Protein Alignment CG12869 and Est-6

DIOPT Version :10

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_788500.1
• Gene: Est-6 / 39392
• FlyBaseID: FBgn0000592
• Length: 544
• Species: Drosophila melanogaster
• Alignment Length: 562
• Identity: 128/562 - (22%)
• Similarity: 227/562 - (40%)
• Gaps: 124/562 - (22%)

  Fly    31 IKLEQGDLIGLKVFPDGTRGAVYAFLGIPYAQAPINELRF-APAKPSSSFNRTLQATTMQPLCPQ 94
            ::|.||.|.|      ...|:.|::..||||:.|..:||| ||......::....||.....|.|
  Fly    30 VQLPQGKLRG------RDNGSYYSYESIPYAEPPTGDLRFEAPEPYKQKWSDIFDATKTPVACLQ 88

  Fly    95 LANTIYDESSDGSMPRSVSTDEDCLYLNIWTPESGMRYGKLPIVVIVTGEEFAYD--WPRNRING 157
                 :|:.:.|:  ..:..:||||.::::.|::..| ...|:|..:.|..|.:.  |.....|
  Fly    89 -----WDQFTPGA--NKLVGEEDCLTVSVYKPKNSKR-NSFPVVAHIHGGAFMFGAAWQNGHEN- 144

  Fly   158 LDLAGEG-IVVVSVQYRNNIYGWLSLGEQHRNVPGNYGLSDVQMALRWIRRNADAFGGNPDHITL 221
              :..|| .::|.:.||....|::|.|:  |::||||||.|.::||:||::|..:|||.|.::.|
  Fly   145 --VMREGKFILVKISYRLGPLGFVSTGD--RDLPGNYGLKDQRLALKWIKQNIASFGGEPQNVLL 205

  Fly   222 LGHGSGGAPLALVATLEDSSQVKQLVLMSPGPIMRALGQNHQKWIVETGQ-----VLVQKLGCQF 281
            :||.:|||.:.|....||..|:.:......|..:       ..|:::.|.     .|.:.:||:.
  Fly   206 VGHSAGGASVHLQMLREDFGQLARAAFSFSGNAL-------DPWVIQKGARGRAFELGRNVGCES 263

  Fly   282 EEAQRRQLMGCLRRKSREDLLRAYES--VYNHGNGSSQLGVILPEGLP---LEQRLRNKTLP--- 338
            .| ....|..||:.|...:|:.|...  ::::...:....|:.|...|   :.|..|:....
  Fly   264 AE-DSTSLKKCLKSKPASELVTAVRKFLIFSYVPFAPFSPVLEPSDAPDAIITQDPRDVIKSGKF 327

  Fly   339 ---PVLLGITSNEGAF-----------------LQDYWLDVA-----------REGQVALHKYIN 372
               |..:...:.:|.:                 |.:.||::|           ::......:.|.
  Fly   328 GQVPWAVSYVTEDGGYNAALLLKERKSGIVIDDLNERWLELAPYLLFYRDTKTKKDMDDYSRKIK 392

  Fly   373 HTLLPNVMRALESVGEESSTQLAAIRWRYFNGKGEGVSHLLAGMQRLLSESLYELPYSRILEL-- 435
            ...:.|....:||..|                           :|||.::.|::......|:|
  Fly   393 QEYIGNQRFDIESYSE---------------------------LQRLFTDILFKNSTQESLDLHR 430

  Fly   436 -LNGTTSYAYVFDH----SHSMDMRGRRNLFGGASHSSDLPLLLGPSLFQQIARR-RFSGEEEQL 494
             ...:.:||||:|:    ..:..:..|.:...|..|..|..|     :|:...|. ....:|:.:
  Fly   431 KYGKSPAYAYVYDNPAEKGIAQVLANRTDYDFGTVHGDDYFL-----IFENFVRDVEMRPDEQII 490

  Fly   495 CRKIRGAFANFIKNGNPTPGRIYDGWLPYNKENPFVYSLGEQ 536
            .|......|:|..:.|        |.|.|. |..|..::|.:
  Fly   491 SRNFINMLADFASSDN--------GSLKYG-ECDFKDNVGSE 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	128/562 (23%)
Est-6	NP_788500.1	Esterase_lipase	29..537	CDD:238191	128/562 (23%)