Protein Alignment CG12869 and Nlg1

DIOPT Version :9

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_001246966.1
• Gene: Nlg1 / 40913
• FlyBaseID: FBgn0051146
• Length: 1354
• Species: Drosophila melanogaster
• Alignment Length: 719
• Identity: 170/719 - (23%)
• Similarity: 275/719 - (38%)
• Gaps: 182/719 - (25%)

  Fly    19 HLSPYISAQQTHIKLEQGDLIGLKVFPDGTRG--AVYAFLGIPYAQAPINELRFAPAKPSSSFNR 81
            |:.|........|:::||.|:|:......|.|  .|..|||:|||:||....||.|......:..
  Fly   146 HVVPDKLQYTQEIQVKQGRLMGITRRFQVTSGLRQVDQFLGLPYAEAPTGNRRFMPPGAPLPWQG 210

  Fly    82 TLQATTMQPLCPQLANTIYDESSDGS--------------MPRSVSTDEDCLYLNIWTP--ESGM 130
            ...|..:.|:|||   .:.|.|..||              :|...:..|||||||::.|  |...
  Fly   211 LKIARHLPPVCPQ---KLPDLSPHGSENMSRARHKHLSRLLPYLRTESEDCLYLNLYVPHEEPQS 272

  Fly   131 RYGKLPIVVIVTGEEFAYDW-PRNRINGLDLAGEG-IVVVSVQYRNNIYGWLSLGEQHRNVPGNY 193
            ...:..::|.:.||.|  :| ..|..:|..|:..| ::||:|.||..:.|:|.......|: .||
  Fly   273 TPKQYAVLVYLHGESF--EWNSGNPYDGSVLSSYGEVIVVTVNYRLGVLGFLRPSIDAHNI-ANY 334

  Fly   194 GLSDVQMALRWIRRNADAFGGNPDHITLLGHGSGGA--------PLALVATLEDSSQVKQLVLMS 250
            .|.|...||.||:.|.:||||:...:||:||.:|.|        |:|       |....:.:|||
  Fly   335 ALLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACVNYLMVSPVA-------SGLFHRAILMS 392

  Fly   251 PGPIMRALGQNHQKWIVETGQVLVQKLGCQFEEAQRRQ----LMGCLRRKSREDLLRAYESVYNH 311
             |..|.....::|.  ::....:...|.|...|....:    |:.|||.:..:|:|....::...
  Fly   393 -GSAMSDWAASNQS--LQLTMQIAHALECPLNEHVEAEDDDVLLDCLRHRRYQDILHIPTALTQF 454

  Fly   312 GNGSSQLGVILPEG--LP------LEQRLRNKTLPPVLLGITSNEGAFLQDYWLDVAREGQVALH 368
               |:.||.|: :|  :|      :.....:.:...:|.|||.:|     .|....|...:..|.
  Fly   455 ---STSLGPIV-DGHVIPNQPYKVMGHYTEHFSRYDLLFGITESE-----SYHTLAALALEEGLR 510

  Fly   369 KYINHTLLPNVMRALESVGEESSTQLAAIRWRY---FNG--KGEGVSH------LLAGMQ---RL 419
            :.....||...|::...:..:.:  |||...:|   :|.  |...:.|      :|:..:   .|
  Fly   511 ENERDNLLRFYMQSRFDIRPDLA--LAATLKKYQDMYNNPIKATNLEHRDVVLDILSDARVVGPL 573

  Fly   420 LSESLYELPYSRILELLNGTTSYAYVFDHSHSMDMRGRRNLFGGASHS---SDLPLLLGPSLFQ- 480
            |...::....:|        .:|.|||.|:.:      ...|....||   .:|..:.|..|..
  Fly   574 LQTGMFHADVNR--------RNYMYVFGHNSA------TGPFAHLPHSIMGEELAFIFGAPLAAA 624

  Fly   481 -QIARRRFSGEEEQLCRKIRGAFANFIKNGN---------------------------------- 510
             ......::.:|:.|...:...:.||:|.||
  Fly   625 GPFPSGNYTVQEKLLSEAVMAYWTNFVKTGNPKAPWKGIFINSHALEWDRYDLDWPEFNRRAQAY 689

  Fly   511 ------PTPG----RIYDGWLPYNKENP----FVYSLGEQAKTP---------------QTGSVD 546
                  ||.|    :||..:  :|||.|    .:.::.||.:.|               ..|:.|
  Fly   690 LNIGIPPTVGYKYRQIYMNF--WNKELPDELNQIAAIQEQLQKPGQEVITGHMSKYGPRDHGAED 752

  Fly   547 EAEVDKLLRGETGAPGLDRS--LSRSNRHDTYRAAPSNSY--------------TASNQLDSGYS 595
            .....|||..|....|..:|  .:.:...:.|.|.|:..:              |::|.|:|| .
  Fly   753 PVRTLKLLLQEPSLAGPTQSGESTETAAENMYNAPPTFGHVHKMQGGSDFEDLVTSTNSLESG-E 816

  Fly   596 NHLQ 599
            :|.|
  Fly   817 DHPQ 820

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	150/635 (24%)
Nlg1	NP_001246966.1	COesterase	153..710	CDD:278561	143/599 (24%)
		Aes	<263..>408	CDD:223730	47/157 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810