Protein Alignment CG12869 and Nlg3

DIOPT Version :10

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_731170.2
• Gene: Nlg3 / 40912
• FlyBaseID: FBgn0083963
• Length: 1159
• Species: Drosophila melanogaster
• Alignment Length: 1014
• Identity: 216/1014 - (21%)
• Similarity: 340/1014 - (33%)
• Gaps: 369/1014 - (36%)

  Fly    31 IKLEQGDLIGLKVFPDGTR-GAVYAFLGIPYAQAPINELRFAPAKPSSSFNRTLQATTMQPLCPQ 94
            |....|.:.|:.|..||.. ..|.|:.|||||..|:..|||.|...::.::...:|....|:|||
  Fly   158 INTRNGAISGVIVQLDGRHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSPVCPQ 222

  Fly    95 LANTIYDESS-------------DGSMPRSVSTDEDCLYLNIWTP-ESGMR-------------- 131
            ....|::|::             ...:|...:..||||||||:.| :.|.|
  Fly   223 RLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSSSSAGSS 287

  Fly   132 -------------------------YGKLPIVVIVTGEEFAYDW-PRNRINGLDLAGEG-IVVVS 169
                                     ..|.|::|.|.||  :|:| ..|..:|..||..| |:||:
  Fly   288 SSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGE--SYEWNSGNPYDGSVLASYGQILVVT 350

  Fly   170 VQYRNNIYGWLSLG-EQHRNVPGNYGLSDVQMALRWIRRNADAFGGNPDHITLLGHGSGGAPLAL 233
            :.||..:.|:|:.. :::..:|.||||.|:..||.|::.|..||||:|:.|||.|||:|.   |.
  Fly   351 INYRLGVLGFLNANTDRYSKLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGA---AC 412

  Fly   234 VATLEDSSQVKQLVLMSPGPIMRALG-------QNHQKWIVETGQVLVQKLGCQFEEAQRRQLMG 291
            |..|..|..|.:.:|.:...:|...|       .|..|:    ..::...:.|. .:.....||.
  Fly   413 VHFLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAKY----AAIVAHHVNCA-SDLPHAHLMK 472

  Fly   292 CLRRKSREDLL---------------------------------------RAYESVYNHGNG-SS 316
            |||.|:.:.||                                       :|..|. ..||| ..
  Fly   473 CLREKTLDQLLSVPIRPPEFGFAFGPSIDGVVIDGGDYVPPAPGSPAAQAQAQAST-AAGNGLGG 536

  Fly   317 QLGVILPEGLPLEQRLRNKTLP-----------PVLLGITSNEGAFL-----QDYWLDVAREGQV 365
            :.|:....|.....:|.|..|.           .::.|:|..|..|.     ..|.::..|..::
  Fly   537 EAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAFFSFNSGDVQYGIEADRRSRI 601

  Fly   366 ALHKYINHTLLPNVMRALESVGEESSTQLAAIRWRYFNGKGEGVSH---LLAGMQRLLSESLYEL 427
             |..|:.:|...::.....::..|.:.      |.      ..|.|   :.......||::....
  Fly   602 -LKAYVRNTYTFHLNEIFATIVNEYTD------WE------RPVQHPINIRDETLEALSDAQVVA 653

  Fly   428 PYSRILEL--LNGTTSYAYVFDHSHSMDMRGRRNLFG------GASHSSDLPLLLGPSL---FQQ 481
            |.::.::|  .:...||.||||:         :..||      |..|..|||.:.|..|   |..
  Fly   654 PAAQTVDLHSADHRNSYLYVFDY---------QTRFGDYPQRQGCIHGEDLPYIFGAPLVGGFNH 709

  Fly   482 IARRRFSGEEEQLCRKIRGAFANFIKNGNPTPGRIYDGWLPYNKENPFVYSLGEQAKTPQTGS-- 544
            .. |.::..|..|...:...::||::.|||                      .||.:| :.||
  Fly   710 FT-RNYTKTEISLSEVVMFYWSNFVRTGNP----------------------NEQMET-EHGSRQ 750

  Fly   545 -----------VDEAEVDKLLRGETGAPGLDRSLSRSNR--------HDTYRAAPSNSYTASNQL 590
                       ..|:...|.|..:| .|.| ::..|::|        .|.::....|...|.:||
  Fly   751 ERSRYKTIEWTAYESVHKKYLNFDT-KPKL-KNHYRAHRLSFWLNLIPDLHKPGGDNVPAAHHQL 813

  Fly   591 --DSGYSNHL------------------------------QMVYGFWQVLMP---LEREEDLRGG 620
              |....|::                              ..|:....:..|   |:|.....||
  Fly   814 HDDDDEDNNIPSDASVKPLNPPYISRAANAAAMANFTIFTNQVFSLLNLSSPSSSLQRNGTRYGG 878

  Fly   621 GAL-------GQRVRLLEASADAARYRQGF--YAMLGLVCLLLACLCLCVYLLKRDPNAMRRRSA 676
            |.:       |...   ..:|.|::...||  |:....|.:.:.|..|.:.:|
  Fly   879 GKIYPDDMMDGDHA---GGAASASQDSDGFAAYSTALSVTIAIGCSLLILNVL------------ 928

  Fly   677 SSASDCYSLXHKWFRWTTIFGG---RKDEV------PSTSGIANVESWRKGGRATKREQDGSGAV 732
                              ||.|   ::|:.      |.|.              .||:
  Fly   929 ------------------IFAGVYYQRDKTRLSEPRPQTK--------------LKRQ------- 954

  Fly   733 ESGGGDGNLEGERR----------EQVLNKQRTRRPRQLQPYDF-KITH--------------PI 772
            |:|....|:.|:..          ..:|:.....:..||.|.:| .|.|              |
  Fly   955 ENGQMPNNICGDLETLTIHAKSDPATILSHHHAMQHHQLPPPEFADIPHRAPPPPKHMKSLQDP- 1018

  Fly   773 GGAGVGAGFGTGTAGGVRNGGGTRAGTVSGFGGTLGTVE 811
                               |||   |:|||..|..|.|:
  Fly  1019 -------------------GGG---GSVSGAVGVSGVVQ 1035

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	152/643 (24%)
Nlg3	NP_731170.2	COesterase	154..791	CDD:395084	162/691 (23%)