Protein Alignment CG12869 and Ces2b

DIOPT Version :10

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_937814.1
• Gene: Ces2b / 234669
• MGIID: 2448547
• Length: 556
• Species: Mus musculus
• Alignment Length: 557
• Identity: 152/557 - (27%)
• Similarity: 243/557 - (43%)
• Gaps: 115/557 - (20%)

  Fly    13 LLPILIHL----SPYIS-AQQTHIKLEQGDLIGLKVFPDGTRGAVYAFLGIPYAQAPINELRFAP 72
            ||.:|.|:    ||..| .:.||....:|.|:.:|    .|:..|:.|||||:|:.|:..|||||
Mouse    17 LLLLLGHVQGQDSPEASPIRNTHTGQVRGSLVHVK----DTKAGVHTFLGIPFAKPPVGPLRFAP 77

  Fly    73 AKPSSSFNRTLQATTMQPLCPQLANTIYDESSDGSMPRSVSTDEDCLYLNIWTPESGMRYGKLPI 137
            .:....::.....|....:|  |.|....:.....:| .|||.||||||||:||........||:
Mouse    78 PEAPEPWSGVRDGTAHPAMC--LQNLGVMKEIKLKLP-PVSTSEDCLYLNIYTPAHAHEGSNLPV 139

  Fly   138 VV------IVTGEEFAYDWPRNRINGLDLAGEGIVVVSVQYRNNIYGWLSLGEQHRNVPGNYGLS 196
            :|      :|.|....||      ..|..|.|.:|||::|||..:.|:.|.|:||..  ||:|..
Mouse   140 MVWIHGGGLVAGMASMYD------GSLLAAIEDLVVVTIQYRLGVLGFFSTGDQHAR--GNWGFL 196

  Fly   197 DVQMALRWIRRNADAFGGNPDHITLLGHGSGGAPLALVATLEDSSQVKQLVLMSP-------GPI 254
            |...|||||::|...|||.||.:|:.|..:||..:        ||.|     :||       |.|
Mouse   197 DQVAALRWIQQNIAHFGGKPDRVTIFGESAGGTSV--------SSHV-----VSPMSKGLFHGAI 248

  Fly   255 MRALGQNHQKWIVETGQVL---VQKL-GCQFEEAQRRQLMGCLRRKSREDLLRAYESVYNHGNGS 315
            |.:........|.:|.:::   |.|| ||:..:::  .|:.|||.||..::|...:.|
Mouse   249 MESGVALLPYLITDTSEMVSTTVAKLSGCEAMDSE--ALVRCLRGKSEAEILAINKLV------- 304

  Fly   316 SQL--GVILPEGLPL--EQRLRNKTLPPV--LLGITSNEGAFLQDYWLDVAREGQVALHKYINHT 374
             |:  .|:..|..|.  ::.|.::...||  ::|:.::|..     |
Mouse   305 -QMIPAVVDGEFFPRHPKELLASEDFHPVPSIIGVNNDEFG-----W------------------ 345

  Fly   375 LLPNVMRALESVGEESSTQLAAI-----------------RWRYFNGKGEGVSHLLAGMQRLLSE 422
            .:|.||.:.:::.|.:...|.|:                 ....:.|..|....|......::.:
Mouse   346 TIPVVMGSAQTIKEITRENLQAVLKNTTAQLMLPPECSDLLMEEYMGDTEDAQTLQIQFTEMMED 410

  Fly   423 SLYELPYSRILELLNGTTS-YAYVFDHSHSMDMRGRRNLFGGASHSSDLPLLLGPSLFQQIARRR 486
            .::.:|..::........| |.|.|.|..: .::..|.....|.|:.::|.:.|  .|....:..
Mouse   411 FMFVIPALQVAYFQRSHASVYFYEFQHQIA-SLKDVRPTHVKADHADEIPFVFG--YFFWDMKLD 472

  Fly   487 FSGEEEQLCRKIRGAFANFIKNGNPTPGRIYDGWLPY 523
            |:..|:.|.|::...:|||.::|||..    :| |||
Mouse   473 FTEGEKLLSRRMMKYWANFARHGNPNS----EG-LPY 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	145/538 (27%)
Ces2b	NP_937814.1	COesterase	32..535	CDD:395084	146/542 (27%)