Protein Alignment CG12869 and cest-24

DIOPT Version :9

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_504613.1
• Gene: cest-24 / 179017
• WormBaseID: WBGene00020891
• Length: 658
• Species: Caenorhabditis elegans
• Alignment Length: 564
• Identity: 142/564 - (25%)
• Similarity: 224/564 - (39%)
• Gaps: 169/564 - (29%)

  Fly    31 IKLEQGDLIGLKVFPDGTRGAVY-AFLGIPYAQAPINELRFAPAKPSSSFNRTLQATTMQPLCPQ 94
            ::::||.|.|.:|  ...:|.:. .|.|||||:.|:.||||...:|..::....:       |.:
 Worm    98 VRVQQGLLEGFRV--KTAKGDLCDVFHGIPYAEPPVGELRFQKPQPPKAWEGIRK-------CNK 153

  Fly    95 LAN-TIYDESS-DGSMPRSVSTDEDCLYLNIWTPESGMRYG-KLPIVVIVTGEEFAYD----WPR 152
            ..| :|:.|.. |.::| |.:..|||||||::.|:  :|.. |.|::..:.|..:..|    :..
 Worm   154 YPNRSIHKEMPWDKALP-SANQSEDCLYLNVFAPK--IREDKKYPVLFYIHGGGYVMDSAERYTA 215

  Fly   153 NRINGLDLAGEGIVVVSVQYRNNIYGWLSLGEQHRNVPGNYGLSDVQMALRWIRRNADAFGGNPD 217
            ..|..| |....|:||:..||....|:||.|:.  ..||||||.|:..|:||:..|..:|||:|:
 Worm   216 KNICKL-LVSREIIVVTFHYRLGFLGFLSTGDD--VCPGNYGLFDMLEAMRWVHANISSFGGDPE 277

  Fly   218 HITLLGHGSGGAPLALV--ATLEDSSQVKQLVLMSPGPIMRALGQNH------QKWIVETGQVLV 274
            :|||.|..:|.|...|:  :.|......:::|:........|...||      :||        .
 Worm   278 NITLSGQSAGAAAADLLSFSPLTKGLFKRKIVMGGNSYCHWATTSNHDIREYCKKW--------A 334

  Fly   275 QKLGC--QFEEAQRRQLMGCLRRKSREDLLRAYESV--YNHGNGSSQLGVILPEGLPLEQRLRNK 335
            ::||.  |...|.:|:                 |||  :|..||
 Worm   335 KRLGWKPQLNYANKRE-----------------ESVDIFNFFNG--------------------- 361

  Fly   336 TLPPVLLGIT---SNEGAFLQDYWLDVAREGQVALHKYINHTLLPNVMRALESV----------G 387
             ||...||:|   ||          .:.:|.|:.|...|:..:||:.::.|...          |
 Worm   362 -LPTSKLGMTMFFSN----------TIFKECQLPLAPVIDGEILPHDLKVLRETQEHVPSLVGGG 415

  Fly   388 EESSTQLAAIRWRYFNGKGEGVS---HLLAGMQRL-------LSESLY-ELPYSR---------I 432
            |..:....||  ....|..:.::   .:|:...||       ::|.:| :.|..|         .
 Worm   416 EYEALLFCAI--GLLRGTEKEINSAIDVLSRKNRLSRSKIEAMTEKVYGDSPALRADSKARKMFF 478

  Fly   433 LELLN------------------GTTSYAYVFDHSHSMDMRGRRN---LFGGASHSSDLPLL--- 473
            ::|::                  |...|.|.||| .|..|.|...   .|.|.:|:|:|..|
 Worm   479 VQLISDIFANYGNYRFMRDCQQRGVECYGYSFDH-QSKQMWGWLQHVVPFTGGTHTSELSYLFDC 542

  Fly   474 ------LGPSLFQQIARRRFSGEEEQLCRKIRGAFANFIKNGNP 511
                  ||.:...::.    ||.....       |.||:|.|.|
 Worm   543 NYMSAPLGMNKTDKVV----SGMTADY-------FTNFVKFGTP 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	142/564 (25%)
cest-24	NP_504613.1	COesterase	97..608	CDD:278561	142/564 (25%)
		Aes	<183..>285	CDD:223730	37/106 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11559
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.100