Protein Alignment CG12869 and Ces2e

DIOPT Version :10

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_766347.1
• Gene: Ces2e / 234673
• MGIID: 2443170
• Length: 559
• Species: Mus musculus
• Alignment Length: 543
• Identity: 153/543 - (28%)
• Similarity: 249/543 - (45%)
• Gaps: 84/543 - (15%)

  Fly    13 LLPILIHLSPYISA---QQTHIKLEQGDLIGLKVFPDGTRGAVYAFLGIPYAQAPINELRFAPAK 74
            :|.:::|:....||   :.||....:|.|:.:|    .|..||:.|||||:|:.|:..|||||.:
Mouse    17 VLLLVLHVQGQDSASPIRNTHTGQVRGSLVHVK----DTDIAVHTFLGIPFAKPPVGPLRFAPPE 77

  Fly    75 PSSSFNRTLQATTMQPLCPQLANTIYDESSDGSMPR----SVSTDEDCLYLNIWTPESGMRYGKL 135
            ....::.....|:...:|.|..|.:  .|.|..|..    .:|..||||||||:.|........|
Mouse    78 APEPWSGVRDGTSHPNMCLQNDNLM--GSEDLKMMNLILPPISMSEDCLYLNIYVPAHAHEGSNL 140

  Fly   136 PIVV------IVTGEEFAYDWPRNRINGLDLAGEGIVVVSVQYRNNIYGWLSLGEQHRNVPGNYG 194
            |::|      :..|....||      ..:..|.|.:|||::|||..:.|:.|.|:||  ..||:|
Mouse   141 PVMVWIHGGALTVGMASMYD------GSMLAATEDVVVVAIQYRLGVLGFFSTGDQH--AKGNWG 197

  Fly   195 LSDVQMALRWIRRNADAFGGNPDHITLLGHGSGGAPLALVATLEDSSQVKQLVLMSP-------G 252
            ..|...||||:::|...||||||.:|:.|..:||..:        ||.|     :||       |
Mouse   198 YLDQVAALRWVQQNIVHFGGNPDRVTIFGESAGGTSV--------SSHV-----VSPMSQGLFHG 249

  Fly   253 PIMRALGQNHQKWIVETGQVLVQKL-----GCQFEEAQRRQLMGCLRRKSREDLLRAYESVYNHG 312
            .||.: |......::.:...:|.::     ||....::  .||.|||.|:..::| |...|:
Mouse   250 AIMES-GVAVLPDLISSSSEMVHRIVANLSGCAAVNSE--TLMCCLRGKNEAEML-AINKVF--- 307

  Fly   313 NGSSQLGVILPEGLPL--EQRLRNKTLPPV--LLGITSNEGAFLQDYWLDVAREGQVALHKYINH 373
              ....||:..|.||.  ::.:.:|...||  ::||.::|..::....:|.|::     .:.|..
Mouse   308 --KIIPGVVDGEFLPKHPQELMASKDFHPVPSIIGINNDEYGWILPTIMDPAQK-----IEEITR 365

  Fly   374 TLLPNVMR--ALESVGEESSTQLAAIRWRYFNGKGEGVSHLLAGMQRLLSESLYELPYSRILELL 436
            ..||.|::  ||:.:   ...:...:....:.|..|....|.|..:.:..:.::.:|..::....
Mouse   366 KTLPAVLKSTALKMM---LPPECGDLLMEEYMGDTEDPETLQAQFREMKGDFMFVIPALQVAHFQ 427

  Fly   437 NG-TTSYAYVFDHSHSMDMRGRRNLFGGASHSSDLPLLLGPSLFQQIARRRFSGEEEQLCRKIRG 500
            .. ...|.|.|.|..|. .:..|..:..|.|..::.|:.|.. |..| :..::.|||||.|:|..
Mouse   428 RSHAPVYFYEFQHRPSF-FKDFRPPYVKADHGDEIFLVFGYQ-FGNI-KLPYTEEEEQLSRRIMK 489

  Fly   501 AFANFIKNGNPTPGRIYDGWLPY 523
            .:|||.::|||..    :| |||
Mouse   490 YWANFARHGNPNS----EG-LPY 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	149/526 (28%)
Ces2e	NP_766347.1	COesterase	30..538	CDD:395084	150/530 (28%)