Protein Alignment CG12869 and cest-19

DIOPT Version :9

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_509187.4
• Gene: cest-19 / 180973
• WormBaseID: WBGene00020125
• Length: 607
• Species: Caenorhabditis elegans
• Alignment Length: 550
• Identity: 140/550 - (25%)
• Similarity: 232/550 - (42%)
• Gaps: 124/550 - (22%)

  Fly    19 HLSPYISAQQTHIKLEQGDLIGLKVFPDGTRGAVYAFLGIPYAQAPINELRFAPAKPSSSFNRTL 83
            |:||:      .:::..|.:.|.::..||...:|  |.|||:|..|:..|||...|..:.:...:
 Worm    22 HISPF------ELRVNSGAIRGERLLTDGQDYSV--FKGIPFAMPPVGYLRFQMPKEPAKWRGVM 78

  Fly    84 QATTMQPLCPQLANTIYDESSDGSMPRSVS-TDEDCLYLNIWTPESGMRY--GKLPIVVIVTGEE 145
            .||....:|.|    ..||:..|...|.|: ..|||||||:::| :..:|  ...|::|.:.|..
 Worm    79 NATQYSAMCMQ----NIDENDAGEPERYVAHVSEDCLYLNVFSP-TPYQYTNDTYPVIVFIHGGR 138

  Fly   146 F----AYDWPRNRINGLDLAGEGIVVVSVQYRNNIYGWLSLGEQHRNVPGNYGLSDVQMALRWIR 206
            |    ..|.|:..|.. :.....||.|:..||....|:.|.|:.  .:|||.||.|...||:|::
 Worm   139 FQTGSGSDIPQRAILS-NFVSRKIVFVTFNYRLGPLGFASTGDS--VLPGNIGLWDQIWALKWVK 200

  Fly   207 RNADAFGGNPDHITLLGHGSGGAPLALVATLEDSSQVKQLVLMSPGPIMRALGQNHQKWIVETGQ 271
            .||:.|||:|.:|.|:|||:|.|..:|:|....:..:.|.||:..|..:       |..:|...|
 Worm   201 ANAEVFGGDPSNILLMGHGTGAASASLLALSPRAEGLFQKVLLMSGSAL-------QPGVVRNTQ 258

  Fly   272 V-----LVQKLGCQ-FEEAQRRQLMGCLRRKSREDLLR-------AYESVYNHGNGSSQLGVILP 323
            |     :..:.||: |..:   :|:.|.|::|:|::.:       .||......:|   :|.|||
 Worm   259 VNATWNMNDRFGCRAFNSS---ELLDCARKRSKEEIFQYKRLHFDDYEEFVPIIDG---VGGILP 317

  Fly   324 EGLPLEQRLRNKTLPPVLLGITSNEGA------------FLQDYWLD---VAREGQVALHKYINH 373
            |  |.||...::...|:::|.|.:|.:            |....|.:   :|....:...::.||
 Worm   318 E--PPEQLTLHRRKTPIVIGTTKDESSLRILLLNEKDLNFSSITWENGETLADNLTLGFKQFQNH 380

  Fly   374 TLLPNVMRALESVGEESSTQLAAIRWRYFNGKGEGVSHLLAGMQRLLSESLYELPYSRILE--LL 436
            .|:....:: |.|..:.......             |.|...:.::.|...|:.|.|::..  |.
 Worm   381 RLISQGCKS-EYVWTQVDPSFPE-------------SVLFNSLLKMYSHFWYDAPASQLATYYLK 431

  Fly   437 NGTTSYAYVFDH-----------SHSMDMRGRRNLFGGASHSSDLPLLLGPSLFQQIARRRFSGE 490
            :....|.|.|||           .|.:|   :.::|.                    ...||..:
 Worm   432 HDLPVYLYSFDHISENFYDIDRAFHGVD---KLHIFN--------------------VTPRFLNK 473

  Fly   491 EE----QLCRKIRGAF----ANFIKNGNPT 512
            .:    ||.:::...|    |||...|.||
 Worm   474 RKDMNWQLDQRVVEIFSELVANFALYGTPT 503

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	136/541 (25%)
cest-19	NP_509187.4	Abhydrolase	27..544	CDD:389770	136/538 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D233524at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920