAFGGNPDHITLLGHGSGGA 229
            .|||...:|:|.|     .|.....|||.||.|..:|:||::.||.||||||:.:||.|..:|
  Fly   216 FQYRVGAFGFLHLAPEMPSEFAEEAPGNVGLWDQALAIRWLKDNAHAFGGNPEWMTLFGESAG-- 278

  Fly   230 PLALVATLEDSSQVKQLVLMSP---GPIMRAL---GQNHQKW-------IVETGQVLVQKLGCQF 281
                      ||.| ...||||   |.:.|.:   |..:..|       .||.|:.|:....|..
  Fly   279 ----------SSSV-NAQLMSPVTRGLVKRGMMQSGTMNAPWSHMTSEKAVEIGKALINDCNCNA 332

  Fly   282 E--EAQRRQLMGCLRRKSREDL----LRAYESVYNHGNGSSQLGVILPEGLPLEQRLRNKTLPPV 340
            .  :.....:|.|:|....:.:    ..:|..:.:..:..:..|..||.......:..:.....:
  Fly   333 SMLKTNPAHVMSCMRSVDAKTISVQQWNSYSGILSFPSAPTIDGAFLPADPMTLMKTADLKDYDI 397

  Fly   341 LLGITSNEGAF--LQDYWLDVAREGQVAL--HKYINHTLLPNVMRALESVGEESSTQLAAIRWRY 401
            |:|...:||.:  |.|:.....::...||  .||:.  ::.|:.      |:.:..:..||.::|
  Fly   398 LMGNVRDEGTYFLLYDFIDYFDKDDATALPRDKYLE--IMNNIF------GKATQAEREAIIFQY 454

  Fly   402 FNGKGEGVSHLLAGMQRLLSESLYELPYSRILELL--NGTTSYAYVFDHSHSMDMRGRRNLFGGA 464
            .:.:|.........:.|.:.:..:..|.:...:.|  .|.:.:.|.|.|..|..:.|.   :.|.
  Fly   455 TSWEGNPGYQNQQQIGRAVGDHFFTCPTNEYAQALAERGASVHYYYFTHRTSTSLWGE---WMGV 516

  Fly   465 SHSSDLPLLLGPSLFQQIARRRFSGEEEQLCRKIRGAFANFIKNGNPTPGRIYDG--WLPYNKEN 527
            .|..::....|..|...:   ::...|.:|.:::..|...|.|.|||.    .||  |..::||:
  Fly   517 LHGDEIEYFFGQPLNNSL---QYRPVERELGKRMLSAVIEFAKTGNPA----QDGEEWPNFSKED 574

  Fly   528 PFVYSLGEQAKTPQTGSVDEAEVDKLLRGETGAPGLDRSLSRSNRHDTYRAAPSNSYTASNQLDS 592
            |..|..          |.|: :::||.||...|                |.:
  Fly   575 PVYYIF----------STDD-KIEKLARGPLAA----------------RCS------------- 599

  Fly   593 GYSNHLQMVYGFWQVLMPLERE-----EDLRGGGALGQRVRLLEASADAARYRQGFYAMLGLVCL 652
                       ||...:|..|.     :...|..::..|::|                 ||:..|
  Fly   600 -----------FWNDYLPKVRSWAGTCDGDSGSASISPRLQL-----------------LGIAAL 636

  Fly   653 LLACLCL 659
            :..|..|
  Fly   637 IYICAAL 643

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	136/579 (23%)
Ace	NP_476953.1	COesterase	43..601	CDD:395084	144/641 (22%)