Protein Alignment CG12869 and cest-35.1

DIOPT Version :9

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_504400.1
• Gene: cest-35.1 / 178912
• WormBaseID: WBGene00015067
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 567
• Identity: 128/567 - (22%)
• Similarity: 226/567 - (39%)
• Gaps: 132/567 - (23%)

  Fly    29 THIKLEQG-DLIGLKVFPDGTRGAVY--------AFLGIPYAQAPINELRFAPAKPSSSFNRTLQ 84
            :|:|.|.. :::.....|  .||.:|        .:||||:|:|||.||||..:..:..:...|.
 Worm     6 SHLKPEHNTEVLNASCGP--IRGNIYEHDDKIVDGYLGIPFAKAPIGELRFKKSVEAEKWTEPLD 68

  Fly    85 ATTMQPLCPQLANTIYDESSDGSM--PRSVS----TDEDCLYLNIWTP--ESGMRYGKLPIVVIV 141
            .....|.|||       ..:.|:|  |::.:    .:::||.||::.|  :|......||::|..
 Worm    69 CYKYGPGCPQ-------SGALGAMIVPQASAIREFAEDNCLTLNVFAPKWKSAEFPNGLPVIVYF 126

  Fly   142 TGEEFAYDWPRNRINGLDLAG----EGIVVVSVQYRNNIYGWLSLGEQHRNVPGNYGLSDVQMAL 202
            .|..|...: .:..:...|.|    :.:::|:..||....|:.:.|:....  ||:||.|..:||
 Worm   127 YGGGFEVGF-SSMFDDYSLTGTLPLKDVILVTPNYRIGPLGFFATGDDVSR--GNWGLWDQALAL 188

  Fly   203 RWIRRNADAFGGNPDHITLLGHGSGGAPLALVATLEDSSQVKQLVLMSPGPIMRALGQNHQKWIV 267
            :|::::..:|||:|.::|:.|..:|||.:..::             :||     ...:...|:|.
 Worm   189 QWVQKHIKSFGGDPSNVTISGTSAGGASVDFLS-------------LSP-----HANKYFHKFIP 235

  Fly   268 ETGQVLVQKLGCQFEEAQRRQLMGCLRRK----------SREDLLRAYES----VYNHGNG---- 314
            .:|...     |.| ..:.:.:.|.:.|:          ..|.||..|:|    ::....|
 Worm   236 MSGAAT-----CPF-GIRSKDVEGLIFREFAKHHGYAGNDSESLLHWYQSQDAEIFLKAEGFKYP 294

  Fly   315 SSQLGVILP--EG----LPLEQRLRNKTLPPVLLGITSNEGAFLQDYWLDVAREGQVALHKYINH 373
            :|.:...:|  :|    .|.::..:.......::.:...||...::::     .||.:..:.:..
 Worm   295 ASGMFSFVPNYDGDFFPKPFDELRKEAPKLDAIVSVAEYEGLGFEEFY-----PGQKSPQEVLTA 354

  Fly   374 TLLPNVMRALESV----------------GEESSTQLAAIRWRYFNGKG--EGVSHLLA-GMQRL 419
            .|.|.|:|..|.|                ||:...:|..|...|:...|  :.|..|.. |....
 Worm   355 ALGPEVVRNREEVVKKAVEAYLENIEDKSGEKIGKKLVEIFGDYYFSVGVFDTVRSLAKYGNNVY 419

  Fly   420 LSESLYELPYSRILELLNGTTSYAYVFDHSHSMDMRGRRNLFGGASHSSDLPLLLGPSLFQQIAR 484
            ||...|..|.:.|                     |.|....|..|||..|:..:||..:.:
 Worm   420 LSSFNYFNPETPI---------------------MFGENRPFNAASHGCDIRYILGDGIGE---- 459

  Fly   485 RRFSGEEEQLCRKIRGAFANFIKNGNPTPGRIYDGWLPYNKENPFVY 531
              ||.|:.::...:.....||.|.|||....:...|..|:.:||..|
 Worm   460 --FSKEDRKVMDMMGTYLTNFAKYGNPNGKGVSIPWEKYSLDNPGRY 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	128/567 (23%)
cest-35.1	NP_504400.1	COesterase	14..516	CDD:278561	125/559 (22%)
		Aes	<106..>214	CDD:223730	28/110 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900