Protein Alignment CG12869 and cest-34

DIOPT Version :9

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_001360105.1
• Gene: cest-34 / 179057
• WormBaseID: WBGene00019652
• Length: 550
• Species: Caenorhabditis elegans
• Alignment Length: 564
• Identity: 130/564 - (23%)
• Similarity: 222/564 - (39%)
• Gaps: 115/564 - (20%)

  Fly    36 GDLIGLKVFPDGTRGAVYAFLGIPYAQAPINELRFAPAKPSSSFNRTLQATTMQPLCPQLANTIY 100
            |.::| .::..|.: .|:.:||:|||:.|..|:|||...|:..:..|...|...|.||.....:
 Worm    22 GPVLG-NLYRHGDK-EVHGYLGMPYAKPPTGEMRFAKPVPADDWTETRDCTKYGPRCPPSGQGL- 83

  Fly   101 DESSDGSMPRSVSTDE-DCLYLNIWTP--ESGMRYGKLPIVVIVTGEEFAYDWPRNRIN---GLD 159
               ..|........|| :.|.:|::.|  ||.......|::|.|.|..|.....|...:   ...
 Worm    84 ---EKGMFVNPDEPDEANGLSVNVFVPGWESSEYKNARPVMVYVHGGGFEISSSREFCDYSISST 145

  Fly   160 LAGEGIVVVSVQYRNNIYGWLSLGEQHRNVPGNYGLSDVQMALRWIRRNADAFGGNPDHITLLGH 224
            |..:.:::|::.||..|.|:.:.|::  ..|||:||.|..:||:|::::..:|||:|:::||.|.
 Worm   146 LPMKDVILVTMNYRLGILGFFTTGDE--VCPGNFGLWDQTLALQWVQKHIASFGGDPNNVTLFGQ 208

  Fly   225 GSGGAPLALVATLEDSSQVKQLVLMSPGPIMRALGQNHQKWIVETGQVLVQKLGCQFEEAQRRQL 289
            .:|||.:.|:.....|..:.|.|:...|..|........:........::.:||  |..:..::.
 Worm   209 SAGGACVDLLTLSPHSRDLFQKVVPMSGSAMCEFAMRTAENEAHVFDDILARLG--FTGSGSKER 271

  Fly   290 MGCLRRKSREDLLRAYESVYNHGNGSSQL-----GVILPEGLPLEQRLRNKTLPPVLLGITSNEG 349
            :..:|....:.:.......|.. :|...|     |...|:  ||::..::.:...::.||..|||
 Worm   272 LEFMRSLPCDKITGKTGYTYKQ-SGFMSLCPNYDGDFFPK--PLDELRKDASKRILMTGIVGNEG 333

  Fly   350 AFL--------------------QDYWLDVAREGQVALHKYINHTLLPNVMRALESVGEESSTQL 394
            ...                    :||..||..:.: .:.|.|......|:     |.|:|.:...
 Worm   334 LLFAFDRNTPYKDYTDLLRLKIEEDYKEDVVDDVE-GIRKEIFEYYTKNI-----SEGDEEAIMR 392

  Fly   395 AAIRWRYFNGKGEGVSHLLAGMQRLLSESLYELPYSRILELLNGTTSYAYVFDHSHSMDMRGRRN 459
            .|..:     .|:.:.|  .|: |..:::..|          :|...:.|.||:.:.   .|...
 Worm   393 KAAEF-----VGDSIFH--TGV-RATAQNAAE----------HGDEVWLYNFDYCNP---DGFAP 436

  Fly   460 LFG-----GASHSSDLPLLLGPSLFQQIARRRFSGEEEQL--CRKIRGAFANFIKNGNPT----- 512
            |.|     ..:|..:|..|.|..:..     :|...||:|  ..|....||||.|.|||.
 Worm   437 LKGYLPYIEPTHGMELRYLFGDGIIS-----KFEPTEEELKMLDKFTTMFANFAKYGNPNETGSS 496

  Fly   513 ---------PGRIYDGWLPYNKENPFVYSLGEQAKTPQTGSVDE 547
                     |||.|                  :...|.:|..||
 Worm   497 AWEKFDPARPGRHY------------------RISYPNSGMEDE 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	126/556 (23%)
cest-34	NP_001360105.1	COesterase	15..530	CDD:365897	130/564 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D233524at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910