Protein Alignment CG12869 and cest-26

DIOPT Version :10

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_001368609.1
• Gene: cest-26 / 180715
• WormBaseID: WBGene00017478
• Length: 585
• Species: Caenorhabditis elegans
• Alignment Length: 565
• Identity: 145/565 - (25%)
• Similarity: 239/565 - (42%)
• Gaps: 125/565 - (22%)

  Fly    31 IKLEQGDLIGLKVFPDGTRGAVYAFLGIPYAQAPINELRFAPAKPSSSFNRTLQATTMQPLCPQL 95
            ::...|.:.|.::..|..| .|..|||||:|:||:.:|||...:.:..::...:.....|..||
 Worm    44 VRTRNGLVEGFRIKIDDDR-EVDMFLGIPFAKAPVGDLRFKNPEHTEDWDGVKKCVRFGPRAPQ- 106

  Fly    96 ANTIYDESSDGSMPRSVSTDEDCLYLNIWTP---ESGMRYGKLPIVVIVTGEEFAYDWPRNRING 157
            |:..::..:.|     |...|||||||:::|   ...:..|..|::|.|.|..|..|   :.:..
 Worm   107 ADFFWERFTLG-----VGKSEDCLYLNVFSPTWKAEEVSNGLHPVMVYVHGGGFLID---SAVKY 163

  Fly   158 LD------LAGEGIVVVSVQYRNNIYGWLSLGEQHRNVPGNYGLSDVQMALRWIRRNADAFGGNP 216
            .|      |...|:|||::|||..:.|:.|.|:|  ..|||.||.|:.|||:|:|.|..||||:|
 Worm   164 GDEGIAKYLCRHGVVVVTIQYRLGLLGFFSTGDQ--VCPGNLGLWDMTMALQWVRDNVHAFGGDP 226

  Fly   217 DHITLLGHGSGGAPLALVATLEDSSQV-KQLVLMSPGPIMRALGQNHQKWIVETGQVLVQKLGCQ 280
            ..:|:.|..:||..:.|::....|..: .|:|.|:        |....:|.......||.  .|:
 Worm   227 RKVTVFGQSAGGVSVDLLSLSPHSRDLFHQVVPMA--------GNGECEWSTVGKNRLVN--ACR 281

  Fly   281 -------FEEAQRR------QLMGCLR-RKSREDLLRAYES--VYNHGNGSSQLGV--------- 320
                   ::|.|.|      .::..|| ||.||     :|.  :...|...|::|:
 Worm   282 EFAYRKCWDEKQARDENASESMLEFLRTRKERE-----FEKRLLTRKGVDVSKIGLDLAPVIGSK 341

  Fly   321 ---ILPEGLPLEQRLRNKTLPP--VLLGITSNEGAFLQDYWLDVAREGQVALHKYINHTLLPNVM 380
               .||:.:   :.|| |..|.  :::|...:||.....  |..:...:..:.|.:  .||
 Worm   342 PSDFLPKSI---EELR-KEAPKKNIMVGTCEHEGLLFAS--LGPSNFDEKGIDKLL--ALL---- 394

  Fly   381 RALESVGEESSTQLAAIR-------WRYFNGKGEGVSHLLAGMQRLLSESLYELPYSRILELLNG 438
                 :.||:.....|:|       .:..:...:.......|..:|.|:          |.:.||
 Worm   395 -----ITEENHEDFEALREEAKKMYLKKLSDDEDDKEVAARGYIQLYSD----------LFVNNG 444

  Fly   439 TTSYA------------YVFDHSH--SMDMRGRRNLFGGASHSSDLPLLLGPSLFQQIARRRFSG 489
            |.:||            |.||:.:  |..:...|..|..|:|.::|..:.|.|:   :...|::.
 Worm   445 TYNYAEKMTKLGNKVFMYSFDYCNPRSFGILSLRAPFRAATHCTELAYIFGVSI---VFNYRYNE 506

  Fly   490 EEEQLCRKIRGAFANFIKNGNPTPGRIYDG------WLPYNKENP 528
            .:..:...:...:.||.|.|||. |:..|.      |.|.:||.|
 Worm   507 SDRAMLDLMTKMWTNFAKYGNPN-GQYEDSTVFDFKWEPTSKEEP 550

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	145/565 (26%)
cest-26	NP_001368609.1	COesterase	40..575	CDD:395084	145/565 (26%)