Protein Alignment CG12869 and cest-31

DIOPT Version :10

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_504692.3
• Gene: cest-31 / 187304
• WormBaseID: WBGene00019653
• Length: 541
• Species: Caenorhabditis elegans
• Alignment Length: 599
• Identity: 152/599 - (25%)
• Similarity: 241/599 - (40%)
• Gaps: 144/599 - (24%)

  Fly    19 HLS-----PYISAQQTHIKLEQGDLIGLKVFPDGTRGAVYAFLGIPYAQAPINELRFAPAKPSSS 78
            |||     |.::...:.....||:|     :..|.. .|:.:|||||||.||..|||.....:..
 Worm     4 HLSHLKPKPLLNVLNSTCGPVQGNL-----YRHGNE-EVHGYLGIPYAQPPIGILRFKKPVSADV 62

  Fly    79 FNRTLQATTMQPLCPQLANTIYDESSDGSMPRSVSTDE-DCLYLNIWTPESGMRY-GKLPIVVIV 141
            :..|...|...|.||. :..:|:..   .:|.:...|| :||.||::.|:..::. .|.|:::.:
 Worm    63 WTETRDCTKYGPRCPP-SGMLYENL---QLPNTDIPDEANCLSLNVFCPQWEIKQSAKHPVMIFI 123

  Fly   142 TGEEF----AYDWPRNRINGLDLAGEGIVVVSVQYRNNIYGWLSLGEQHRNVPGNYGLSDVQMAL 202
            .|..|    :.|:....::| .|..:.::||:|.||....|:|:.|:.  :..||:||.|:.:||
 Worm   124 HGGGFELSASKDYCDYSLSG-TLPLKDVIVVTVNYRVGALGFLTTGDD--SCRGNFGLWDLTLAL 185

  Fly   203 RWIRRNADAFGGNPDHITLLGHGSGGAPLALVATLEDSSQ--VKQLVLMSPGPIMRALGQNHQKW 265
            :|:..:..:|||:|.::||.|. |.||..|.:..|...|:  ..:|::||        |..|..:
 Worm   186 KWVSTHISSFGGDPKNVTLFGQ-SAGAVCADLLNLSPYSRDLFHKLIIMS--------GSAHVPF 241

  Fly   266 IVETGQVLVQKLGCQFEEAQRRQLMGCLRRKSREDLLRAYESV----------YNHGNGSSQL-- 318
            .:.|.:  .|.|.| .|.|:.|...|    ....:||..:|::          ..| ..|..|
 Worm   242 AIRTEE--NQALVC-MEYARSRGFSG----SGSAELLEFFENLPIEKLLEKTGLKH-TVSIDLSF 298

  Fly   319 -----GVILPEGLPLEQRLRNKTLPPVLLGITSNEG---AFL----------------QDYWLDV 359
                 |...|:  |||:..|.....||::|:..:||   ||.                .:|..||
 Worm   299 APNLDGDFFPK--PLEELRRETRKKPVIVGMMEDEGLITAFADGDFTTCEENFKRRVESEYRGDV 361

  Fly   360 AREGQVALHKYINHTLLPNVMRALESVGEESSTQLAAIRWRYFNGKGEGVSHLLAGMQRLLS-ES 423
            ....:         .:..|:|....:..:||..:...          :.:.|.:.....||| ||
 Worm   362 VENPE---------NVQKNIMNFYTNYCDESEERKLV----------DYIGHSVYNAGVLLSAES 407

  Fly   424 LYELPYSRILELLNGTTSYAYVFD--HSHSMDMRGRRNLFGGASHSSDLPLLLGPSLFQQIARRR 486
            |...          |...|.||||  :.......|....|.||:|.|:|..::|..::.     :
 Worm   408 LARA----------GNCVYFYVFDFWNPDGFGPVGSIVPFKGAAHCSELRYIIGEGVYS-----K 457

  Fly   487 FSGEEEQL--CRKIRGAFANFIKNGNPT-PGRIYDGWLPYN-------------------KEN-- 527
            |...|:.|  ...:...|.||.|.|||. ||  ...|..|.                   :||
 Worm   458 FDANEKDLKMMEYMTTMFTNFAKYGNPNIPG--VTNWETYTEGSRHFHIDSTDSEMKDSFQENRC 520

  Fly   528 PFVYSLGEQAKTPQ 541
            .|:..:.||:|..|
 Worm   521 QFLKQIQEQSKRYQ 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	147/584 (25%)
cest-31	NP_504692.3	COesterase	16..522	CDD:395084	143/573 (25%)