Protein Alignment CG12869 and Ces2g

DIOPT Version :10

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_001099645.1
• Gene: Ces2g / 291952
• RGDID: 1308358
• Length: 560
• Species: Rattus norvegicus
• Alignment Length: 642
• Identity: 176/642 - (27%)
• Similarity: 255/642 - (39%)
• Gaps: 163/642 - (25%)

  Fly     2 W-NALRIQQILRLLPILIHL----SPYIS-AQQTHIKLEQGDLIGLKVFPDGTRGAVYAFLGIPY 60
            | ||:    :..||.:|||:    ||..| .:.||....||.|...|.|..|    |:.|||||:
  Rat     9 WLNAV----LFGLLLLLIHVQGQHSPESSPIRNTHTGQVQGKLTHSKDFKSG----VHTFLGIPF 65

  Fly    61 AQAPINELRFAPAKPSSSFNRTLQATTMQPLCPQLANTIYDESSDG------SMPRSVSTDEDCL 119
            |:||:..|||||.:....::.....|:...:|||....    :.:|      ::| .||..||||
  Rat    66 AKAPVGPLRFAPPEAPEPWSGVRDGTSQSNICPQNVRM----NMEGLKEMKLTLP-PVSMSEDCL 125

  Fly   120 YLNIWTPESGMRYGKLPIVV------IVTGEEFAYDWPRNRINGLDLAGEGIVVVSVQYRNNIYG 178
            ||||:.|........||::|      :..|....||      ..:..|.|.:|||::|||..:.|
  Rat   126 YLNIYAPAHAHEGSHLPVMVWIHGGALTVGMASMYD------GSMLAATEDVVVVTIQYRLGVLG 184

  Fly   179 WLSLGEQHRNVPGNYGLSDVQMALRWIRRNADAFGGNPDHITLLGHGSGGAPLALVATLEDSSQV 243
            :.|.|:.|..  ||:|..|...||||:::|...||||||.:|:.|..:||        |..||.|
  Rat   185 FFSTGDHHAR--GNWGYLDQVAALRWVQQNIAHFGGNPDCVTIFGESAGG--------LSVSSHV 239

  Fly   244 KQLVLMSPGPIMRALGQNHQKWIVETG----------------QVLVQKLGCQFEEAQRRQLMGC 292
              :..||.|...||        |:|:|                |::|:..||  |......|:.|
  Rat   240 --VSPMSKGLFHRA--------IMESGVALMPGTIFNFSEMVYQMVVKLSGC--EAMDPESLVHC 292

  Fly   293 LRRKSRE---------DLLRAY---ESVYNH-----------------GNGSSQLGVILPEGLPL 328
            ||.||.|         .::.|.   |.:.||                 |..:.:.|.|:|:.:..
  Rat   293 LRGKSEEQITVISKEFQMIPAVVDGEFLPNHPQELLASADFHPVPSIIGFNNDEYGWIVPKVIGS 357

  Fly   329 EQRLRNKTLPPVLLGIT-SNEGAFLQDYWLDVAREGQVALHKYINHTLLPNVMRALESVGEESST 392
            .|.::         ||| .|..|||:|      ...|:.|....:..|:...|
  Rat   358 AQTIK---------GITRENLQAFLKD------TAPQMMLPPECSDLLMEEYM------------ 395

  Fly   393 QLAAIRWRYFNGKGEGVSHLLAGMQRLLSESLYELPYSRILELLNG-TTSYAYVFDHSHSMDMRG 456
                       |..|....|.|....::.:.::.:|..::...... ...|.|.|.|..|. ::.
  Rat   396 -----------GDIEDPQTLQAQFTEMMEDFMFVIPSLQVARFQRSHAPVYFYEFQHQSSF-LKD 448

  Fly   457 RRNLFGGASHSSDLPLLLGPSLFQQIARRRFSGEEEQLCRKIRGAFANFIKNGNPTPGRIYDGWL 521
            .|.....|.|..::|.:.| |.|..:......| |:.|.|::...:|||.:.|||....     |
  Rat   449 IRPPHVKADHGDEVPFVFG-SFFWGMKLNLTEG-EKLLNRRMMKYWANFARYGNPNSNS-----L 506

  Fly   522 PYNKENPFVYSLGEQ----AKTPQTGSVDEAEVDKLLRGETGAPGLDRSLSRS-NRH 573
            ||..    |:...||    ...|..|.:.:|.  ||.......|.....|.|| |.|
  Rat   507 PYWP----VFDYDEQYLQLNTQPAVGRIQKAR--KLQFWTKTLPQKIEELKRSQNMH 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	154/576 (27%)
Ces2g	NP_001099645.1	COesterase	32..539	CDD:395084	160/595 (27%)