Protein Alignment CG12869 and ace-1

DIOPT Version :10

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_510660.1
• Gene: ace-1 / 181706
• WormBaseID: WBGene00000035
• Length: 620
• Species: Caenorhabditis elegans
• Alignment Length: 550
• Identity: 134/550 - (24%)
• Similarity: 216/550 - (39%)
• Gaps: 98/550 - (17%)

  Fly    31 IKLEQGD-LIGLKVFPDGTRGAVYAFLGIPYAQAPINELRFAPAKPSSSFNRTLQATTMQPLCPQ 94
            |.|..|. |.|.:|... |...:..|.|||:|:.|:..|||...||...:...|.|||....|.|
 Worm    21 IHLHDGSPLFGEEVLSQ-TGKPLTRFQGIPFAEPPVGNLRFKKPKPKQPWRIPLNATTPPNSCIQ 84

  Fly    95 LANTIYDESSDGSM-PRSVSTDEDCLYLNIWTPESGMRYGKLPIVVIVTGEEF--------AYDW 150
            ..:|.:.:....:| ..:....|||||||::.|.......||.::|.|.|..|        .||
 Worm    85 SEDTYFGDFYGSTMWNANTKLSEDCLYLNVYVPGKVDPNKKLAVMVWVYGGGFWSGTATLDVYD- 148

  Fly   151 PRNRINGLDLAGEGIVVVSVQYRNNIYGWLSLGEQHRNVPGNYGLSDVQMALRWIRRNADAFGGN 215
              .||..::   |.:::|::.||.:|:|:|.:...  ..|||.|:.|..:|::|:.:|.|.|||:
 Worm   149 --GRILTVE---ENVILVAMNYRVSIFGFLYMNRP--EAPGNMGMWDQLLAMKWVHKNIDLFGGD 206

  Fly   216 PDHITLLGHGSGGAPLALVATLEDSSQVKQLVLMSP--GPIM-RAL---GQNHQKWIVETGQV-- 272
            ...|||.|..:|.|.::             :.::||  .|.. ||:   |.....|.:|...|
 Worm   207 LSRITLFGESAGAASVS-------------IHMLSPKSAPYFHRAIIQSGSATSPWAIEPRDVAL 258

  Fly   273 -----LVQKLGC---QFEEAQRRQLMGCLRRKSREDLLRAYESVYNHGNGSSQL-----GVILPE 324
                 |...:.|   ........:::.|.:| :..|.||..|.......|....     |..|.|
 Worm   259 ARAVILYNAMKCGNMSLINPDYDRILDCFQR-ADADALRENEWAPVREFGDFPWVPVVDGDFLLE 322

  Fly   325 GLPLEQRLRNKTLPPVLLGITSNEGAFLQDYWL-------------DVAREGQVALHKYINHTLL 376
            ......:..|.....:|.|...:|..:...|.|             |..::.|:.: |.:...|.
 Worm   323 NAQTSLKQGNFKKTQLLAGSNRDESIYFLTYQLPDIFPVADFFTKTDFIKDRQLWI-KGVKDLLP 386

  Fly   377 PNVMR---ALESVGEESSTQLAAIRWRYFNGKGEGVSHLLAGMQRLLSE-----SLYELPYSRIL 433
            ..:::   .|.:|..|...|...:..|.:          :..|.::|.:     |:.|:   .:.
 Worm   387 RQILKCQLTLAAVLHEYEPQDLPVTPRDW----------INAMDKMLGDYHFTCSVNEM---ALA 438

  Fly   434 ELLNGTTSYAYVFDHSHSMDMRGRRNLFGGASHSSDLPLLLGPSLFQQIARRRFSGEEEQLCRKI 498
            ...:|..:|.|.|.|..|......   :.|..|..::..:.|..|.|:  |..::.||.:|..:.
 Worm   439 HTKHGGDTYYYYFTHRASQQTWPE---WMGVLHGYEINFIFGEPLNQK--RFNYTDEERELSNRF 498

  Fly   499 RGAFANFIKNGNPTPGR----IYDGWLPYN 524
            ...:|||.|.|:|....    ..|.|..||
 Worm   499 MRYWANFAKTGDPNKNEDGSFTQDVWPKYN 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	133/549 (24%)
ace-1	NP_510660.1	Esterase_lipase	20..543	CDD:238191	133/549 (24%)