Protein Alignment CG12869 and Nlg3

DIOPT Version :10

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: XP_061500330.1
• Gene: Nlg3 / 3290865
• VectorBaseID: AGAMI1_000316
• Length: 952
• Species: Anopheles gambiae
• Alignment Length: 949
• Identity: 223/949 - (23%)
• Similarity: 328/949 - (34%)
• Gaps: 290/949 - (30%)

  Fly    25 SAQQTHIKLEQGDLIGLKVFPDGTR-GAVYAFLGIPYAQAPINELRFAPAKPSSSFNRTLQATTM 88
            |::..|.|  .|.:.|.....||.. ..|.||.|:|||..|:..|||.|....:.::...:|...
Mosquito    62 SSRIVHTK--YGAVSGTIEHLDGRHLDPVEAFRGVPYASPPVGNLRFMPPVTGALWSGVKKADRF 124

  Fly    89 QPLCPQLANTIYDESSD-GSMPRS------------VSTDEDCLYLNIWTP-ESGMR----YGKL 135
            .|:|||....||:|::. ..|||.            .:..||||||||:.| ::|.|    ..|.
Mosquito   125 SPVCPQRLPDIYNETAALERMPRGRLEYLRRLLPYLRNQSEDCLYLNIYVPTQAGSRESSSTSKY 189

  Fly   136 PIVVIVTGEEFAYDW-PRNRINGLDLAGEG-IVVVSVQYRNNIYGWLSLG-EQHRNVPGNYGLSD 197
            .:||.|.||  :|:| ..|..:|..||..| |:||::.||..|.|:|:.. ::....|.||||.|
Mosquito   190 AVVVFVHGE--SYEWNSGNPYDGSVLASYGQILVVTINYRLGILGFLNANVDRFSKAPANYGLMD 252

  Fly   198 VQMALRWIRRNADAFGGNPDHITLLGHGSGGAPLALVATLEDSSQVKQLVLMSPGPIMRALGQNH 262
            :..||.||:.|.:||||:|..:||.|||:|.   |.|..|..|:.|.:.:|.....:|...|...
Mosquito   253 IIAALHWIQENIEAFGGDPKSVTLAGHGTGA---ACVHFLIASAAVPEGLLFHRAIMMSGSGLAP 314

  Fly   263 QKWIVETGQ---VLVQKLGCQFEEAQRRQLMGCLRRKSREDLLRAYESVYNHGN--GSSQLGVIL 322
            ...:.|..:   .:...:.|. .:...:.|:.|||.|..||:|.......:.||  |.|..||::
Mosquito   315 WSLVGEPAKFAAYVSHHVNCS-PDLPHQLLLKCLRDKPLEDILSTSVRAPDFGNAFGPSVDGVVI 378

  Fly   323 PEGLPLEQ--------------------RLRN--KTLPPVLL---------------GITSNEGA 350
            ..| .::|                    .:.|  .|:..:||               |:|..|..
Mosquito   379 DTG-EIQQMDGTHYSDYSGNPAATKPSAHIHNTLNTINAILLRKLAINKLSKYDLLVGVTRAEAY 442

  Fly   351 FL---QD--YWLDVAREGQVALHKYINHTLLPNVMRALESVGEESSTQLAAIRWRYFNGKGEGVS 410
            |.   :|  |.::..|..:: |..|:..|...::...|.::..|.:.      |.      ..|.
Mosquito   443 FAFNSEDVQYGIEADRRAKI-LKNYVRSTYSFHLNEILATIVNEYTD------WE------RPVQ 494

  Fly   411 HLLAGMQRLLSESLYELPYSRI---------LELLNGTTSYAYVFDHSHSMDMRGRRNLFG---- 462
            |.:    .:..|:|..|..:||         |...:...|:.||||:         :..||
Mosquito   495 HPI----NIRDETLEALSDARIVAPAVQTADLHSADHRNSFLYVFDY---------QTKFGDFPQ 546

  Fly   463 --GASHSSDLPLLLGPSL---FQQIARRRFSGEEEQLCRKIRGAFANFIKNGNPTPGRIYD---- 518
              |..|..|||.|.|..|   |.... |.::..|..|...:...::|||:.|||......|
Mosquito   547 RQGCIHGEDLPYLFGAPLVGGFNHFT-RNYTKSEIALSEAVMIYWSNFIRTGNPNEQLENDHVRD 610

  Fly   519 -------GWLPYNKENPFVYSLGEQAKTPQTGSVDEAEVDKLLRGETGAPGLDRSLSRSNRHDTY 576
                   .|.||                       |:...|.|       .||......|.:..:
Mosquito   611 RTRFKNIEWTPY-----------------------ESVHKKYL-------NLDTKPKLKNHYRAH 645

  Fly   577 RAAPSNSYTASNQLDSGYSNHLQMVYGFWQVLMP--------------LEREEDLRGGGALGQRV 627
            |.:                        ||..|:|              .|.|.|.....|....|
Mosquito   646 RLS------------------------FWLNLVPDLHKPGNDDVPSGHHELESDDEEQPAALPTV 686

  Fly   628 RLLEASADAARYRQGFYAMLGLVCLLLACLCLCVYLLKRDPNAMRRRSASSASDCYSLXHKWFRW 692
            :.|...                               :|||..:........:..:|| :  |..
Mosquito   687 KPLNPP-------------------------------QRDPATIGSNYTLFTTQVFSLLN--FSS 718

  Fly   693 TTIFGGRKDEVPSTSGI--ANVESWRKGGRATKREQDGSGAVESGGGDGNLEGERRE-------- 747
            ..|........|.|..:  ...|| .:||     :.||..|....||.|.:...:.:
Mosquito   719 YGILPNGSRHYPGTRPVHPVTAES-SEGG-----DDDGGAAGGGAGGAGGMSSSQEDGFAAYSTA 777

  Fly   748 -----------QVLN------------KQRTRRPRQLQPYDFKITHPIGGAGVGAGFGTGT-AGG 788
                       .:||            |.|...||.            ||.|:|...|.|| ...
Mosquito   778 LSVTIAIGCSLLILNVLIFAGVYYQRDKTRLNEPRG------------GGPGMGGPGGHGTLQTK 830

  Fly   789 VRNGGGTRAGTVSGFGGTLGTVEELLDP--VAGQFEPSV 825
            .||..|.....:.|...:| |:....||  :.|...|::
Mosquito   831 KRNENGQMPNNICGELESL-TIHAKADPSTILGHHHPAL 868

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	163/611 (27%)
Nlg3	XP_061500330.1	None