Protein Alignment CG12869 and cest-7

DIOPT Version :9

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_001257187.1
• Gene: cest-7 / 182819
• WormBaseID: WBGene00007693
• Length: 606
• Species: Caenorhabditis elegans
• Alignment Length: 686
• Identity: 153/686 - (22%)
• Similarity: 263/686 - (38%)
• Gaps: 180/686 - (26%)

  Fly    36 GDLIGLKVFPDGTRGAVYAFLGIPYAQAPINELRFAPAKPSSSFNRTLQATTMQPLCPQLANTIY 100
            |.:.|:..|.| .|...|.|.|||:|:.|:..||||..:..:::|..|..:.....|  |:|:
 Worm    45 GKVRGITDFSD-KRNHKYIFKGIPFAKPPLGLLRFALPEEPNTWNGVLDGSKYSAAC--LSNS-- 104

  Fly   101 DESSDGSMPRSVSTDEDCLYLNIWTPESGMRYGKLPIVVIVTGEEFAYD----WPRNRINGLD-L 160
              |...:...::|  |||||:||:|.|..:.: |.|::|...|..|..|    :|...|  |: .
 Worm   105 --SLASAQQENIS--EDCLYINIFTSEYCLAH-KCPVLVYYHGGSFNLDSATMFPDKFI--LERY 162

  Fly   161 AGEGIVVVSVQYRNNIYGWLSLGEQHRNVPGNYGLSDVQMALRWIRRNADAFGGNPDHITLLGHG 225
            ...|||.....||..::|...|||| ..||.|..:.|...:|.::..|..:|||:|:::||:||.
 Worm   163 VDSGIVFAIPAYRLGVFGQFYLGEQ-GIVPANLLIHDCIRSLNFVHDNIASFGGDPNYVTLMGHS 226

  Fly   226 SGGAPLALVATLEDSSQV-------KQLVLMSPGPIMRALGQ-NHQKWIVETGQVLVQKLGCQFE 282
            |||   .||..:..|:|:       :|.:::|      ::|. ..:...:.....:.::..|..|
 Worm   227 SGG---QLVNAMGFSNQIDPEKKLFQQFIVLS------SIGMYGFEDLQIGNSYEIARRHNCTSE 282

  Fly   283 EAQRRQLMGCLRRKSREDLLRA-----------YESVYNHGNGSSQLGVILPEGLPLEQRL---- 332
            .:|  :::.|:|......||:.           ::::           :..|..:.::|:|
 Worm   283 NSQ--EIVDCMRNIDALQLLQTQTVMDDVDLLFFKAI-----------IRAPPLMDVKQKLSEFK 334

  Fly   333 RNKTLPPVLLGITSNE--------GAFLQDYWLDVAREGQVALHKYINHTLLPNVMRALESVGEE 389
            .|.|...:|.|:|.||        |.::...:||           :.|.....||.|
 Worm   335 ENVTARNMLCGVTDNEFTIFKYPDGYYISATFLD-----------FENPVDTVNVYR-------- 380

  Fly   390 SSTQLAAIRWRYFNGKGEGVSHLLAGMQRLLSESLYELPYSRILELLNGTTSYAYVFD------H 448
              .:...|...:.|.....|         .:|.:.|.       |.|.......|:|:      .
 Worm   381 --NKFTNITPTFVNSDSSAV---------FVSAATYS-------EALTNAGGNVYLFESRQKPFS 427

  Fly   449 SHSMDMRGRRNLFGGASHSSDLPLLLGPSLFQQIARRRFSGEEEQLCRKIRGAFANFIKNGNPTP 513
            .|..||:....:....:|::|:.:|  .|.:.::                   ..||.|.|:|:|
 Worm   428 MHVTDMQYFIGIHREKNHTTDMDIL--DSFYSKL-------------------LVNFTKFGSPSP 471

  Fly   514 GRIYDGWLPY--NKENPFVYSLG-EQAKTP--QTGSVDEAEVDKLLRGETGAPGLDRSLSRSNRH 573
                 .|..|  :|.|.....:. ||...|  :.|..:|.....|:    ....:||::.....:
 Worm   472 -----NWEKYDPSKMNFMAMEIDTEQGIEPKMENGFHEELVNFWLI----NMMQIDRNIIEMKLN 527

  Fly   574 DTYRAAPSNSYTASNQLDS---GYSNHLQMVYGFWQVLMPLEREEDLRGGGALGQRVRLLEASAD 635
            ..|     ||:....||.:   |....|.::|.     ..:...|:|.....|.|
 Worm   528 GEY-----NSFDGRAQLTTKHIGVPTSLPIIYA-----PAVSDPENLELISVLNQ---------- 572

  Fly   636 AARYRQGFYAMLGLVCLLLACL---CLCVYLLKRDP 668
                 ..||..:.|:.::::.|   |.....:||.|
 Worm   573 -----WWFYVSILLLFVIVSVLFIVCKKAVNVKRQP 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	128/551 (23%)
cest-7	NP_001257187.1	Abhydrolase	34..510	CDD:304388	130/562 (23%)
		Aes	<135..>236	CDD:223730	37/106 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000