Protein Alignment CG12869 and cest-1.1

DIOPT Version :9

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_506506.1
• Gene: cest-1.1 / 179915
• WormBaseID: WBGene00011362
• Length: 673
• Species: Caenorhabditis elegans
• Alignment Length: 610
• Identity: 153/610 - (25%)
• Similarity: 245/610 - (40%)
• Gaps: 117/610 - (19%)

  Fly    10 ILRLLPILIHLSPYISAQQTHIKLE----QGDLIGLKVFPDGTRGAVYAFLGIPYAQAPINELRF 70
            :|:...:|:.:..|:..:   ::|.    :|.::.:...|.|.:.|. .|||||:.:.||.:||:
 Worm     1 MLKPATVLLLIQMYVCKR---VQLSSGTIEGKILNISYSPLGNQSAT-VFLGIPFVEPPIGDLRY 61

  Fly    71 APAKPSSSFNRTLQATTMQPLCPQLANTIYDESSDGSMPRSVSTDEDCLYLNIWTPESGMRYGKL 135
            ...:|..|:...|.....:..|...|...|.....|.:      .|||||||:.|.|..:.....
 Worm    62 RKPRPPKSWEGVLVTNEYKSACMSNATKTYKNKFGGPI------SEDCLYLNVLTNEYCLENKNC 120

  Fly   136 PIVVIVTG-----EEFAYDWPRNRINGLDLAGEGIVVVSVQYRNNIYGWLSLGEQHRNVPG--NY 193
            .:::||.|     |..:...|...||.....|..||||:..||   .|..|.| |.....|  |:
 Worm   121 SVMMIVHGGGYLTESASTFNPEILINNFVGQGRNIVVVTFNYR---LGLFSFG-QFNGDRGDKNF 181

  Fly   194 GLSDVQMALRWIRRNADAFGGNPDHITLLGHGSGGAPL-ALVATLEDSSQVKQLVLMSPGPIMRA 257
            ||.|:..::.|:||..:.||||.:.|||.||.:|.:.: |..::......|.|.::|| .|:...
 Worm   182 GLYDMIESVNWVRREIENFGGNKNRITLAGHSAGASMIVAFTSSPLTKGLVHQQIIMS-APMTNM 245

  Fly   258 LGQNHQKWIVETGQVLVQKLGC--------QFEEAQRRQLMGCLRRKSREDLLRAYESVYNHGNG 314
            ..:::.|.:.    |:.|.:||        :..|.|......|||:||.:.:|.|  .::...|.
 Worm   246 SKKSNFKGMT----VMAQMVGCLSEEIGFNKLSEEQVENTYSCLRKKSAQQILDA--QLWLLQNS 304

  Fly   315 SSQLG---------VILPEGLPLEQRLRNKTLPPV--LLGITS---NEGAFLQD-YWLDVAREGQ 364
            :..||         ...||.|     ..:|::.|:  |:|.|:   .|.:::.| .:.|...|..
 Worm   305 TYFLGAPPIDEHFLTDYPENL-----YASKSIYPINTLIGTTTLEVEESSYIIDPAFADKKVELL 364

  Fly   365 VALHKYINHTLLPNVMRALESVGEESSTQLAAIRWRYFNGKGEGVSHLLAGMQRLLSESLYELPY 429
            ..|..:|.:.|.           ||..|.....:.:|.||...         ..|.:|..:   |
 Worm   365 ENLCDHIGYVLY-----------EEPETFSKKCQKQYMNGNSS---------MNLSNEMEF---Y 406

  Fly   430 SRILELLNGTTS-----YAYVFDHSHSMDMRGRRNLFGGASHSSDLPLLLGPSLFQQIARRRFSG 489
            :..::..:..||     :.|.:|:..:.....|........||.||..:.|       ..|....
 Worm   407 TPAIDFADSHTSGNTKVFLYSYDYRGAGPAYDRYLEVRSPHHSEDLIYVFG-------THRGIFA 464

  Fly   490 EEEQLCRKI-RGAFANFIKNGNPTPGRIYDG---WLPYNKEN--PFVYSLGEQAKTPQTGSVDE- 547
            .::.:..|| .|.||:|:...||.|    .|   |..|.|||  .|:.:..:...||  |..|.
 Worm   465 PKDYIIEKIYSGMFADFVNFENPLP----SGDQKWNQYTKENREHFLINFDKNFITP--GMRDNY 523

  Fly   548 --------AEVDKLLRGETGAPGLD 564
                    :.|.|....|..:|.||
 Worm   524 YTEAYEFWSTVGKKSFKEEWSPSLD 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	141/559 (25%)
cest-1.1	NP_506506.1	COesterase	19..531	CDD:278561	144/570 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910