Protein Alignment CG12869 and alpha-Est3

DIOPT Version :10

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_524267.2
• Gene: alpha-Est3 / 40907
• FlyBaseID: FBgn0015571
• Length: 543
• Species: Drosophila melanogaster
• Alignment Length: 611
• Identity: 139/611 - (22%)
• Similarity: 225/611 - (36%)
• Gaps: 147/611 - (24%)

  Fly    27 QQTHIKLEQGDLIGLKVFPDGTRGAVY-AFLGIPYAQAPINELRFAPAKPSSSFNRTLQATTMQP 90
            :...:....|.::|.:.  .|..|..| :|..|||||.|:..|||....|...:::.|..|  :|
  Fly     2 ESLQVNTTSGPVLGKQC--TGVYGDEYVSFERIPYAQPPVGHLRFMAPLPVEPWSQPLDCT--KP 62

  Fly    91 LCPQLANTIYDESSDGSMPRSVSTDEDCLYLNIWTPE-SGMRYGKLPIVVIVTGEEFAYDWPRNR 154
            ....|....|.:..:|.        |||||||::..| ...|  .||::|...|..|....|...
  Fly    63 GQKPLQFNHYSKQLEGV--------EDCLYLNVYAKELDSPR--PLPLIVFFFGGGFEKGDPTKE 117

  Fly   155 INGLD-LAGEGIVVVSVQYRNNIYGWLSLGEQHRNVPGNYGLSDVQMALRWIRRNADAFGGNPDH 218
            ::..| .....:|||:|.||....|:|||.:....||||.||.|..:|:.||:.||:.|.|:|.:
  Fly   118 LHSPDYFMMRDVVVVTVSYRVGPLGFLSLNDPAVGVPGNAGLKDQLLAMEWIKENAERFNGDPKN 182

  Fly   219 ITLLGHGSGGAPLALVATLEDSSQVKQLVLMSPGPIMRALGQNHQKWIVETGQVLVQKLGCQFEE 283
            :|..|..:|.|.:             ..::::|    :|.|..| |.|:::|.||.....|..:.
  Fly   183 VTAFGESAGAASV-------------HYLMLNP----KAEGLFH-KAILQSGNVLCSWALCTIKN 229

  Fly   284 AQRR----------------QLMGCLRRKSREDLLRAY---------ESVYNHG----------- 312
            ...|                .::..|::...|.|:|.|         :.|:..|
  Fly   230 LPHRLAVNLGMESAEHVTDAMVLDFLQKLPGEKLVRPYLLSAEEHLDDCVFQFGPMVEPYKTEHC 294

  Fly   313 ---NGSSQLGVILPEGLPLEQRLRNKTLPPVLLGITSNEGAF------LQDYWLDVAREGQVALH 368
               |...:|         |::...|:.  |||:..||.||..      :..|.|       .:|.
  Fly   295 ALPNHPQEL---------LDKAWGNRI--PVLMSGTSFEGLLMYARVQMAPYLL-------TSLK 341

  Fly   369 KYINHTLLPNVMRAL-----ESVGEESSTQLAAIRWRYFNGKGEGVSHLLAGMQRLLSESL---- 424
            |...|.|..:|.|.|     ..:|:.       ::..:|.|.....         :..|||
  Fly   342 KEPEHMLPLDVKRNLPQALARHLGQR-------LQETHFGGNDPSA---------MSPESLKAYC 390

  Fly   425 ----YELPYSRILELL------NGTTSYAYVFDHSHSMDMRGRRNLFG----GASHSSDLPLLLG 475
                |::.:..||:.|      :..::|.|.||.........|....|    |.:|..|...|..
  Fly   391 EYASYKVFWHPILKTLRSRVKSSSASTYLYRFDFDSPTFNHQRLKYCGDKLRGVAHVDDHSYLWY 455

  Fly   476 PSLFQQIARRRFSGEEEQLCRKIRGAFANFIKNGNPTPGRIYD------GWLPYNKENPF-VYSL 533
            .....::.:..   .|.....::.....:|.:..||....|.|      .|.|.|.::.. ..::
  Fly   456 GDFSWKLDKHT---PEFLTIERMIDMLTSFARTSNPNCKLIQDQLPRAKEWKPLNSKSALECLNI 517

  Fly   534 GEQAKTPQTGSVDEAEVDKLLRGETG 559
            .|..|..:...:.:..|.:.:...||
  Fly   518 SENIKMMELPELQKLRVWESVCQSTG 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	136/591 (23%)
alpha-Est3	NP_524267.2	alpha/beta hydrolases	2..535	CDD:473884	136/601 (23%)