Protein Alignment CG12869 and Ces4a

DIOPT Version :10

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_666325.2
• Gene: Ces4a / 234677
• MGIID: 2384581
• Length: 563
• Species: Mus musculus
• Alignment Length: 608
• Identity: 148/608 - (24%)
• Similarity: 241/608 - (39%)
• Gaps: 158/608 - (25%)

  Fly     2 WN-----------ALRIQQILRLL----PILIHLSPYISAQQTHIKLEQGDLIGLKVFPDGTRGA 51
            ||           .|.:|..|..|    |:||.....:..:|.|:    ||.            .
Mouse     6 WNMKWILGLSLTLCLVVQTALGALHTKEPLLITKHGILQGKQVHV----GDT------------P 54

  Fly    52 VYAFLGIPYAQAPINELRFAPAKPSSSFNRTLQATTMQPLCPQLANTIYDESSDGSMPRSVST-- 114
            :..|||||:::.|:...||||.:|...:|....|||..|.|.|       ||....:...::|
Mouse    55 IQVFLGIPFSKPPVGTRRFAPPEPPLPWNGIRDATTYPPSCLQ-------ESWGQILSMYLNTRK 112

  Fly   115 -------DEDCLYLNIWTPESGMRYGKLPIVV------IVTGEEFAYDWPRNRINGLDLAGEG-I 165
                   .|||||||::.|........||::|      .:.|....|:       |.:||..| :
Mouse   113 QYKWLHFSEDCLYLNVYAPVLAPGAPLLPVMVWFPGGAFLAGSASTYE-------GSELAARGKV 170

  Fly   166 VVVSVQYRNNIYGWLSLGEQHRNVPGNYGLSDVQMALRWIRRNADAFGGNPDHITLLGHGSGG-- 228
            |:|.:|||..|.|:.|.|..|..  ||:||.|...||||::.|.:||||:||.:||.|..:|.
Mouse   171 VLVFLQYRLGILGFFSTGNSHAR--GNWGLLDQIAALRWVQENIEAFGGDPDSVTLFGQSAGAMS 233

  Fly   229 ------APLALVATLEDSSQVKQLVL---MSPGPIMRALGQNHQKWIVETGQVLVQKLGCQFEEA 284
                  :|||.....:..||....||   ::|.|:..|             :.:....||  :..
Mouse   234 VSGLMVSPLAQGLFHQAISQSGTAVLKAFITPDPLTSA-------------KKIAHLAGC--DHN 283

  Fly   285 QRRQLMGCLRRKSREDLL-----RAYESVYNHGNGSSQL--------GVILPEGLPLEQRLRNKT 336
            ..:.::.|||..|.|::.     .::....:|.:....:        ||:.||. |:....|.:.
Mouse   284 STKVMVECLRSLSAEEVTLVSKRMSFFQANSHKDPKEIVWFLSPVVDGVVFPED-PVVLLTRGQV 347

  Fly   337 LP-PVLLGITSNEG----AFLQDYWLDVAREGQVALHKYI-NHTLLPNVMRALESVGEESSTQLA 395
            .| |.|||:.:.|.    .||....|:.....|..::|.: :..:|.|:          :..|:.
Mouse   348 KPVPYLLGVNNAEFEWNLPFLMKIQLNQRMMNQTNINKILWSFNVLLNI----------TKEQVP 402

  Fly   396 AIRWRYFNGKGEGVSHLLAGMQRLLSESLYELPYSRILELLN------------------GTTSY 442
            .:...|.|.              .:|...:::..:|:::|:.                  |:..|
Mouse   403 VVAREYLND--------------AISNHDWKMFRNRLIDLIGDATFVYATLQAARYHRDAGSPVY 453

  Fly   443 AYVFDHSHSMDMRGRRNLFGGASHSSDLPLLLGPSLFQQIARRRFSGEEEQLCRKIRGAFANFIK 507
            .|.|.|..|..:..:.  :.||.|..:|..|.|    ...::...:|||::...::...:|||..
Mouse   454 LYEFKHHASSGIIIKP--YNGADHGDELSYLFG----SPFSKGSSAGEEKEFSLQMMKYWANFAH 512

  Fly   508 NGNPTPGRIYDGWLPYNKENPFV 530
            .|||. |.....|..::|:..::
Mouse   513 TGNPN-GEKLPYWPRFDKDEKYL 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	139/568 (24%)
Ces4a	NP_666325.2	COesterase	33..554	CDD:395084	142/581 (24%)