Protein Alignment CG12869 and Ces5a

DIOPT Version :9

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_001012056.2
• Gene: Ces5a / 307660
• RGDID: 1549717
• Length: 575
• Species: Rattus norvegicus
• Alignment Length: 543
• Identity: 140/543 - (25%)
• Similarity: 225/543 - (41%)
• Gaps: 141/543 - (25%)

  Fly    52 VYAFLGIPYAQAPINELRFAPAKPSSSFNRTLQATTMQPLCPQLAN--TIYDESSDGSMPRSVST 114
            |..|||||:|..|:..|||:..:|...::...:|||...:|.|...  .||........|: :..
  Rat    54 VNVFLGIPFAAPPLGPLRFSNPQPPIPWHDLREATTYPNVCFQNLEWLFIYQNLLKVHYPK-LGV 117

  Fly   115 DEDCLYLNIWTPESGMRYGKLPIVVIV------TGEEFAYDWPRNRINGLDLAG-EGIVVVSVQY 172
            .||||||||:.|.......:||:::.:      ||....:|       |..||. |.:::|::||
  Rat   118 SEDCLYLNIYAPAYANDGSRLPVMMWIPGGGFETGSASIFD-------GSALAAYEDVLIVTIQY 175

  Fly   173 RNNIYGWLSLGEQHRNVPGNYGLSDVQMALRWIRRNADAFGGNPDHITLLGHGSGGAPLALVATL 237
            |..|:|:.:...||  .|||:...|...||:|:|.|.:.||||||.:|:.| ||.||
  Rat   176 RLGIFGFFNTQNQH--APGNWAFQDQLAALQWVRENINYFGGNPDSVTIFG-GSAGA-------- 229

  Fly   238 EDSSQVKQLVL--MSPGPIMRALGQNHQKWIVETGQVLVQKLG----------------CQFEEA 284
               ..:..|:|  :|.|...||        |:::|..::..|.                |:...:
  Rat   230 ---ISISSLILSPLSAGLFHRA--------IMQSGVAIIPSLKNFDDELKHGLQVVADVCKCNVS 283

  Fly   285 QRRQLMGCLRRKSREDLL------RAYESVYNHGNGSSQLGVILPEGLPLEQRLRNKTLP--PVL 341
            ..:.|:.|||.||..:||      :|:..|.:        |...||. |:| .|..||..  |.:
  Rat   284 DSKVLLKCLREKSSLELLSLGQKTKAFTRVVD--------GSFFPEE-PME-LLSQKTFKTVPSI 338

  Fly   342 LGITSNEGAFLQDYWLDVAREGQVALHKYINHTLLPNVMRALESV--GEESSTQLAAIR------ 398
            :|:.:.|..:                       :||  ||....:  |...||.|..|.
  Rat   339 IGVNNQECGY-----------------------ILP--MREAPEILFGSNESTALTLIHVLLHIP 378

  Fly   399 --------WRYFNGKGEGVSHLLAGMQRLLSESLYELPYSRILELLNGTTS-----------YAY 444
                    ..||:||     |.|..::    ::|.:| :..:..::.|..:           |.|
  Rat   379 PQYMHIVAKDYFHGK-----HSLTDIR----DTLLDL-FGDVFFVVPGLVTARNHRDAGGPVYFY 433

  Fly   445 VFDHSHSMDMRGRRNLFGGASHSSDLPLLL-GPSLFQQIARRRFSGEEEQ-LCRKIRGAFANFIK 507
            .|.|..:. .:..|..|..|.|:.::..:. ||.|...:.....:.|:|: |.||:...:|||.:
  Rat   434 EFQHRPNC-FQNTRPAFVKADHTDEIRFVFGGPFLEGDVVMFEEATEDEKLLSRKMMSYWANFAR 497

  Fly   508 NGNPTPGRIYDGWLPYNKENPFV 530
            :|:|. |.....|..|::...::
  Rat   498 SGDPN-GDDLPLWPAYDQNESYL 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	140/543 (26%)
Ces5a	NP_001012056.2	Esterase_lipase	40..529	CDD:238191	140/543 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D233524at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.920