Protein Alignment CG12869 and cest-32

DIOPT Version :10

• Sequence 1: NP_001369085.1
• Gene: CG12869 / 36616
• FlyBaseID: FBgn0033943
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_504397.1
• Gene: cest-32 / 178909
• WormBaseID: WBGene00016862
• Length: 545
• Species: Caenorhabditis elegans
• Alignment Length: 571
• Identity: 135/571 - (23%)
• Similarity: 225/571 - (39%)
• Gaps: 127/571 - (22%)

  Fly    17 LIHLSPYISAQQTHIKLEQGDLIGLKVFPDGTRGAVYAFLGIPYAQAPINELRFAPAKPSSSFNR 81
            |.||.|..|.:.  :....|.:|| .::....: .|..:||||:|:|||.||||.....:..:.:
 Worm     5 LSHLKPEASLEV--LNASCGPVIG-NIYRHDDK-IVNGYLGIPFAKAPICELRFKKPVEAEKWTK 65

  Fly    82 TLQATTMQPLCPQLANTI-------YDESSDGSMPRSVSTDEDCLYLNIWTP--ESGMRYGKLPI 137
            .|......|.|||..:.|       |.|.:          :::||.|||:.|  :|......|||
 Worm    66 PLNCHKYGPGCPQSGHMISNLLPPGYREFA----------EDNCLNLNIFAPSWKSEEFPNGLPI 120

  Fly   138 VVIVTGEEFAYDWPRNRINGLDLAG----EGIVVVSVQYRNNIYGWLSLGEQHRNVPGNYGLSDV 198
            :|...|..|...: .:..:...|:|    :.::||:..||....|:::.|::...  |||||.|.
 Worm   121 MVYFHGGGFEIGF-SSMFDDYSLSGTLPLKDVIVVTANYRVGPLGFMTTGDEVSR--GNYGLWDQ 182

  Fly   199 QMALRWIRRNADAFGGNPDHITLLGHGSGGAPLALVATLEDSSQVKQLVLMSPGPIMRALGQNHQ 263
            .:||:|::.:..:|||||:.:|:.|..:||....|:|....|:::                  ..
 Worm   183 TLALKWVQEHIKSFGGNPNIVTVCGTSAGGVSAGLLALSPHSNKL------------------FH 229

  Fly   264 KWIVETGQVLVQKLGCQFEEAQRRQLMGCLRR---------KSREDLLRAY---------ESVYN 310
            :::..:|...     |:|....:.|.....|.         :..|.||..|         |:...
 Worm   230 RFMAMSGSAF-----CEFSIRTKEQEAEIFRNFAKHHGYEGEDSESLLEWYKSQPLSKFQETATF 289

  Fly   311 HGNGSSQL-------GVILPEGLPLEQRLRNKTLPPVLLGITSNEG-AFLQDYW-----LDVAR- 361
            ....|..|       |...|:  |.::..|.......:..:...|| .||..:.     :|:.:
 Worm   290 EKKASGFLTFIPNFDGDFFPK--PFDELSREAPKLDAMATVDEYEGLGFLTMFQSRRNDMDIIKS 352

  Fly   362 -------EGQVALHKYINHTLLPNVMRALESVGEESSTQLAAIRWRYFNGKGEGVSHLLAGMQRL 419
                   |..|.:.|.|....:.|:.:..:...|:...||.:..|  ||         :..::.:
 Worm   353 SFGSDVVENAVDVQKRIMEFYMKNIDKNDDKAVEKRLIQLISDSW--FN---------IGALETV 406

  Fly   420 LSESLYELPYSRILELLNGTTSYAYVFDHSH--SMDMRGRRNLFGGASHSSDLPLLLGPSLFQQI 482
            .:.:.|            |:.:|...||:.:  |.|.......|..|:|.|:|..:||..:
 Worm   407 KTSTKY------------GSNAYLGSFDYYNMGSNDPYATWFPFKAANHGSELKYMLGEGM---- 455

  Fly   483 ARRRFSG-EEEQLCRKIRGAF-ANFIKNGNPTPGRIYDGWLPYNKENPFVY 531
              .:||. |||.....:.|.. |||:|.|||......:.|..|..|.|:.|
 Worm   456 --GKFSPIEEEFKVIDMMGTLTANFVKYGNPNGINGPELWKKYTPEKPYSY 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12869	NP_001369085.1	COesterase	27..541	CDD:395084	130/561 (23%)
cest-32	NP_504397.1	COesterase	16..519	CDD:395084	130/560 (23%)