Protein Alignment CG12869 and Ces1e

DIOPT Version :9

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_113753.2
• Gene: Ces1e / 29225
• RGDID: 621508
• Length: 561
• Species: Rattus norvegicus
• Alignment Length: 585
• Identity: 159/585 - (27%)
• Similarity: 246/585 - (42%)
• Gaps: 141/585 - (24%)

  Fly    35 QGDLIGLKVFPDGTRGAVYAFLGIPYAQAPINELRFAPAKPSSSFNRTLQATTMQPLC---PQLA 96
            ||.::|..|..:|....|..|||:|:|:.|:..|||||.:|:..::.....|:..|:|   |...
  Rat    30 QGKVLGKYVSLEGFTQPVAVFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTSYPPMCSQDPVAG 94

  Fly    97 NTIYDESSDGSMPRSVSTDEDCLYLNIWTPESGMRYGKLPIVV------IVTGEEFAYDWPRNRI 155
            ..:.|..::.....|:...||||||||:||....:..:||::|      :|.|....||
  Rat    95 QIVNDLLTNREENISLQFSEDCLYLNIYTPADLTKRDRLPVMVWIHGGGLVLGGASTYD------ 153

  Fly   156 NGLDLA-GEGIVVVSVQYRNNIYGWLSLGEQHRNVPGNYGLSDVQMALRWIRRNADAFGGNPDHI 219
             ||.|: .|.:|||.:|||..|:|:.|.|::|..  ||:|..|...||.|::.|.|.|||:|..:
  Rat   154 -GLALSTHENVVVVVIQYRLGIWGFFSTGDEHSR--GNWGHLDQVAALHWVQDNIDNFGGDPGSV 215

  Fly   220 TLLGHGSGGAPLALVATLEDSSQVKQLVLMSPGPIMRALGQNHQKWIVETGQVLVQKL------- 277
            |:.|..:||            ..|..|||   .|:.:.|   ..|.|.|:|..|...|
  Rat   216 TIFGESAGG------------ESVSVLVL---SPLAKNL---FHKAISESGVALTAGLVKKNTRP 262

  Fly   278 ---------GCQFEEAQRRQLMGCLRRKSREDLLRA-----YESVYNHGNGSSQL--------GV 320
                     ||  :......::.|||:|:.|:||..     ..|:..||:.....        ||
  Rat   263 LAEKIAVVSGC--KSTTSAAMVHCLRQKTEEELLETTLKLNLFSLDLHGDSRQSYPFVPTVLDGV 325

  Fly   321 ILPEGLPLEQRLRNK--TLPPVLLGITSNEGAFL-------------------------QDYWLD 358
            :||: :| |:.|..|  ...|.::||...|..::                         ..:.|:
  Rat   326 VLPK-MP-EEILAEKDFNTVPYIVGINKQEFGWILPTMMNYPPSDMKLDPMTATSLLKKSSFLLN 388

  Fly   359 VAREG-QVALHKYINHTLLP--NVMRALESVGEESSTQLAAIRWRYFNGKGEGVSHLLAGMQRLL 420
            :..|. .||:.||:.||..|  |..:.||.:|:......:.|..|         .|..||.:..:
  Rat   389 LPEEAIPVAVEKYLRHTDDPDRNKDQLLELIGDVIFGVPSVIVSR---------GHRDAGARTYM 444

  Fly   421 SESLYELPYSRILELLNGTTSYAYVFDHSHSMDMRGRRNLFGGASHSSDLPLLLGPSLFQQIARR 485
            .|..|...:|..::      ....|.||...:     .::||.       |:|.|.:
  Rat   445 YEFQYRPSFSSKMK------PSTVVGDHGDEI-----YSVFGA-------PILRGGT-------- 483

  Fly   486 RFSGEEEQLCRKIRGAFANFIKNGNPTPGRIYDGWLPYNKENPFVYSLGEQAKTPQTGSVDEAEV 550
              |.||..|.:.:...:|||.:||||. |:....|..|:::..:: .:|  |.|.|...:.|.||
  Rat   484 --SKEEINLSKMMMKFWANFARNGNPN-GQGLPHWPEYDQKEGYL-QIG--ATTQQAQKLKEKEV 542

  Fly   551  550
              Rat   543  542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	155/574 (27%)
Ces1e	NP_113753.2	COesterase	24..545	CDD:278561	159/585 (27%)
		Aes	43..>239	CDD:223730	73/219 (33%)
		Prevents secretion from ER (Potential)	558..561

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010